Search Results - "Jalla, Sanjoo"

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4 by Harper, Jay, Lloyd, Christopher, Dimasi, Nazzareno, Toader, Dorin, Marwood, Rose, Lewis, Leeanne, Bannister, David, Jovanovic, Jelena, Fleming, Ryan, D'Hooge, Francois, Mao, Shenlan, Marrero, Allison M, Korade, 3rd, Martin, Strout, Patrick, Xu, Linda, Chen, Cui, Wetzel, Leslie, Breen, Shannon, van Vlerken-Ysla, Lilian, Jalla, Sanjoo, Rebelatto, Marlon, Zhong, Haihong, Hurt, Elaine M, Hinrichs, Mary Jane, Huang, Keven, Howard, Philip W, Tice, David A, Hollingsworth, Robert E, Herbst, Ronald, Kamal, Adeela

“…Antibody-drug conjugates (ADC) are used to selectively deliver cytotoxic agents to tumors and have the potential for increased clinical benefit to cancer…”
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In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors by Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A, Michelotti, Emil

“…Abstract Reprogramming of energy metabolism is one of the emerging hallmarks of cancer. Up-regulation of energy metabolism pathways fuels cell growth and…”
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Abstract 1109: In vivo loss of function screening reveals carbonic anhydrase IX (CAIX) as a key modulator of tumor initiating potential in primary pancreatic tumors by Pore, Nabendu, Jalla, Sanjoo, Higgs, Brandon, Liu, Roger, Tice, David A., Hollingsworrth, Robert, Michelotti, Emil, Sorio, Claudio, Scarpa, Aldo

“…Abstract Re-programming of energy metabolism is one of the emerging hallmarks of cancer. Upregulation of energy metabolism pathways fuels cell growth and…”
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Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations by Ladd, Brendon, Mazzola, Anne Marie, Bihani, Teeru, Lai, Zhongwu, Bradford, James, Collins, Michael, Barry, Evan, Goeppert, Anne U, Weir, Hazel M, Hearne, Kelly, Renshaw, Jonathan G, Mohseni, Morvarid, Hurt, Elaine, Jalla, Sanjoo, Bao, Haifeng, Hollingsworth, Robert, Reimer, Corinne, Zinda, Michael, Fawell, Stephen, D'Cruz, Celina M

“…Although endocrine therapy is successfully used to treat patients with estrogen receptor (ER) positive breast cancer, a substantial proportion of this…”
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InVivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors12 by Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A., Michelotti, Emil

“…Reprogramming of energy metabolism is one of the emerging hallmarks of cancer. Up-regulation of energy metabolism pathways fuels cell growth and division, a…”
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InVivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors by Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A., Michelotti, Emil

“…Reprogramming of energy metabolism is one of the emerging hallmarks of cancer. Up-regulation of energy metabolism pathways fuels cell growth and division, a…”
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Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling by Michaud, Neil R, Wang, Youzhen, McEachern, Kristen A, Jordan, Jerold J, Mazzola, Anne Marie, Hernandez, Axel, Jalla, Sanjoo, Chesebrough, Jon W, Hynes, Mark J, Belmonte, Matthew A, Wang, Lidong, Kang, Jaspal S, Jovanovic, Jelena, Laing, Naomi, Jenkins, David W, Hurt, Elaine, Liang, Meina, Frantz, Christopher, Hollingsworth, Robert E, Simeone, Diane M, Blakey, David C, Bedian, Vahe

“…The hedgehog pathway has been implicated in the tumorigenesis, tumor progression, and metastasis of numerous human cancers. We generated the first fully human…”
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Abstract 948: A novel antibody-drug conjugate that induces long-term tumor regression and anticancer stem cell activity by Harper, Jay W., Lloyd, Chris, Mao, Shenlan, Lin, Xin, Dimasi, Nazzareno, Howard, Phil, O'Connor, Ellen, Farkas, David, Barton, Christopher, Smith, Jeff, Zhong, Helen, Chen, Tracy, Hinrichs, Mary Jane, Rebelatto, Marlon, Yu, Xiang-Qing, Spitz, Susan, Pierce, Andrew, Lai, Dominic, Elaine, Hurt, van Vlerken-Ysla, Lilian, Sanjoo, Jalla, Miller, Katy, McCullough, Karen, Kannan, Priya, Thompson, Simon, Mahadevia, Parthiv, Martin, Chris, Hollingsworth, Robert, Kamal, Adeela

“…Abstract Antibody-drug conjugates (ADCs) selectively deliver cytotoxic agents to tumors and provide the potential for increased clinical benefit to cancer…”
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Abstract 4587: In vitro and In vivo characterization of circulating tumor cells from breast cancer patients by Jalla, Sanjoo, Chen, Xiaoru, Burke, Patricia, Shi, Xiaoqing, Czapiga, Meggan, Datta, Vivekananda, Brohawn, Philip, Huang, Jiaqi, Brown, Charles, Hurt, Elaine, Richman, Laura, Hollingsworth, Robert, LaVallee, Theresa, Bao, Haifeng

“…Abstract Circulating tumor cells (CTCs) are an independent prognostic marker associated with poor clinical outcome in patients with metastatic diseases…”
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