Search Results - "Jakobsson, T."

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types by Häring, Martin, Zeisel, Amit, Hochgerner, Hannah, Rinwa, Puneet, Jakobsson, Jon E. T., Lönnerberg, Peter, La Manno, Gioele, Sharma, Nilesh, Borgius, Lotta, Kiehn, Ole, Lagerström, Malin C., Linnarsson, Sten, Ernfors, Patrik

“…The dorsal horn of the spinal cord is critical to processing distinct modalities of noxious and innocuous sensation, but little is known of the neuronal…”
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Spinal gastrin releasing peptide receptor expressing interneurons are controlled by local phasic and tonic inhibition by Freitag, Fabio B., Ahemaiti, Aikeremu, Jakobsson, Jon E. T., Weman, Hannah M., Lagerström, Malin C.

“…Dorsal horn gastrin-releasing peptide receptor (GRPR) neurons have a central role in itch transmission. Itch signaling has been suggested to be controlled by…”
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Single Cell Transcriptomic Analysis of Spinal Dmrt3 Neurons in Zebrafish and Mouse Identifies Distinct Subtypes and Reveal Novel Subpopulations Within the dI6 Domain by Iglesias González, Ana Belén, Jakobsson, Jon E T, Vieillard, Jennifer, Lagerström, Malin C, Kullander, Klas, Boije, Henrik

“…The spinal locomotor network is frequently used for studies into how neuronal circuits are formed and how cellular activity shape behavioral patterns. A…”
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Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice by González-Granillo, M., Steffensen, K. R., Granados, O., Torres, N., Korach-André, M., Ortíz, V., Aguilar-Salinas, C., Jakobsson, T., Díaz-Villaseñor, A., Loza-Valdes, A., Hernandez-Pando, R., Gustafsson, J.-Å., Tovar, A. R.

“…Aims/hypothesis Liver X receptor (LXR)α regulates the genes involved in cholesterol, fatty acid and glucose metabolism. Soy protein (SP) consumption reduces…”
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Clinical performance of a levonorgestrel-releasing intrauterine system and oral contraceptives in young nulliparous women: a comparative study by Suhonen, Satu, Haukkamaa, Maija, Jakobsson, Tell, Rauramo, Ilkka

“…This 1-year randomized study was carried out at family-planning clinics of two university hospitals to compare the safety and acceptability of a…”
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The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice by Jakobsson, T, Vedin, L-L, Hassan, T, Venteclef, N, Greco, D, D'Amato, M, Treuter, E, Gustafsson, J-Å, Steffensen, K R

“…We examined the function of the oxysterol receptors (LXRs) in inflammatory bowel disease (IBD) through studying dextran sodium sulfate (DSS)- and…”
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Late miscarriage and preterm birth after treatment with clindamycin: a randomised consent design study according to Zelen by Larsson, P‐G, Fåhraeus, L, Carlsson, B, Jakobsson, T, Forsum, U

“…Objective  To screen for bacterial vaginosis (BV) and to investigate the effect of treatment with vaginal clindamycin in order to observe the effect on late…”
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Bacterial vaginosis - a microbiological and immunological enigma by FORSUM, U., HOLST, E., LARSSON, P. G., VASQUEZ, A., JAKOBSSON, T., MATTSBY-BALTZER, I.

“…The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring…”
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Influence of land use on the abundance of wildlife and livestock in the Kalahari, Botswana by Wallgren, M., Skarpe, C., Bergström, R., Danell, K., Bergström, A., Jakobsson, T., Karlsson, K., Strand, T.

“…Human land use such as pastoralism may be a key determinant of wildlife populations. We studied the influence of land use on wildlife and livestock in…”
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Neuropeptide Y in itch regulation by Jakobsson, Jon E.T., Ma, Haisha, Lagerström, Malin C.

“…Itch is a somatosensory sensation that informs the organism about the presence of potentially harmful substances or parasites, and initiates scratching to…”
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Probiotics in the Prevention of IgE-Associated Eczema: a Double Blind Randomised Placebo-Controlled Trial by Abrahamsson, T, Jakobsson, T, Fagerås Böttcher, M, Fredrikson, M, Jenmalm, M.C, Björkstén, B, Oldaeus, G

“…Primary outcome was allergic disease, with or without positive skin prick test or circulating IgE to food allergens…”
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Diagnosis of bacterial vaginosis: need for validation of microscopic image area used for scoring bacterial morphotypes by Larsson, P-G, Carlsson, B, Fåhraeus, L, Jakobsson, T, Forsum, U

“…Background: The diagnosis of bacterial vaginosis (BV) is often made according to Nugent’s classification, a scoring system based on bacterial counting of Gram…”
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An international study of the interobserver variation between interpretations of vaginal smear criteria of bacterial vaginosis by FORSUM, U., JAKOBSSON, T., LARSSON, P. G., SCHMIDT, H., BEVERLY, A., BJØRNEREM, A., CARLSSON, B., CSANGO, P., DONDERS, G., HAY, P., ISON, C., KEANE, F., McDONALD, H., MOI, H., PLATZ-CHRISTENSEN, J.-J., SCHWEBKE, J.

“…An international workshop on vaginal smear‐based diagnosis of bacterial vaginosis was organized where 13 investigators scoring 258 slides with smears from…”
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scConnect: a method for exploratory analysis of cell–cell communication based on single-cell RNA-sequencing data by Jakobsson, Jon E T, Spjuth, Ola, Lagerström, Malin C

“…Abstract Motivation Cell to cell communication is critical for all multicellular organisms, and single-cell sequencing facilitates the construction of full…”
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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities by Jakobsson, Tomas, Treuter, Eckardt, Gustafsson, Jan-Åke, Steffensen, Knut R

“…Nuclear receptors (NRs) are master regulators of transcriptional programs that integrate the homeostatic control of almost all biological processes. Their…”
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Transcriptional repression in macrophages—basic mechanisms and alterations in metabolic inflammatory diseases by Treuter, Eckardt, Fan, Rongrong, Huang, Zhiqiang, Jakobsson, Tomas, Venteclef, Nicolas

“…Macrophage differentiation and signal responses are coordinated by closely linked transcriptional and epigenomic mechanisms that trigger gene expression. In…”
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Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia by Jakobsson, Tomas, Vedin, Lise-Lotte, Parini, Paolo

“…Thyroid hormones have important effects on cellular development, growth, and metabolism and are necessary for the healthy function of almost all tissues…”
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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages by Huang, Zhiqiang, Liang, Ning, Goñi, Saioa, Damdimopoulos, Anastasios, Wang, Cheng, Ballaire, Raphaelle, Jager, Jennifer, Niskanen, Henri, Han, Hongya, Jakobsson, Tomas, Bracken, Adrian P., Aouadi, Myriam, Venteclef, Nicolas, Kaikkonen, Minna U., Fan, Rongrong, Treuter, Eckardt

“…While the role of transcription factors and coactivators in controlling enhancer activity and chromatin structure linked to gene expression is well…”
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Metabolic nuclear receptor signaling and the inflammatory acute phase response by Venteclef, Nicolas, Jakobsson, Tomas, Steffensen, Knut R, Treuter, Eckardt

“…The acute phase response (APR) classically refers to the rapid reprogramming of gene expression and metabolism in response to inflammatory cytokine signaling…”
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The Nuclear Receptor-Co-repressor Complex in Control of Liver Metabolism and Disease by Liang, Ning, Jakobsson, Tomas, Fan, Rongrong, Treuter, Eckardt

“…Hepatocytes are the major cell-type in the liver responsible for the coordination of metabolism in response to multiple signaling inputs. Coordination occurs…”
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