Search Results - "Jakoi, L"

A combinatorial mechanism for determining the specificity of E2F activation and repression by Freedman, J A, Chang, J T, Jakoi, L, Nevins, J R

“…Various studies have detailed the role of E2F proteins in both transcription activation and repression. Further study has shown that distinct promoter…”
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The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state by Smith, Eric J., Leone, Gustavo, DeGregori, James, Jakoi, Laszlo, Nevins, Joseph R.

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A Unique Role for the Rb Protein in Controlling E2F Accumulation during Cell Growth and Differentiation by Ikeda, Masa-Aki, Jakoi, Laszlo, Nevins, Joseph R.

“…Examination of the interactions involving transcription factor E2F activity during cell growth and terminal differentiation suggests distinct roles for Rb…”
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Oncogenic Capacity of the E2F1 Gene by Johnson, David G., Cress, W. Douglas, Jakoi, Laszlo, Nevins, Joseph R.

“…Previous experiments have identified the E2F transcription factor as a potential downstream target for the action of cellular regulatory activities, such as…”
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Interactions of the p107 and Rb proteins with E2F during the cell proliferation response by Schwarz, J.K., Devoto, S.H., Smith, E.J., Chellappan, S.P., Jakoi, L., Nevins, J.R.

“…The E2F transcription factor is found in complexes with a variety of cellular proteins including the retinoblastoma tumor suppressor protein. Various assays…”
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The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding by Yee, A S, Raychaudhuri, P, Jakoi, L, Nevins, J R

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Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants by Verghese, MW, Charles, L, Jakoi, L, Dillon, SB, Snyderman, R

“…It is well established that formyl peptide chemoattractants can activate a phospholipase C in leukocytes via a pertussis toxin (PT)-sensitive guanine…”
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Identification and Characterization of E2F7, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation by de Bruin, Alain, Maiti, Baidehi, Jakoi, Laszlo, Timmers, Cynthia, Buerki, Robin, Leone, Gustavo

“…The mammalian E2F family of transcription factors plays a crucial role in the regulation of cellular proliferation, apoptosis, and differentiation. Consistent…”
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Distinct Roles for E2F Proteins in Cell Growth Control and Apoptosis by DeGregori, James, Leone, Gustavo, Miron, Alexander, Jakoi, Laszlo, Nevins, Joseph R.

“…E2F transcription activity is composed of a family of heterodimers encoded by distinct genes. Through the overproduction of each of the five known E2F proteins…”
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Biochemical and Functional Responses Stimulated by Platelet-Activating Factor in Murine Peritoneal Macrophages by Prpic, Veronica, Uhing, Ronald J., Weiel, James E., Jakoi, Lazlo, Gawdi, Govind, Herman, Brian, Adams, Dolph O.

“…Platelet-activating factor (PAF) is a potent stimulant of leukocytes, including macrophages. To analyze the mechanisms of its effects upon macrophages, we…”
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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase by Leone, G, DeGregori, J, Yan, Z, Jakoi, L, Ishida, S, Williams, R S, Nevins, J R

“…Previous work has demonstrated the important role of E2F transcription activity in the induction of S phase during the transition from quiescence to…”
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E2F4 and E2F5 Play an Essential Role in Pocket Protein–Mediated G1 Control by Gaubatz, Stefan, Lindeman, Geoffrey J., Ishida, Seiichi, Jakoi, Laszlo, Nevins, Joseph R., Livingston, David M., Rempel, Rachel E.

“…E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual members perform distinct…”
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Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F by Leone, Gustavo, DeGregori, James, Sears, Rosalie, Jakoi, Laszlo, Nevins, Joseph R

“…Considerable evidence points to a role for G1 cyclin-dependent kinase (CDK) in allowing the accumulation of E2F transcription factor activity and induction of…”
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Leukocyte Chemoattraction by 1,2-diacylglycerol by Wright, Timothy M., Hoffman, Robert D., Nishijima, Junichi, Jakoi, Laszlo, Snyderman, Ralph, Shin, Hyun S.

“…Previous reports have demonstrated the hydrolysis of inositol phospholipids in polymorphonuclear leukocytes (PMN) in response to chemoattractants and in…”
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Chemoattractant-mediated stimulation of the respiratory burst in human polymorphonuclear leukocytes may require appearance of protein kinase activity in the cells' particulate fraction by Pike, MC, Jakoi, L, McPhail, LC, Snyderman, R

“…Low doses of aliphatic alcohols produce divergent effects on the function of chemoattractant receptors on human polymorphonuclear leukocytes (PMNs) since they…”
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Identification of a Novel E2F3 Product Suggests a Mechanism for Determining Specificity of Repression by Rb Proteins by Leone, Gustavo, Nuckolls, Faison, Ishida, Seiichi, Adams, Monique, Sears, Rosalie, Jakoi, Laszlo, Miron, Alexander, Nevins, Joseph R.

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Role of the Rb/E2F pathway in cell growth control by Nevins, Joseph R., Leone, Gustavo, DeGregori, James, Jakoi, Laszlo

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Loss of E2F4 Activity Leads to Abnormal Development of Multiple Cellular Lineages by Rempel, Rachel E., Saenz-Robles, M.Teresa, Storms, Robert, Morham, Scott, Ishida, Seiichi, Engel, Amber, Jakoi, Laszlo, Melhem, Mona F., Pipas, James M., Smith, Clay, Nevins, Joseph R.

“…We have generated mice deficient in E2F4 activity, the major form of E2F in many cell types. Analysis of newborn pups deficient in E2F4 revealed abnormalities…”
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The sources of rat biliary cholesterol and bile acid by Long, T T, Jakoi, L, Stevens, R, Quarfordt, S

“…The precursor sources of bile acid and bile neutral sterol were evaluated in the rat using Triparanol to inhibit the terminal reduction in the synthesis of…”
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Alterations of rat hepatic cholesterogenesis by heterologous lipoproteins by Jakoi, L, Quarfordt, S H

“…Heterologous human lipoproteins were infused into rats in order to change acutely the lipoprotein pattern to a predominant kind and the effect on hepatic…”
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