Search Results - "Jakab, David"
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Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage
Published in Blood (10-05-2012)“…Type 2A VWD is characterized by the absence of large VWF multimers and decreased platelet-binding function. Historically, type 2A variants are subdivided into…”
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Characterization of the Pathogenicity of Novel Sequence Variants Identified in Type 1 VWD Subjects in the Zimmerman Program for the Molecular and Clinical Biology Study
Published in Blood (08-12-2017)“…Von Willebrand Disease (VWD) is the most prevalent inherited bleeding disorder. Von Willebrand factor's (VWF) complex intracellular processing may result in…”
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3
Bleeding Diathesis in Mice Lacking JAK2 in Platelets
Published in Blood (05-11-2020)“…The tyrosine kinase JAK2 is a critical component of intracellular JAK/STAT cytokine signaling cascades that is prevalent in hematopoietic cells such as…”
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Von Willebrand Factor Propeptide to Antigen Ratio Identifies Platelet Activation and Reduced VWF Survival Phenotype in Mice
Published in Journal of thrombosis and haemostasis (24-01-2018)Get full text
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Expression of Sequence Variants Identified in Type 1 VWD Subjects in the Zimmerman Program Study Reveals Defects in VWF Secretion and Multimerization
Published in Blood (02-12-2016)“…von Willebrand Disease (VWD) is the most prevalent inherited bleeding disorder. Type 1 is the most common form of VWD and results in a partial quantitative…”
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Upstream Mechanisms Causing Type 1C Von Willebrand Disease (VWD): Contribution Of Defective Von Willebrand Factor (VWF) Multimerization, Regulated Storage, and Secretion
Published in Blood (15-11-2013)“…One mechanism causing type 1 VWD is the reduced survival of VWF in plasma (type 1C VWD), characterized by markedly decreased VWF:Ag and VWF half-life,…”
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Bleeding diathesis in mice lacking JAK2 in platelets
Published in Blood advances (10-08-2021)“…The tyrosine kinase JAK2 is a critical component of intracellular JAK/STAT cytokine signaling cascades that is prevalent in hematopoietic cells, such as…”
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The Interplay of Unitary and Permutation Symmetries in Composite Quantum Systems
Published 01-01-2022“…We study three different topics linked together by an interplay of SU(d) and permutation symmetries. First, we study the spin-1 bilinear-biquadratic model on…”
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Dissertation -
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Extendibility of Brauer states
Published 07-11-2024“…We investigate the extendibility problem for Brauer states, focusing on the symmetric two-sided extendibility and the de Finetti extendibility. By employing…”
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Quantum phases of collective SU(3) spin systems with bipartite symmetry
Published 27-01-2020“…Phys. Rev. B 103, 214448 (2021) We study a bipartite collective spin-$1$ model with exchange interaction between the spins. The bipartite nature of the model…”
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Extendibility of Werner States
Published 29-08-2022“…We investigate the two-sided symmetric extendibility problem of Werner states. The interplay of the unitary symmetry of these states and the inherent bipartite…”
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The bilinear-biquadratic model on the complete graph
Published 25-09-2017“…J. Phys. A: Math. Theor. 51 105201 (2018) We study the spin-1 bilinear-biquadratic model on the complete graph of N sites, i.e., when each spin is interacting…”
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Journal Article