Search Results - "Jalalypour, Farzaneh"

Perturb-Scan-Pull: A Novel Method Facilitating Conformational Transitions in Proteins by Jalalypour, Farzaneh, Sensoy, Ozge, Atilgan, Canan

“…Conformational transitions in proteins facilitate precise physiological functions. Therefore, it is crucial to understand the mechanisms underlying these…”
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Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS by Ilter, Metehan, Kasmer, Ramazan, Jalalypour, Farzaneh, Atilgan, Canan, Topcu, Ozan, Karakas, Nihal, Sensoy, Ozge

“…Undruggability of RAS proteins has necessitated alternative strategies for the development of effective inhibitors. In this respect, phosphorylation has…”
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Conformational multiplicity of bacterial ferric binding protein revealed by small angle x-ray scattering and molecular dynamics calculations by Liu, Goksin, Ekmen, Erhan, Jalalypour, Farzaneh, Mertens, Haydyn D T, Jeffries, Cy M, Svergun, Dmitri, Atilgan, Ali Rana, Atilgan, Canan, Sayers, Zehra

“…This study combines molecular dynamics (MD) simulations with small angle x-ray scattering (SAXS) measurements to investigate the range of conformations that…”
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A Coarse-Grained Methodology Identifies Intrinsic Mechanisms That Dissociate Interacting Protein Pairs by Abdizadeh, Haleh, Jalalypour, Farzaneh, Atilgan, Ali Rana, Atilgan, Canan

“…We address the problem of triggering dissociation events between proteins that have formed a complex. We have collected a set of 25 non-redundant, functionally…”
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Studying allosteric conformational transition in glycine receptors through protein perturbation method by Jalalypour, Farzaneh

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Comparative Evaluation of RUT, PCR and ELISA Tests for Detection of Infection with Cytotoxigenic H. pylori by Jalalypour, Farzaneh, Farajnia, Safar, Somi, Mohammad Hossein, Hojabri, Zoya, Yousefzadeh, Rana, Saeedi, Nazli

“…Purpose: Helicobacter pylori is one of the most prevalent infectious agents in the world which causes a variety of gastrointestinal diseases including…”
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Allosteric Cholesterol Site in Glycine Receptors Characterized through Molecular Simulations by Jalalypour, Farzaneh, Howard, Rebecca J., Lindahl, Erik

“…Glycine receptors are pentameric ligand-gated ion channels that conduct chloride ions across postsynaptic membranes to facilitate fast inhibitory…”
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An Allosteric Cholesterol Site in Glycine Receptors Defined Through Molecular Simulations by Jalalypour, Farzaneh, Howard, Rebecca. J., Lindahl, Erik

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Increased ionic strength triggers multiple conformations in both apo and holo forms of bacterial ferric binding protein by Atilgan, Canan, Liu, Goksin, Jalalypour, Farzaneh, Ekmen, Erhan, Berksoz, Melike, Rana Atilgan, Ali, Sayers, Zehra

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Compound heterozygous p. Arg949Trp and p. Gly970Ala mutations deteriorated the function of PEX1p: A study on PEX1 in a patient with Zellweger syndrome by Alamatsaz, Marzieh, Jalalypour, Farzaneh, Hashemi, Motahare‐Sadat, Shafeghati, Yousef, Nasr‐Esfahani, Mohammad Hossein, Ghaedi, Kamran

“…The peroxisome is responsible for a variety of vital pathways in primary metabolism, including the very long‐chain fatty‐acid oxidation and plasmalogen lipid…”
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