Search Results - "Jakóbisiak, Marek"

Proteasome Inhibition Potentiates Antitumor Effects of Photodynamic Therapy in Mice through Induction of Endoplasmic Reticulum Stress and Unfolded Protein Response by SZOKALSKA, Angelika, MAKOWSKI, Marcin, AGOSTINIS, Patrizia, VERFAILLIE, Tom, BUGAJSKI, Marek, GIETKA, Jan, ISSAT, Tadeusz, GLODKOWSKA, Eliza, MROWKA, Piotr, STOKLOSA, Tomasz, HAMBLIN, Michael R, MROZ, Pawel, NOWIS, Dominika, JAKOBISIAK, Marek, GOLAB, Jakub, WILCZYNSKI, Grzegorz M, KUJAWA, Marek, WOJCIK, Cezary, MLLYNARCZUK-BIALY, Izabela, SALWA, Pawel, BIL, Jacek, JANOWSKA, Sylwia

“…Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity toward tumor cells by inducing production of reactive oxygen…”
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Cardiotoxicity of the Anticancer Therapeutic Agent Bortezomib by Nowis, Dominika, Mączewski, Michał, Mackiewicz, Urszula, Kujawa, Marek, Ratajska, Anna, Wieckowski, Mariusz R, Wilczyński, Grzegorz M, Malinowska, Monika, Bil, Jacek, Salwa, Paweł, Bugajski, Marek, Wójcik, Cezary, Siński, Maciej, Abramczyk, Piotr, Winiarska, Magdalena, Dąbrowska-Iwanicka, Anna, Duszyński, Jerzy, Jakóbisiak, Marek, Golab, Jakub

“…Recent case reports provided alarming signals that treatment with bortezomib might be associated with cardiac events. In all reported cases, patients…”
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Effective Photoimmunotherapy of Murine Colon Carcinoma Induced by the Combination of Photodynamic Therapy and Dendritic Cells by JALILI, Ahmad, MAKOWSKI, Marcin, SIENKO, Jacek, SIERON, Aleksander, ADAMEK, Mariusz, BASAK, Grzegorz, MROZ, Pawet, KRASNODEBSKI, Ireneusz W, JAKOBISIAK, Marek, GOLAB, Jakub, SWITAJ, Tomasz, NOWIS, Dominika, WILCZYNSKI, Grzegorz M, WILCZEK, Ewa, CHORAZY-MASSALSKA, Magdalena, RADZIKOWSKA, Anna, MASLINSKI, Wlodzimierz, BIALY, Lukasz

“…Purpose: The unique mechanism of tumor destruction by photodynamic therapy (PDT), resulting from apoptotic and necrotic killing of tumor cells accompanied by…”
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Natural mechanisms protecting against cancer by Jakóbisiak, Marek, Lasek, Witold, Gołąb, Jakub

“…Carcinogenesis is a multistage process. At each step of this process, there are natural mechanisms protecting against development of cancer. The majority of…”
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The influence of photodynamic therapy on the immune response by Nowis, Dominika, Stokłosa, Tomasz, Legat, Magdalena, Issat, Tadeusz, Jakóbisiak, Marek, Gołąb, Jakub

“…Photodynamic therapy (PDT) is a clinically approved therapeutic modality used for the management of several types of tumors as well as non-malignant diseases…”
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Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor by Golab, Jakub, Nowis, Dominika, Skrzycki, Michal, Czeczot, Hanna, Baranczyk-Kuzma, Anna, Wilczynski, Grzegorz M, Makowski, Marcin, Mroz, Pawel, Kozar, Katarzyna, Kaminski, Rafal, Jalili, Ahmad, Kopec', Maciej, Grzela, Tomasz, Jakobisiak, Marek

“…Photodynamic therapy (PDT), a promising therapeutic modality for the management of solid tumors, is a two-phase treatment consisting of a photosensitizer and…”
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CpG Immunostimulatory Oligodeoxynucleotide 1826 Enhances Antitumor Effect of Interleukin 12 Gene-Modified Tumor Vaccine in a Melanoma Model in Mice by SWITAJ, Tomasz, JALILI, Ahmad, SASOR, Agata, SOCHA, Koryna, JAKOBISIAK, Marek, LASEK, Witold, JAKUBOWSKA, Anna B, DRELA, Nadzieja, STOKSIK, Magdalena, NOWIS, Dominika, BASAK, Grzegorz, GOLAB, Jakub, WYSOCKI, Piotr J, MACKIEWICZ, Andrzej

“…Purpose: The effectiveness of interleukin (IL)-12-secreting tumor vaccines in the treatment of mouse tumors could be enhanced by concurrent application of…”
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Inhibition of Cyclooxygenase-2 Indirectly Potentiates Antitumor Effects of Photodynamic Therapy in Mice by MAKOWSKI, Marcin, GRZELA, Tomasz, MROWKA, Piotr, WASIK, Maria, JAKOBISIAK, Marek, GOŁAB, Jakub, NIDERLA, Justyna, LAZARCZYK, Maciej, MROZ, Paweł, KOPEC, Maciej, LEGAT, Magdalena, STRUSINSKA, Katarzyna, KOZIAK, Katarzyna, NOWIS, Dominika

“…Purpose: The aim of the present study was to potentiate the antitumor effectiveness of photodynamic therapy (PDT). A cDNA microarray analysis was used to…”
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Interleukin 12-based Immunotherapy Improves the Antitumor Effectiveness of a Low-Dose 5-Aza-2′-Deoxycitidine Treatment in L1210 Leukemia and B16F10 Melanoma Models in Mice by KOZAR, Katarzyna, KAMINSKI, Rafal, SWITAJ, Tomasz, OŁDAK, Tomasz, MACHAJ, Eugeniusz, WYSOCKI, Piotr J, MACKIEWICZ, Andrzej, LASEK, Witold, JAKOBISIAK, Marek, GOŁAB, Jakub

“…Purpose : Recent findings indicating that many genes related to cancer development are silenced by an aberrant DNA methylation suggest that inhibitors of this…”
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Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo by ISSAT, Tadeusz, NOWIS, Dominika, BIL, Jacek, GIETKA, Jan, JAKOBISIAK, Marek, GOLAB, Jakub, LEGAT, Magdalena, MAKOWSKI, Marcin, KLEJMAN, Marcin P, URBANSKI, Jakub, SKIERSKI, Janusz, KORONKIEWICZ, Miroslawa, STOKLOSA, Tomasz, BRZEZINSKA, Agnieszka

“…The aim of the present study was to examine the potential antitumor activity of lovastatin and other statins together with pamidronate, a second generation…”
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Lovastatin Potentiates Antitumor Activity and Attenuates Cardiotoxicity of Doxorubicin in Three Tumor Models in Mice by Feleszko, W, Mlynarczuk, I, Balkowiec-Iskra, E Z, Czajka, A, Switaj, T, Stoklosa, T, Giermasz, A, Jakóbisiak, M

“…Lovastatin, a drug commonly used in the clinic to treat hypercholesterolemia, has previously been reported to exert antitumor effects in rodent tumor models…”
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Genetic Modification of T Cells Improves the Effectiveness of Adoptive Tumor Immunotherapy by Jakobisiak, Marek, Golab, Jakub

“…Appropriate combinations of immunotherapy and gene therapy promise to be more effective in the treatment of cancer patients than either of these therapeutic…”
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Interleukin 15 as a promising candidate for tumor immunotherapy by Jakobisiak, Marek, Golab, Jakub, Lasek, Witold

“…Abstract Interleukin 15 participates in the development of important immune antitumor mechanisms. It activates CD8+ T cells, natural killer (NK) cells, NK T…”
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Lovastatin potentiates antitumor activity of doxorubicin in murine melanoma via an apoptosis‐dependent mechanism by Feleszko, Wojciech, Młynarczuk, Izabela, Olszewska, Dominika, Jalili, Ahmad, Grzela, Tomasz, Lasek, Witold, Hoser, Grażyna, Korczak‐Kowalska, Grażyna, Jakóbisiak, Marek

“…Lovastatin, a drug successfully used in the clinic to prevent and to treat coronary heart disease, has recently been reported to decrease the incidence of…”
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Interleukin 12: still a promising candidate for tumor immunotherapy? by Lasek, Witold, Zagożdżon, Radosław, Jakobisiak, Marek

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Cerivastatin demonstrates enhanced antitumor activity against human breast cancer cell lines when used in combination with doxorubicin or cisplatin by Kozar, Katarzyna, Kaminski, Rafal, Legat, Magdalena, Kopec, Maciej, Nowis, Dominika, Skierski, Janusz S, Koronkiewicz, Miroslawa, Jakóbisiak, Marek, Golab, Jakub

“…Competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase are commonly used in the clinic to treat hypercholesterolemia and have been…”
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Erythropoietin Restores the Antitumor Effectiveness of Photodynamic Therapy in Mice with Chemotherapy- induced Anemia by GOŁAB, Jakub, OLSZEWSKA, Dominika, MROZ, Paweł, KOZAR, Katarzyna, KAMINSKI, Rafal, JALILI, Ahmad, JAKOBISIAK, Marek

“…Purpose: The study was designed to examine the impact ofanemia on the antitumor efficacy of photodynamic therapy (PDT) in a murine colon-26 adenocarcinoma…”
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Erythropoietin reduces cisplatin-induced neurotoxicity without impairment of cytotoxic effects against tumor cells by NOWIS, Dominika, LEGA, Magdalena, BIL, Jacek, KURZAJ, Zuzanna, ISSAT, Tadeusz, STOKLOSA, Tomasz, MIODUSZEWSKA, Barbara, KACZMAREK, Leszek, JAKOBISIAK, Marek, GOLAB, Jakub

“…Cisplatin, a widely used chemotherapeutic is approved for the management of various solid tumors. Administration of cisplatin is associated with induction of…”
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Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice by LASEK, Witold, BASAK, Grzegorz, JAKOBISIAK, Marek, SWITAJ, Tomasz, JAKUBOWSKA, Anna B, WYSOCKI, Piotr J, MACKIEWICZ, Andrzej, DRELA, Nadzieja, JALILI, Ahmad, KAMINSKI, Rafal, KOZAR, Katarzyna

“…In the present study, IL-12 gene-transduced B78-H1 melanoma cells (B78/IL-12) were used in combination with IL-15 to treat melanoma-bearing mice. Genetically…”
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Statins can modulate effectiveness of antitumor therapeutic modalities by Jakobisiak, Marek, Golab, Jakub

“…Despite significant, frequently very strong, antiproliferative and tumoricidal effects of statins demonstrated in vitro, their antitumor effects in animal…”
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