Search Results - "Jallal, B"

A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth by Streicher, K L, Zhu, W, Lehmann, K P, Georgantas, R W, Morehouse, C A, Brohawn, P, Carrasco, R A, Xiao, Z, Tice, D A, Higgs, B W, Richman, L, Jallal, B, Ranade, K, Yao, Y

“…Malignant melanoma is the most aggressive form of skin cancer and its incidence has doubled in the last two decades. It represents only 4% of skin cancer cases…”
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Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway by Higgs, Brandon W, Liu, Zheng, White, Barbara, Zhu, Wei, White, Wendy I, Morehouse, Chris, Brohawn, Philip, Kiener, Peter A, Richman, Laura, Fiorentino, David, Greenberg, Steven A, Jallal, Bahija, Yao, Yihong

“…To characterise activation of the type I interferon (IFN) pathway in patients with systemic lupus erythematosus (SLE), dermatomyositis (DM), polymyositis (PM),…”
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Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis by Greenberg, S A, Higgs, B W, Morehouse, C, Walsh, R J, Won Kong, S, Brohawn, P, Zhu, W, Amato, A, Salajegheh, M, White, B, Kiener, P A, Jallal, B, Yao, Y

“…The objective of this study was to evaluate the relationship between blood mRNA, disease activity and treatment effects in a longitudinal study of patients…”
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Pharmacogenomics and Translational Simulations to Bridge Indications for an Anti-Interferon-α Receptor Antibody by Wang, B, Higgs, B W, Chang, L, Vainshtein, I, Liu, Z, Streicher, K, Liang, M, White, W I, Yoo, S, Richman, L, Jallal, B, Roskos, L, Yao, Y

“…A type I interferon (IFN) gene signature shared by systemic lupus erythematous (SLE) and systemic sclerosis (SSc) was used to evaluate an anti‐type I IFN‐α…”
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Heregulin‐dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3 by Wallasch, C., Weiss, F. U., Niederfellner, G., Jallal, B., Issing, W., Ullrich, A.

“…Amplification and/or overexpression of HER2/neu and HER3 genes have been implicated in the development of cancer in humans. The fact that these receptor…”
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Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression by Hobert, Oliver, Jallal, Bahija, Ullrich, Axel

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The secreted tumor-associated antigen 90K is a potent immune stimulator by ULLRICH, A, SURES, I, SHAWVER, L. K, SCHLESSINGER, J, IACOBELLI, S, D'EGIDIO, M, JALLAL, B, POWELL, T. J, HERBST, R, DREPS, A, MOHAMMAD AZAM, RUBINSTEIN, M, NATOLI, C

“…Immunization of mice with conditioned media from human breast cancer cells yielded the monoclonal antibody SP-2, which recognized an antigen of approximately…”
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Cloning and sequencing of porcine LH-hCG receptor cDNA: variants lacking transmembrane domain by Loosfelt, H. (Institut National de la Sante et de la Recherche Medicale Unite, Kremlin Bicetre, France), Misrahi, M, Atger, M, Salesse, R, Vu Hai-Luv Thi, M, Jolivet, A, Guiochon-Mantel, A, Sar, S, Jallal, B, Garnier, J

“…Complementary DNA clones, encoding the LH-hCG (luteinizing hormone-human choriogonadotropic hormone) receptor were isolated by screening a lambda gt11 library…”
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100 Inhibition of PDGFRalpha in tumor stroma with MEDI-575 enhances activity of carboplatin/paclitaxel and delays tumor regrowth in a NSCLC xenograft model by Steiner, P, Wetzel, L, Schifferli, K, Camara, M, Baffa, R, LaVallee, T, Jallal, B, Coats, S, Trail, P, Chang, Y

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57 Glioblastoma multiforme is characterized by high incidence of PDGFRalpha expression and susceptibility to the PDGFRalphaspecific antibody MEDI-575 in mouse tumor models by Steiner, P, Wetzel, L, Camara, M, Schifferli, K, Baffa, R, LaVallee, T, Coats, S, Jallal, B, Trail, P, Chang, Y

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Tyrosine phosphatase inhibition permits analysis of signal transduction complexes in p185HER2/neu-overexpressing human tumor cells by JALLAL, B, SCHLESSINGER, J, ULLRICH, A

“…The HER2/neu gene encodes a receptor tyrosine kinase that is highly homologous to the epidermal growth factor receptor. Overexpression of the receptor in…”
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Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus by Yao, Yihong, Higgs, Brandon W, Richman, Laura, White, Barbara, Jallal, Bahija

“…Type I interferons are implicated in the pathogenesis of systemic lupus erythematosus (SLE). Type I interferon-inducible mRNAs are widely and concordantly…”
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Novel signaling pathway suggested by SH3 domain-mediated p95vav/heterogeneous ribonucleoprotein K interaction by HOBERT, O, BAHIJA JALLAL, SCHLESSINGER, J, ULLRICH, A

“…The role of the protooncogene product p95vav in signal transduction was investigated by characterizing its interactions with proteins that may represent…”
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PAK4 mediates morphological changes through the regulation of GEF-H1 by Callow, Marinella G, Zozulya, Sergey, Gishizky, Mikhail L, Jallal, Bahija, Smeal, Tod

“…Precise spatial and temporal regulation of Rho GTPases is required in controlling F-actin-based changes in cell morphology. The molecular mechanisms through…”
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Monoclonal antibodies against luteinizing hormone receptor. Immunochemical characterization of the receptor by Vuhai-Luuthi, M T, Jolivet, A, Jallal, B, Salesse, R, Bidart, J M, Houllier, A, Guiochon-Mantel, A, Garnier, J, Milgrom, E

“…Human CG (hCG)-receptor complexes were solubilized from porcine testicular membranes. They were chromatographed on an immunomatrix of Affi-Gel 10-D1E8 anti…”
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Requirement for PAK4 in the Anchorage-independent Growth of Human Cancer Cell Lines by Callow, Marinella G., Clairvoyant, Felix, Zhu, Shirley, Schryver, Brian, Whyte, David B., Bischoff, James R., Jallal, Bahija, Smeal, Tod

“…p21-activated protein kinase (PAK) serine/threonine kinases are important effectors of Rho family GTPases and have been implicated in the regulation of cell…”
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891 Population Pharmacokinetics Analysis of Motavizumab in Children at Risk for Respiratory Syncytial Virus Infection by Zhao, L, Roskos, L, Griffin, P, Losonsky, G A, Groothuis, J R, Jallal, B, Robbie, G

“…Aims: To develop a population pharmacokinetics (PK) model and evaluate the impact of demographic covariates on PK of motavizumab in young children. Methods:…”
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The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn) by Holsinger, Leslie J, Ward, Kevin, Duffield, Bill, Zachwieja, Joseph, Jallal, Bahija

“…The receptor-like protein tyrosine phosphatase DEP1, also known as CD148, is expressed predominantly in epithelial cells, in a variety of tumor cell lines, and…”
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The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis by Yin, Min-Jean, Shao, Lihua, Voehringer, David, Smeal, Tod, Jallal, Bahija

“…The Aspergillus nidulans protein NIMA (never in mitosis, gene A) is a protein kinase required for the initiation of mitosis, whereas its inactivation is…”
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The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation by Hill, Ronald J, Zozulya, Sergey, Lu, Ying-Lin, Ward, Kevin, Gishizky, Mikhail, Jallal, Bahija

“…Following activation of T cells, phosphorylation of tyrosine residues occurs through a complex signaling process involving protein tyrosine kinases,…”
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