Search Results - "Jakieła, Bogdan"

Editorial to the Special Issue "Pathogenesis and Novel Therapeutics in Asthma" by Bazan-Socha, Stanisława, Jakieła, Bogdan

“…In recent years, substantial progress has been made in our understanding of asthma pathomechanisms, especially phenotyping [...]…”
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Cellular immune response to SARS-CoV-2 in patients with primary antibody deficiencies by Mizera, Dorota, Dziedzic, Radosław, Drynda, Anna, Gradzikiewicz, Ada, Jakieła, Bogdan, Celińska-Löwenhoff, Magdalena, Padjas, Agnieszka, Matyja-Bednarczyk, Aleksandra, Zaręba, Lech, Bazan-Socha, Stanisława

“…Introduction Primary antibody deficiencies (PAD) are inborn defects of the immune system that result in increased susceptibility to infections. Despite the…”
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Omalizumab may decrease the thickness of the reticular basement membrane and fibronectin deposit in the bronchial mucosa of severe allergic asthmatics by Zastrzeżyńska, Weronika, Przybyszowski, Marek, Bazan-Socha, Stanisława, Gawlewicz-Mroczka, Agnieszka, Sadowski, Piotr, Okoń, Krzysztof, Jakieła, Bogdan, Plutecka, Hanna, Ćmiel, Adam, Sładek, Krzysztof, Musiał, Jacek, Soja, Jerzy

“…Introduction: Immunoglobulin E is an important modulator of the inflammatory reaction in allergic asthma. It also contributes to airway remodeling in the…”
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Increased Oxidative Stress in Asthma-Relation to Inflammatory Blood and Lung Biomarkers and Airway Remodeling Indices by Bazan-Socha, Stanisława, Wójcik, Krzysztof, Olchawa, Magdalena, Sarna, Tadeusz, Pięta, Jakub, Jakieła, Bogdan, Soja, Jerzy, Okoń, Krzysztof, Zarychta, Jacek, Zaręba, Lech, Stojak, Michał, Potaczek, Daniel P, Bazan, Jan G, Celińska-Lowenhoff, Magdalena

“…Airway inflammation in asthma is related to increased reactive oxygen species generation, potentially leading to tissue injury and subsequent airway…”
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Responsiveness of human bronchial fibroblasts and epithelial cells from asthmatic and non-asthmatic donors to the transforming growth factor-β1 in epithelial-mesenchymal trophic unit model by Paw, Milena, Wnuk, Dawid, Jakieła, Bogdan, Bochenek, Grażyna, Sładek, Krzysztof, Madeja, Zbigniew, Michalik, Marta

“…Abstract Background The asthma-related airway wall remodeling is associated i.a. with a damage of bronchial epithelium and subepithelial fibrosis. Functional…”
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Regulation of bronchial epithelial barrier integrity by type 2 cytokines and histone deacetylases in asthmatic patients by Wawrzyniak, Paulina, MSc, Wawrzyniak, Marcin, PhD, Wanke, Kerstin, PhD, Sokolowska, Milena, MD, PhD, Bendelja, Kreso, PhD, Rückert, Beate, Sci Tec, Globinska, Anna, MSc, Jakiela, Bogdan, MD, PhD, Kast, Jeannette I., MSc, Idzko, Marco, MD, Akdis, Mübeccel, MD, PhD, Sanak, Marek, MD, PhD, Akdis, Cezmi A., MD

“…Background Tight junctions (TJs) form a barrier on the apical side of neighboring epithelial cells in the bronchial mucosa. Changes in their integrity might…”
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Sputum transcriptome analysis of co‐regulated genes related to arachidonic acid metabolism in N‐ERD by Mastalerz, Lucyna, Kacorzyk, Radosław, Jakieła, Bogdan, Ćmiel, Adam, Sanak, Marek

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Remodeling of bronchial epithelium caused by asthmatic inflammation affects its response to rhinovirus infection by Jakiela, Bogdan, Rebane, Ana, Soja, Jerzy, Bazan-Socha, Stanislawa, Laanesoo, Anet, Plutecka, Hanna, Surmiak, Marcin, Sanak, Marek, Sladek, Krzysztof, Bochenek, Grazyna

“…Human rhinoviruses (HRV) are frequent cause of asthma exacerbations, however the influence of airway inflammation on the severity of viral infection is poorly…”
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Aspirin hypersensitivity diagnostic index (AHDI): In vitro test for diagnosing of N-ERD based on urinary 15-oxo-ETE and LTE4 excretion by Mastalerz, Lucyna, Trąd, Gabriela, Szatkowski, Piotr, Ćmiel, Adam, Gielicz, Anna, Kacorzyk, Radosław, Plutecka, Hanna, Szaleniec, Joanna, Gawlewicz-Mroczka, Agnieszka, Jakieła, Bogdan, Sanak, Marek

“…15-oxo-eicosatetraenoic acid (15-oxo-ETE), is a product of arachidonic acid (AA) metabolism in the 15-lipoxygenase-1 (15-LOX-1) pathway. 15-oxo-ETE was…”
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Skewing toward Treg and Th2 responses is a characteristic feature of sustained remission in ANCA‐positive granulomatosis with polyangiitis by Szczeklik, Wojciech, Jakieła, Bogdan, Wawrzycka‐Adamczyk, Katarzyna, Sanak, Marek, Hubalewska‐Mazgaj, Magdalena, Padjas, Agnieszka, Surmiak, Marcin, Szczeklik, Katarzyna, Sznajd, Jan, Musiał, Jacek

“…The objective of our study was to evaluate the T‐helper (Th) and regulatory T (Treg) cell profile in ANCA‐positive granulomatosis with polyangiitis (GPA) and…”
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Increased production of IL-5 and dominant Th2-type response in airways of Churg―Strauss syndrome patients by JAKIELA, Bogdan, SZCZEKLIK, Wojciech, PLUTECKA, Hanna, SOKOLOWSKA, Barbara, MASTALERZ, Lucyna, SANAK, Marek, BAZAN-SOCHA, Stanislawa, SZCZEKLIK, Andrzej, MUSIAL, Jacek

“…Churg-Strauss syndrome (CSS) is a rare systemic vasculitis associated with eosinophilia and asthma. We assessed the local immune response in airways of CSS…”
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Increased oxidative stress response in circulating blood of systemic sclerosis patients – relation to disease characteristics and inflammatory blood biomarkers by Dziedzic, Radosław, Wójcik, Krzysztof, Olchawa, Magdalena, Sarna, Tadeusz, Pięta, Jakub, Jakieła, Bogdan, Padjas, Agnieszka, Korona, Anna, Zaręba, Lech, Potaczek, Daniel P., Kosałka-Węgiel, Joanna, Jurczyszyn, Artur, Bazan-Socha, Stanisława

“…Systemic sclerosis (SSc) is a rare connective tissue disorder of unknown etiology characterized by organ fibrosis and microcirculation dysfunction. Emerging…”
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Connective tissue growth factor regulates transition of primary bronchial fibroblasts to myofibroblasts in asthmatic subjects by Wójcik-Pszczoła, Katarzyna, Jakieła, Bogdan, Plutecka, Hanna, Koczurkiewicz, Paulina, Madeja, Zbigniew, Michalik, Marta, Sanak, Marek

“…[Display omitted] •CTGF contributes to fibroblasts-to-myofibroblasts transition in bronchial asthma.•TGF-β1-induced FMT in bronchial fibroblasts of asthmatics…”
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Biomarkers for predicting response to aspirin therapy in aspirin‐exacerbated respiratory disease by Tyrak, Katarzyna E., Pajdzik, Kinga, Jakieła, Bogdan, Kupryś‐Lipińska, Izabela, Ćmiel, Adam, Kacorzyk, Radosław, Trąd, Gabriela, Kuna, Piotr, Sanak, Marek, Mastalerz, Lucyna

“…Background Aspirin desensitization followed by daily aspirin use is an effective treatment for aspirin‐exacerbated respiratory disease (AERD). Objective To…”
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Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19 by Radzikowska, Urszula, Eljaszewicz, Andrzej, Tan, Ge, Stocker, Nino, Heider, Anja, Westermann, Patrick, Steiner, Silvio, Dreher, Anita, Wawrzyniak, Paulina, Rückert, Beate, Rodriguez-Coira, Juan, Zhakparov, Damir, Huang, Mengting, Jakiela, Bogdan, Sanak, Marek, Moniuszko, Marcin, O’Mahony, Liam, Jutel, Marek, Kebadze, Tatiana, Jackson, David J., Edwards, Michael R., Thiel, Volker, Johnston, Sebastian L., Akdis, Cezmi A., Sokolowska, Milena

“…Rhinoviruses and allergens, such as house dust mite are major agents responsible for asthma exacerbations. The influence of pre-existing airway inflammation on…”
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CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier by Kubo, Terufumi, MD, PhD, Wawrzyniak, Paulina, MSc, Morita, Hideaki, MD, PhD, Sugita, Kazunari, MD, PhD, Wanke, Kerstin, PhD, Kast, Jeannette I., MSc, Altunbulakli, Can, MSc, Rückert, Beate, Sci Tec, Jakiela, Bogdan, PhD, Sanak, Marek, MD, PhD, Akdis, Mübeccel, MD, PhD, Akdis, Cezmi A., MD

“…[...]bronchial epithelial cells are at the forefront of tissue defense and the innate immune response, preventing invasion of tissues as a physical barrier…”
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miR-200b downregulates CFTR during hypoxia in human lung epithelial cells by Bartoszewska, Sylwia, Kamysz, Wojciech, Jakiela, Bogdan, Sanak, Marek, Króliczewski, Jarosław, Bebok, Zsuzsa, Bartoszewski, Rafal, Collawn, James F

“…Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a…”
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Effect of omalizumab on bronchoalveolar lavage matrix metalloproteinases in severe allergic asthma by Zastrzeżyńska, Weronika, Bazan-Socha, Stanisława, Przybyszowski, Marek, Gawlewicz-Mroczka, Agnieszka, Jakieła, Bogdan, Plutecka, Hanna, Zaręba, Lech, Musiał, Jacek, Okoń, Krzysztof, Sładek, Krzysztof, Soja, Jerzy

“…Airway inflammation in asthma is accompanied by reconstruction of the bronchial wall extracellular matrix that most likely occurs with a contribution of matrix…”
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Reticular Basement Membrane Thickness Is Associated with Growth- and Fibrosis-Promoting Airway Transcriptome Profile-Study in Asthma Patients by Bazan-Socha, Stanislawa, Buregwa-Czuma, Sylwia, Jakiela, Bogdan, Zareba, Lech, Zawlik, Izabela, Myszka, Aleksander, Soja, Jerzy, Okon, Krzysztof, Zarychta, Jacek, Kozlik, Paweł, Dziedzina, Sylwia, Padjas, Agnieszka, Wojcik, Krzysztof, Kepski, Michal, Bazan, Jan G

“…Airway remodeling in asthma is characterized by reticular basement membrane (RBM) thickening, likely related to epithelial structural and functional changes…”
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A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illnesses in infants by Lee, Wai-Ming, Kiesner, Christin, Pappas, Tressa, Lee, Iris, Grindle, Kris, Jartti, Tuomas, Jakiela, Bogdan, Lemanske, Jr, Robert F, Shult, Peter A, Gern, James E

“…Human rhinoviruses (HRVs) are the most prevalent human pathogens, and consist of 101 serotypes that are classified into groups A and B according to sequence…”
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