Search Results - "Jakas, Andreja"
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New Levan-Based Chiral Stationary Phases: Synthesis and Comparative HPLC Enantioseparation of (±)- trans -β-Lactam Ureas in the Polar Organic Mode
Published in Molecules (Basel, Switzerland) (09-05-2024)“…In this paper, the preparation of three new polysaccharide-type chiral stationary phases (CSPs) based on levan carbamates (3,5-dimethylphenyl, 4-methylphenyl,…”
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Synthesis of Glycomimetics by Diastereoselective Passerini Reaction
Published in Journal of organic chemistry (02-11-2018)“…We describe the utilization of bis-isopropylidene-protected d-fructose-derived aldehyde in the Passerini reaction with various acids and isocyanides. A library…”
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Adsorption/Desorption of Cationic-Hydrophobic Peptides on Zwitterionic Lipid Bilayer Is Associated with the Possibility of Proton Transfer
Published in Antibiotics (Basel) (01-07-2023)“…Cell-penetrating peptides (CPPs) are short peptides built up from dominantly cationic and hydrophobic amino acid residues with a distinguished ability to pass…”
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Synthesis, Absolute Configuration, Biological Profile and Antiproliferative Activity of New 3,5-Disubstituted Hydantoins
Published in Pharmaceuticals (Basel, Switzerland) (24-09-2024)“…Hydantoins, a class of five-membered heterocyclic compounds, exhibit diverse biological activities. The aim of this study was to synthesize and characterize a…”
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Application of Biotechnology and Chiral Technology Methods in the Production of Ectoine Enantiomers
Published in Applied sciences (01-09-2024)“…Natural ectoine, (+)-(4S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, is an extremely important small biomolecule belonging to the class of…”
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Synthesis of Orthogonally Protected Muramic Acid Building Blocks for Solid Phase Peptide Synthesis
Published in Croatica Chemica Acta (01-07-2015)“…Muramic acid is found in many peptide natural products containing oligo(poly)saccharide moieties. Taking into consideration that the Fmoc methodology is…”
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The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers
Published in IUCrJ (01-03-2017)“…Peptidoglycan is a giant molecule that forms the cell wall that surrounds bacterial cells. It is composed of alternating -acetylglucosamine (NAG) and…”
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Metal-Binding Ability of Leu-Enkephalin, Related Glycoconjugates and Peptidomimetics
Published in Croatica Chemica Acta (01-07-2015)“…Both the chemistry and consequences of the nonenzymatic reaction between reducing sugars and reactive amino groups of amino acids, peptides and proteins (known…”
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Structure analysis of proteins, peptides and metal complexes by vibrational circular dichroism
Published in ARKIVOC (08-06-2012)Get full text
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10
Amadori and Heyns rearrangement products of bioactive peptides as potential new ligands of galectin-3
Published in Carbohydrate research (01-08-2024)“…Non-enzymatic cascade reactions between amines and reducing sugars are known as Maillard reaction. The late phase of these reactions consists of advanced…”
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New Levan-Based Chiral Stationary Phases: Synthesis and Comparative HPLC Enantioseparation of -Itrans/I-β-Lactam Ureas in the Polar Organic Mode
Published in Molecules (Basel, Switzerland) (01-05-2024)“…In this paper, the preparation of three new polysaccharide-type chiral stationary phases (CSPs) based on levan carbamates (3,5-dimethylphenyl, 4-methylphenyl,…”
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Multicomponent reaction derived small di- and tri-carbohydrate-based glycomimetics as tools for probing lectin specificity
Published in Glycoconjugate journal (01-10-2022)“…Lectins, carbohydrate-binding proteins, play important functions in all forms of life from bacteria and viruses to plants, animals, and humans, participating…”
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Multicomponent Approach to Homo- and Hetero-Multivalent Glycomimetics Bearing Rare Monosaccharides
Published in Journal of organic chemistry (06-03-2020)“…We applied a multicomponent approach to access a library of densely functionalized homo- and hetero-multivalent glycomimetics comprising aldehyde, amine, and…”
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Synthesis and biological evaluation of quercetin and resveratrol peptidyl derivatives as potential anticancer and antioxidant agents
Published in Amino acids (01-02-2019)“…Quercetin and resveratrol are polyphenolic compounds, members of the flavonoid and the stilbene family, respectively, both medicinally important as dietary…”
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Design and synthesis of novel antimicrobial peptide scaffolds
Published in Bioorganic chemistry (01-10-2020)“…[Display omitted] •Novel scaffold for antimicrobial peptides, containing muramic acid (Mur), was designed.•Glycopeptide library consisting of linear and cyclic…”
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Glycation of a lysine-containing tetrapeptide by d-glucose and d-fructose—influence of different reaction conditions on the formation of Amadori/Heyns products
Published in Carbohydrate research (22-09-2008)“…The site specificity, extent, and nature of modification of the tetrapeptide, Leu-Ser-Lys-Leu ( 1), incubated with d-glucose or d-fructose in methanol, or in…”
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The Maillard reaction induced modifications of endogenous opioid peptide enkephalin
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2013)“…Nonenzymatic glycation (Maillard reaction) is a posttranslational modification of peptides and proteins by sugars, which, after a cascade of reactions, leads…”
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Bicyclic Peptide Based Lectinomimic
Published in Croatica Chemica Acta (2017)“…Peptide based lectin mimetics represent an attractive approach for the development of artificial carbohydrate receptors that might find application in…”
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Synthesis of anthrose lipidic derivative as mimic of B. anthracis BclA glycoprotein for use in ELISA-like binding assays
Published in Journal of carbohydrate chemistry (12-02-2016)“…The surfaces of Bacillus anthracis endospores expose anthrose-containing oligosaccharides, which have been considered for use as a target for specific…”
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Peptide and amino acid glycation: new insights into the Maillard reaction
Published in Journal of peptide science (01-03-2004)“…Nonenzymatic glycation of proteins, peptides and other macromolecules (the Maillard reaction) has been implicated in a number of pathologies, most clearly in…”
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