Search Results - "Jalalpure, Sunil S"
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System Biology Investigation Revealed Lipopolysaccharide and Alcohol-Induced Hepatocellular Carcinoma Resembled Hepatitis B Virus Immunobiology and Pathogenesis
Published in International journal of molecular sciences (01-07-2023)“…Hepatitis B infection caused by the hepatitis B virus is a life-threatening cause of liver fibrosis, cirrhosis, and hepatocellular carcinoma. Researchers have…”
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A single robust stability-indicating RP-HPLC analytical tool for apigenin quantification in bulk powder and in nanoliposomes: a novel approach
Published in Future journal of pharmaceutical sciences (16-06-2021)“…Background Apigenin (4′, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties like…”
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Molecular detection of Listeria monocytogenes from different dairy and street food sources in North Karnataka, India
Published in Journal of infection and public health (01-04-2024)“…Food-borne pathogen Listeria monocytogenes is abundantly present in nature and accountable for sporadic and epidemic cases of listeriosis in humans. The…”
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Antiurolithiatic activity of natural constituents isolated from Aerva lanata
Published in Journal of ayurveda and integrative medicine (01-10-2017)“…Pashanabheda is used as antiurolithiatic in Ayurveda. In the present study, Aerva lanata (L) Juss. ex. Schult (Amaranthaceae) from Western Ghats of India was…”
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In vitro antioxidant and anticancer activity of Leea indica leaf extracts on human prostate cancer cell lines
Published in Integrative medicine research (01-03-2017)“…To determine the phytochemical constituents, antioxidant, and anticancer activities of Leea indica leaf extracts on DU-145 and PC-3 human prostate cancer cell…”
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Pharmacoinformatics Analysis Reveals Flavonoids and Diterpenoids from Andrographis paniculata and Thespesia populnea to Target Hepatocellular Carcinoma Induced by Hepatitis B Virus
Published in Applied sciences (01-11-2022)“…Herbs are widely utilized in the Western Ghats region of India to treat liver diseases and viral-like infections. However, such practices lack scientific…”
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Antiarthritic activity of various extracts of Mesua ferrea Linn. seed
Published in Journal of ethnopharmacology (08-12-2011)“…Mesua ferrea Linn. (Cluciaseae), Cobra's saffron, is named after the heaviness of its timber and is cultivated in tropical climates for its form, foliage, and…”
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Stability studies of pure and mixture form of curcuminoids by reverse phase-HPLC method under various experimental stress conditions
Published in Food science and biotechnology (01-06-2017)“…Since time immemorial, turmeric has been widely marketed and consumed as dietary supplement due to its diverse medicinal properties. Curcuminoids—comprising a…”
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Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors
Published in Future journal of pharmaceutical sciences (07-01-2021)“…Background Tuberculosis is evidently a major health threat among human populations worldwide. The current study presents the synthesis of new…”
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Apigenin-Loaded Stealth Liposomes: Development and Pharmacokinetic Studies for Enhanced Plasma Retention of Drug in Cancer Therapy
Published in Topics in catalysis (01-01-2024)“…Apigenin belongs to the class of compounds known as flavones. It possesses significant antioxidant, anti-inflammatory, and antitumor potential in various…”
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Novel series of coumarinyl substituted-thiazolidin-2,4-dione analogs as anticancer agents: design, synthesis, spectral studies and cytotoxicity evaluation
Published in Anti-cancer agents in medicinal chemistry (01-01-2015)“…In this research work, a series of eighteen novel coumarinyl substituted thiazolidin-2,4-dione analogs (4a-4r) have been designed by molecular hybridization…”
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Antidiabetic activity of aqueous fruit extract of Cucumis trigonus Roxb. in streptozotocin-induced-diabetic rats
Published in Journal of ethnopharmacology (03-02-2010)“…The aqueous fruit extract of Cucumis trigonus has beneficial effects on serum insulin, liver glycogen level and lipid profile of STZ-induced-diabetic rats…”
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Decipher the inhibitory potential of phytocompounds from Leptadenia reticulata on dopamine D2 receptor to enhance prolactin secretion
Published in Drug research (01-04-2022)“…Dopamine is secreted by the hypothalamus, which inhibits the proliferation and effectiveness of lactotroph cells that release prolactin via dopamine D2…”
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Structural insights into modeling of hepatitis B virus reverse transcriptase and identification of its inhibitors from potential medicinal plants of Western Ghats: an in silico and in vitro study
Published in Journal of biomolecular structure & dynamics (09-12-2024)“…The present study was proposed to model full-length HBV-RT and investigate the intermolecular interactions of known inhibitor and libraries of phytocompounds…”
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A sensitive and rapid UFLC-APCI-MS/MS bioanalytical method for quantification of endogenous and exogenous Vitamin K1 isomers in human plasma: Development, validation and first application to a pharmacokinetic study
Published in Talanta (Oxford) (01-03-2017)“…Due to lack of suitable bioanalytical methods in previous literature, for simultaneous estimation of Vitamin K1 isomers, in compliance with the current…”
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Ultrasound assisted synthesis of tetrazole based pyrazolines and isoxazolines as potent anticancer agents via inhibition of tubulin polymerization
Published in Bioorganic & medicinal chemistry letters (15-11-2020)“…[Display omitted] •Ultrasound assisted method was employed for the synthesis of tetrazole based pyrazolines and isoxazolines derivatives.•Two synthesized…”
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Neuroprotective effects of photobiomodulation by hormesis on scopolamine induced neurodegenerative diseases of memory disorders in rats a paradigm shift
Published in Journal of biophotonics (01-08-2023)“…The loss and progressive dysfunction of neurons are hallmarks of neurodegenerative diseases. The aim of the current study is to explore the effects of…”
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Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids
Published in Computational biology and chemistry (01-08-2023)“…The discovery of novel chemotherapeutic agents is always challenging for researchers in industry and academia. Among the recent promising anticancer…”
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Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents
Published in Journal of biomolecular structure & dynamics (22-09-2022)“…New thiazole-thiazolidinedione hybrids (5a-k) were efficiently synthesized and evaluated for their in-vitro antimicrobial activity against four fungal and…”
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