Search Results - "Jakupaj, Muharrem"

The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus by Gjorgievska , Elizabeta S, Jakupaj , Muharrem, Leshoski , Jovica, Mladenov , Mitko, Sopi , Ramadan B, Vela , Driton, Hadzi-Petrushev , Nikola

“…Objectives: Iron overload can cause or contribute to the pathogenesis of type 2 diabetes mellitus (T2DM), but how the major parameters of iron metabolism…”
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Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine by Vela, Driton, Leshoski, Jovica, Vela, Zana, Jakupaj, Muharrem, Mladenov, Mitko, Sopi, Ramadan B

“…It has been shown that hepcidin and YKL-40 levels change in persons with insulin resistance in different circumstances. However, variations of the levels of…”
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L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia by Sopi, Ramadan B, Zaidi, Syed I A, Mladenov, Mitko, Sahiti, Hazbije, Istrefi, Zahide, Gjorgoski, Icko, Lajçi, Azem, Jakupaj, Muharrem

“…Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a…”
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Muscarinic receptor agonist‐induced constriction of airway smooth muscle is attenuated by carbon monoxide via increased cGMP production (1174.4) by Jakupaj, Muharrem, Lajçi, Azem, Temaj, Gazmend, Cenaj, Asllan, Sopi, Ramadan

“…Previously we have shown that carbon monoxide (CO) potentiates electrical field stimulation‐induced relaxation of airway smooth muscle (ASM). However, the…”
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Role of PGE 2 /EP 2 Receptor Signaling on The Effects of Neonatal Hyperoxia on Airway Smooth Muscle by Sopi, Ramadan, Mladenov, Mitko, Dreshaj, Ismail, Neziri, Burim, Mehmeti, Mirsad, Bislimi, Kemajl, Jakupaj, Muharrem

“…Abstract only It was shown that neonatal hyperoxic‐exposure associates with airway hyperresponsiveness and impaired nonadrenergic noncholinergic relaxation. It…”
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EP 1 Receptor Agonists Augment Hyperoxia‐Induced Airway Hyperresponsiveness by Sopi, Ramadan B, Neziri, Burim, Mladenov, Mitko, Vela, Driton, Lajçi, Njomza, Thaqi, Qendrim, Bislimi, Kemajl, Jakupaj, Muharrem, Lajçi, Azem

“…Abstract only Neonatal hyperoxia is associated with airway hyperresponsiveness. It was shown that hyperoxia upregulates prostaglandin E 2 synthesis, which has…”
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PGE 2 – EP 3 Receptor Signaling Involves Rho‐kinase Pathway in Hyperoxia‐Induced Airway Hyperresponsiveness by Neziri, Burim, Sopi, Ramadan B, Dreshaj, Ismail A, Beqiraj, Qendresa, Cenaj, Asllan, Kurtishi, Ilir, Krasniqi, Avdyl, Dreshaj, Shemsedin, Jakupaj, Muharrem

“…Abstract only Hyperoxic exposure is associated with airway hyperresponsiveness and it was shown that hyperoxia upregulates synthesis of prostaglandin E 2 (PGE…”
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Hematin supplementation protects against hyperoxia‐induced airway hyperresponsiveness (870.8) by Sopi, Ramadan, Zaidi, Syed, Mladenov, Mitko, Temaj, Gazmend, Sahiti, Floran, Jakupaj, Muharrem

“…It was shown that neonatal hyperoxic‐exposure associates with airway hyperresponsiveness and impaired nonadrenergic noncholinergic relaxation. Previously we…”
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Role of PGE 2 /EP 4 Receptor Signaling on The Effects of Hyperoxia on Airway Smooth Muscle by Jakupaj, Muharrem, Sopi, Ramadan, Dreshaj, Ismail, Mladenov, Mitko, Temaj, Gazmend, Cenaj, Asllan, Neziri, Burim, Beqiri, Qëndresa, Krasniqi, Avdyl

“…Abstract only It was shown that neonatal hyperoxic‐exposure associates with airway hyperresponsiveness and impaired nonadrenergic noncholinergic relaxation. It…”
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Developmental Changes in Airway Smooth Muscle Relaxation Mediated by NO and PGE2 by Jakupaj, Muharrem, Temaj, Gazmend, Cenaj, Asllan, Sopi, Ramadan B

“…Abstract only In this study we investigated changes in relaxation of airways during development and we sought to determine to what extent NO and PGE 2…”
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Hematin Supplementation Reverses the Impaired Airway Relaxation in Neonatal Rats Exposed to Hyperoxia by Sopi, Ramadan B, Zaidi, Syed IA, Bexheti, Sadi, Temaj, Gazmend, Lajçi, Azem, Jakupaj, Muharrem

“…Abstract only It was shown that hyperoxia reduces nonadrenergic noncholinergic relaxation of airway smooth muscle (ASM). Therefore, we hypothesize that…”
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Carbon Monoxide Induces Dose‐Dependent Relaxation of Airway Smooth Muscle via cGMP Signaling Pathway by Jakupaj, Muharrem, Lajçi, Azem, Bexheti, Sadi, Temaj, Gazmend, Cenaj, Asllan, Sopi, Ramadan B

“…Abstract only In present study we investigated the effect of endogenous carbon monoxide (CO) on relaxation of rat airway smooth muscle (ASM). Airway segments…”
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L‐Citrulline Protects Against Hyperoxia‐Induced Increase in Airway Contractile Responses by Sopi, Ramadan B, Mladenov, Mitko, Gjorgoski, Icko, Jakupaj, Muharrem

“…Neonatal hyperoxia increases contraction and decreases relaxation of airways in rat pups due to upregulation of arginase activity and decrease of L‐arginine…”
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The Effect of Ethanol on Tracheal Smooth Muscle During Maturation by Jakupaj, Muharrem, Sopi, Ramadan B, Krasniqi, Avdyl, Dreshaj, Ismail A

“…In previous studies we have shown that ethanol induces contraction of pulmonary artery smooth muscle in dog. Ethanol induced also contraction of tracheal…”
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Role of L‐Citrulline/L‐Arginine Cycle in Hyperoxia‐Induced Decrease of Airway Smooth Muscle Relaxation by Sopi, Ramadan, Gjorgoski, Icko, Mladenov, Mitko, Lajçi, Azem, Jakupaj, Muharrem

“…It was shown that inhibitory nonadrenergic noncholinergic (iNANC) nerve–induced nitric oxide (NO) production and airway smooth muscle (ASM) relaxation are…”
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Expression of nAChRs subunits within rostral nucleus ambigus (rNA) of ferrets by Neziri, Burim, Krasniqi, Shaip, Devaja, Shqipe, Sopi, Ramadan, Jakupaj, Muharrem

“…The role of nicotine acetylcholine receptors (nAChRs) in regulating cholinergic outflow to the airways is not fully elucidated. Furthermore, the origin of…”
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Microinjection of kynurenic acid induces airway smooth muscle relaxation in ferrets by Neziri, Burim, Krasniqi, Shaip, Jakupaj, Muharrem, Ahmetaj, Halil, Devaja, Shqipe

“…Abstract only Beside extensive study central mechanisms and neuronal networks that control airway constriction and relaxation remain unclear and poorly…”
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The Effect Of Ethanol On Tracheal Smooth Muscle Of Cat by Jakupaj, Muharrem, Sopi, Ramadan B, Lajçi, Azem, Neziri, Burim, Devaja‐Kumnova, Shqipe, Krasniqi, Avdyl

“…Previously we have shown that ethanol induces contraction of pulmonary artery smooth muscle (PASM). However, the effect of ethanol on tracheal smooth muscle…”
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Vagotomy diminished airway constriction provoked by different doses of Eserine by Jakupaj, Muharrem, Neziri, Burim, Krasniqi, Avdyl, Devaja, Shqipe

“…Although of extensive study, yet the central mechanisms involved in airway hyperractivity and bronchoconstriction remain poorly understood. In our study…”
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THE ROLE OF EPITHELIUM, THE EXTRACELLULAR Ca++ AND NO IN THE DOG TRACHEAL SMOOTH MUSCLE CONSTRICTIVE RESPONSE TO Pb ACETATE by Jakupaj, Muharrem, Neziri, Burim, Krasniqi, Avdyl

“…Epithelial cells play an important role in the regulation of the muscle tone of the airway smooth muscle (ASM). This is mediated by the local release of active…”
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