Search Results - "Jaks, Eva"
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Differential Receptor Subunit Affinities of Type I Interferons Govern Differential Signal Activation
Published in Journal of molecular biology (16-02-2007)“…Type I interferons (IFNs) elicit antiviral, antiproliferative and immunmodulatory responses by binding to a shared cell surface receptor comprising the…”
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Inquiring into the Differential Action of Interferons (IFNs): an IFN-α2 Mutant with Enhanced Affinity to IFNAR1 Is Functionally Similar to IFN-β
Published in Molecular and Cellular Biology (01-03-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inquiring into the Differential Action of Interferons (IFNs): an IFN- alpha 2 Mutant with Enhanced Affinity to IFNAR1 Is Functionally Similar to IFN- beta
Published in Molecular and cellular biology (01-03-2006)“…Alpha and beta interferons (IFN- alpha and IFN- beta ) are multifunctional cytokines that exhibit differential activities through a common receptor composed of…”
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4
Determination of the Two-Dimensional Interaction Rate Constants of a Cytokine Receptor Complex
Published in Biophysical journal (01-05-2006)“…Ligand-receptor interactions within the plane of the plasma membrane play a pivotal role for transmembrane signaling. The biophysical principles of…”
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Ligand Binding Induces a Conformational Change in ifnar1 that Is Propagated to Its Membrane-Proximal Domain
Published in Journal of molecular biology (28-03-2008)“…The type I interferon (IFN) receptor plays a key role in innate immunity against viral and bacterial infections. Here, we show by intramolecular Förster…”
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Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta
Published in Molecular and cellular biology (01-03-2006)“…Alpha and beta interferons (IFN-alpha and IFN-beta) are multifunctional cytokines that exhibit differential activities through a common receptor composed of…”
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Journal Article