Search Results - "Jakobs, A"

KymoButler, a deep learning software for automated kymograph analysis by Jakobs, Maximilian A H, Dimitracopoulos, Andrea, Franze, Kristian

“…Kymographs are graphical representations of spatial position over time, which are often used in biology to visualise the motion of fluorescent particles,…”
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Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation by Jakobs, Maximilian AH, Zemel, Assaf, Franze, Kristian

“…In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on…”
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An isoform-specific C/EBPβ inhibitor targets acute myeloid leukemia cells by Jakobs, A, Uttarkar, S, Schomburg, C, Steinmann, S, Coulibaly, A, Schlenke, P, Berdel, W E, Müller-Tidow, C, Schmidt, T J, Klempnauer, K-H

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Untersuchungen zu potenziellen protektiven Effekten von Apfelsaftinhaltsstoffen auf die Darmbarriere by Köpsel, M., Jakobs, A.‐L., Esatbeyoglu, T.

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Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons by Cioni, Jean-Michel, Lin, Julie Qiaojin, Holtermann, Anne V., Koppers, Max, Jakobs, Maximilian A.H., Azizi, Afnan, Turner-Bridger, Benita, Shigeoka, Toshiaki, Franze, Kristian, Harris, William A., Holt, Christine E.

“…Local translation regulates the axonal proteome, playing an important role in neuronal wiring and axon maintenance. How axonal mRNAs are localized to specific…”
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Mechanical Regulation of Neurite Polarization and Growth: A Computational Study by Jakobs, Maximilian A.H., Franze, Kristian, Zemel, Assaf

“…The densely packed microtubule (MT) array found in neuronal cell projections (neurites) serves two fundamental functions simultaneously: it provides a…”
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Mutation of the ALS-/FTD-Associated RNA-Binding Protein FUS Affects Axonal Development by van Tartwijk, Francesca W, Wunderlich, Lucia C S, Mela, Ioanna, Makarchuk, Stanislaw, Jakobs, Maximilian A H, Qamar, Seema, Franze, Kristian, Kaminski Schierle, Gabriele S, St George-Hyslop, Peter H, Lin, Julie Qiaojin, Holt, Christine E, Kaminski, Clemens F

“…Aberrant condensation and localization of the RNA-binding protein (RBP) fused in sarcoma (FUS) occur in variants of amyotrophic lateral sclerosis (ALS) and…”
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Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons by Koppers, Max, Cagnetta, Roberta, Shigeoka, Toshiaki, Wunderlich, Lucia Cs, Vallejo-Ramirez, Pedro, Qiaojin Lin, Julie, Zhao, Sixian, Jakobs, Maximilian Ah, Dwivedy, Asha, Minett, Michael S, Bellon, Anaïs, Kaminski, Clemens F, Harris, William A, Flanagan, John G, Holt, Christine E

“…Extrinsic cues trigger the local translation of specific mRNAs in growing axons via cell surface receptors. The coupling of ribosomes to receptors has been…”
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Comparison between multiple trapping and multiple hopping transport in a random medium by Hartenstein, B, Bässler, H, Jakobs, A, Kehr, KW

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1-Thiomethoxsalen and 1-Thiopsoralen: Synthesis, Photobiological Properties, and Site Specific Reaction of Thiopsoralens with DNA by Jakobs, Andreas E, Piette, Jacques

“…The sulfur analogues of psoralen and 8-methoxypsoralen (8-MOP) in the pyrone moiety were synthesized and compared to the parent compounds in terms of…”
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Estimating the uncertainty of the greenhouse gas emission accounts in global multi-regional input-output analysis by Schulte, Simon, Jakobs, Arthur, Pauliuk, Stefan

“…Global multi-regional input-output (GMRIO) analysis is the standard tool to calculate consumption-based carbon accounts at the macro level. Recent…”
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Monensin, a novel potent MYB inhibitor, suppresses proliferation of acute myeloid leukemia and adenoid cystic carcinoma cells by Yusenko, Maria V., Trentmann, Amke, Andersson, Mattias K., Ghani, Luca Abdel, Jakobs, Anke, Arteaga Paz, Mari-Francis, Mikesch, Jan-Henrik, Peter von Kries, Jens, Stenman, Göran, Klempnauer, Karl-Heinz

“…The master transcriptional regulator MYB is a key oncogenic driver in several human neoplasms, particularly in acute myeloid leukemia (AML) and adenoid cystic…”
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Geothermal Energy: a glimpse at the state of the field and an introduction to the journal by Kolditz, Olaf, Jakobs, Leslie A, Huenges, Ernst, Kohl, Thomas

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Electron Spin Resonance Evidence of the Generation of Superoxide Anion, Hydroxyl Radical and Singlet Oxygen during the Photohemolysis of Human Erythrocytes with Bacteriochlorin a by Hoebeke, Maryse, Schuitmaker, Hans J., Jannink, Lies E., Dubbelman, Tom M. A. R., Jakobs, Andreas, Van de Vorst, Albert

“…— Photodynamic therapy with bacteriochlorin a (BCA) as sensitizer induces damage to red blood cells in vivo. To assess the extent of the contributuion of…”
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Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial by VERMEULEN, E. G. J, STEHOUWER, C. D. A, RAUWERDA, J. A, TWISK, J. W. R, VAN DEN BERG, M, DE JONG, S. C, MACKAAY, A. J. C, VAN CAMPEN, C. M. C, VISSER, F. C, JAKOBS, C. A. J. M, BULTERIJS, E. J

“…A high plasma homocysteine concentration is associated with increased risk of atherothrombotic disease. We investigated the effects of homocysteine-lowering…”
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Photosensitized generation of hydroxyl radical by eight new sulfur and selenium analogs of psoralen by Collet, M., Hoebeke, M., Piette, J., Jakobs, A., Lindqvist, L., Van de Vorst, A.

“…Using spin-trapping with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) combined with electron spin resonance spectroscopy (ESR), irradiation at the PUVA wavelength…”
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An isoform-specific C/EBP[beta] inhibitor targets acute myeloid leukemia cells by Berdel, W E, Uttarkar, S, Jakobs, A, Schomburg, C, Steinmann, S, Coulibaly, A, Schlenke, P

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Optimization of the waveguide properties for ZnSe laser diodes by Jakobs, A., Hommel, D., Landwehr, G.

“…We present numerical calculations to optimize the wave guiding properties of ZnSe based laser structures. Herein we not only focus on the actual waveguide…”
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Microtubule Polarity in Axons is Sorted by a Molecular Gradient of Dynactin by Jakobs, Maximilian A., Franze, Kristian

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Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini by de Pont, J.J.H.H.M., Fleuren-Jakobs, A.M.M.

“…The combination of the ionophore A23187 and the phorbol ester 12- O-tetradecanoyl-phorbol-13-acetate (TPA) stimulates amylase secretion from rabbit pancreatic…”
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