Search Results - "James, D. J."

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program by Ren, Decheng, Tu, Ho-Chou, Kim, Hyungjin, Wang, Gary X, Bean, Gregory R, Takeuchi, Osamu, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D, Cheng, Emily H.-Y

“…Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated remains unsettled. We provide in…”
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Constraints on Dark Matter Properties from Observations of Milky Way Satellite Galaxies by Nadler, E O, Drlica-Wagner, A, Bechtol, K, Mau, S, Wechsler, R H, Gluscevic, V, Boddy, K, Pace, A B, Li, T S, McNanna, M, Riley, A H, García-Bellido, J, Mao, Y-Y, Green, G, Burke, D L, Peter, A, Jain, B, Abbott, T M C, Aguena, M, Allam, S, Annis, J, Avila, S, Brooks, D, Carrasco Kind, M, Carretero, J, Costanzi, M, da Costa, L N, De Vicente, J, Desai, S, Diehl, H T, Doel, P, Everett, S, Evrard, A E, Flaugher, B, Frieman, J, Gerdes, D W, Gruen, D, Gruendl, R A, Gschwend, J, Gutierrez, G, Hinton, S R, Honscheid, K, Huterer, D, James, D J, Krause, E, Kuehn, K, Kuropatkin, N, Lahav, O, Maia, M A G, Marshall, J L, Menanteau, F, Miquel, R, Palmese, A, Paz-Chinchón, F, Plazas, A A, Romer, A K, Sanchez, E, Scarpine, V, Serrano, S, Sevilla-Noarbe, I, Smith, M, Soares-Santos, M, Suchyta, E, Swanson, M E C, Tarle, G, Tucker, D L, Walker, A R, Wester, W

“…We perform a comprehensive study of Milky Way (MW) satellite galaxies to constrain the fundamental properties of dark matter (DM). This analysis fully…”
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Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis by Kim, Hyungjin, Tu, Ho-Chou, Ren, Decheng, Takeuchi, Osamu, Jeffers, John R., Zambetti, Gerard P., Hsieh, James J.-D., Cheng, Emily H.-Y.

“…While activation of BAX/BAK by BH3-only molecules (BH3s) is essential for mitochondrial apoptosis, the underlying mechanisms remain unsettled. Here we…”
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Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies by Cheng, Emily H.-Y, Kim, Hyungjin, Rafiuddin-Shah, Mubina, Tu, Ho-Chou, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D

“…Although the BCL-2 family constitutes a crucial checkpoint in apoptosis, the intricate interplay between these family members remains elusive. Here, we…”
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The evolution of parental care in insects: A test of current hypotheses by Gilbert, James D. J., Manica, Andrea

“…Which sex should care for offspring is a fundamental question in evolution. Invertebrates, and insects in particular, show some of the most diverse kinds of…”
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Parental Care Trade‐Offs and Life‐History Relationships in Insects by Gilbert, James D. J., Manica, Andrea

“…Insect parental care is extensive and varied, but its life‐history implications have never been comparatively tested. Using original and literature data, we…”
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Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint by Hsieh, James J.-D, Liu, Han, Takeda, Shugaku, Kumar, Rakesh, Westergard, Todd D, Brown, Eric J, Pandita, Tej K, Cheng, Emily H.-Y

“…Cell cycle checkpoints are implemented to safeguard the genome, avoiding the accumulation of genetic errors. Checkpoint loss results in genomic instability and…”
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Homoclinic dynamics in a spatial restricted four-body problem: blue skies into Smale horseshoes for vertical Lyapunov families by Murray, Maxime, Mireles James, J. D.

“…The set of transverse homoclinic intersections for a saddle-focus equilibrium in the planar equilateral restricted four-body problem admits certain simple…”
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A multicomponent matched filter cluster confirmation tool for eROSITA: initial application to the RASS and DES-SV data sets by Klein, M, Mohr, J J, Desai, S, Israel, H, Allam, S, Benoit-Lévy, A, Brooks, D, Buckley-Geer, E, Carnero Rosell, A, Carrasco Kind, M, Cunha, C E, da Costa, L N, Dietrich, J P, Eifler, T F, Evrard, A E, Frieman, J, Gruen, D, Gruendl, R A, Gutierrez, G, Honscheid, K, James, D J, Kuehn, K, Lima, M, Maia, M A G, March, M, Melchior, P, Menanteau, F, Miquel, R, Plazas, A A, Reil, K, Romer, A K, Sanchez, E, Santiago, B, Scarpine, V, Schubnell, M, Sevilla-Noarbe, I, Smith, M, Soares-Santos, M, Sobreira, F, Suchyta, E, Swanson, M E C, Tarle, G, Collaboration, the DES

“…Abstract We describe a multicomponent matched filter (MCMF) cluster confirmation tool designed for the study of large X-ray source catalogues produced by the…”
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Homoclinic dynamics in a restricted four-body problem: transverse connections for the saddle-focus equilibrium solution set by Kepley, Shane, Mireles James, J. D.

“…We describe a method for computing an atlas for the stable or unstable manifold attached to an equilibrium point and implement the method for the saddle-focus…”
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PUMA and BIM are required for oncogene inactivation-induced apoptosis by Bean, Gregory R, Ganesan, Yogesh Tengarai, Dong, Yiyu, Takeda, Shugaku, Liu, Han, Chan, Po M, Huang, Yafen, Chodosh, Lewis A, Zambetti, Gerard P, Hsieh, James J-D, Cheng, Emily H-Y

“…The clinical efficacy of tyrosine kinase inhibitors supports the dependence of distinct subsets of cancers on specific driver mutations for survival, a…”
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Rigorous numerics for analytic solutions of differential equations: the radii polynomial approach by Hungria, Allan, Lessard, Jean-Philippe, James, J. D. Mireles

“…Judicious use of interval arithmetic, combined with careful pen and paper estimates, leads to effective strategies for computer assisted analysis of nonlinear…”
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p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage by Tu, Ho-Chou, Ren, Decheng, Wang, Gary X, Chen, David Y, Westergard, Todd D, Kim, Hyungjin, Sasagawa, Satoru, Hsieh, James J.-D, Cheng, Emily H.-Y

“…Three forms of cell death have been described: apoptosis, autophagic cell death, and necrosis. Although genetic and biochemical studies have formulated a…”
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Reading between the (Spectral) Lines: Magellan/IMACS Spectroscopy of the Ultrafaint Dwarf Galaxies Eridanus IV and Centaurus I by Heiger, M. E., Li, T. S., Pace, A. B., Simon, J. D., Ji, A. P., Chiti, A., Bom, C. R., Carballo-Bello, J. A., Carlin, J. L., Cerny, W., Choi, Y., Drlica-Wagner, A., James, D. J., Martínez-Vázquez, C. E., Medina, G. E., Mutlu-Pakdil, B., Navabi, M., Noël, N. E. D., Sakowska, J. D., Stringfellow, G. S.

“…Abstract We present a spectroscopic analysis of Eridanus IV (Eri IV) and Centaurus I (Cen I), two ultrafaint dwarf galaxies of the Milky Way. Using…”
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DELVE 6: An Ancient, Ultra-faint Star Cluster on the Outskirts of the Magellanic Clouds by Cerny, W., Drlica-Wagner, A., Li, T. S., Pace, A. B., Olsen, K. A. G., Noël, N. E. D., van der Marel, R. P., Carlin, J. L., Choi, Y., Erkal, D., Geha, M., James, D. J., Martínez-Vázquez, C. E., Massana, P., Medina, G. E., Miller, A. E., Mutlu-Pakdil, B., Nidever, D. L., Sakowska, J. D., Stringfellow, G. S., Carballo-Bello, J. A., Ferguson, P. S., Kuropatkin, N., Mau, S., Tollerud, E. J., Vivas, A. K.

“…Abstract We present the discovery of DELVE 6, an ultra-faint stellar system identified in the second data release of the DECam Local Volume Exploration (DELVE)…”
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The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations by Huang, Gang, Zhao, Xinghui, Wang, Lan, Elf, Shannon, Xu, Hao, Zhao, Xinyang, Sashida, Goro, Zhang, Yue, Liu, Yan, Lee, Jennifer, Menendez, Silvia, Yang, Youyang, Yan, Xiaomei, Zhang, Pu, Tenen, Daniel G., Osato, Motomi, Hsieh, James J.-D., Nimer, Stephen D.

“…The mixed-lineage leukemia (MLL) H3K4 methyltransferase protein, and the heterodimeric RUNX1/CBFβ transcription factor complex, are critical for definitive and…”
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Macroecology of parental care in arthropods: higher mortality risk leads to higher benefits of offspring protection in tropical climates by Santos, Eduardo S. A., Bueno, Pedro P., Gilbert, James D. J., Machado, Glauco

“…ABSTRACT The intensity of biotic interactions varies around the world, in such a way that mortality risk imposed by natural enemies is usually higher in the…”
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A non-invasive stress assay based upon measurement of free cortisol released into the water by rainbow trout by Ellis, T., James, J. D., Stewart, C., Scott, A. P.

“…A procedure previously used for sex steroids was adapted to extract free cortisol and cortisone from water samples taken from rainbow trout Oncorhynchus mykiss…”
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Sex-biased parental care and sexual size dimorphism in a provisioning arthropod by Field, Jeremy, Shreeves, Gavin, Kennedy, Martyn, Brace, Selina, Gilbert, James D. J

“…The diverse selection pressures driving the evolution of sexual size dimorphism (SSD) have long been debated. Whilst the balance between fecundity selection…”
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Computer assisted error bounds for linear approximation of (un)stable manifolds and rigorous validation of higher dimensional transverse connecting orbits by Mireles James, J.D.

“…•We study error bounds for linear approximations of stable/unstable manifolds.•Maps and Flows are treated by computer assisted arguments.•Bounds on derivatives…”
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