Search Results - "James, Johanna D."
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The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
Published in Genes & development (15-12-2011)“…Recent molecular classification of glioblastoma (GBM) has shown that patients with a mesenchymal (MES) gene expression signature exhibit poor overall survival…”
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Combination of Small Extracellular Vesicle-Derived Annexin A2 Protein and mRNA as a Potential Predictive Biomarker for Chemotherapy Responsiveness in Aggressive Triple-Negative Breast Cancer
Published in Cancers (29-12-2022)“…Small extracellular vesicles (sEVs), mainly exosomes, are nanovesicles that shed from the membrane as intraluminal vesicles of the multivesicular bodies, serve…”
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Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
Published in Cancer cell (09-09-2013)“…Despite extensive study, few therapeutic targets have been identified for glioblastoma (GBM). Here we show that patient-derived glioma sphere cultures (GSCs)…”
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