Search Results - "Jaisser, Frédéric"

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets by Barrera‐Chimal, Jonatan, Jaisser, Frédéric

“…Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the globe and is one of the main complications in patients with type 1 and…”
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Mineralocorticoid Receptor Activation and Mineralocorticoid Receptor Antagonist Treatment in Cardiac and Renal Diseases by Bauersachs, Johann, Jaisser, Frédéric, Toto, Robert

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Mineralocorticoid Receptor and Cardiovascular Disease by Buonafine, Mathieu, Bonnard, Benjamin, Jaisser, Frédéric

“…Abstract Activation of the mineralocorticoid receptor (MR) in the distal nephron by its ligand, aldosterone, plays an important role in sodium reabsorption and…”
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Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis by Daruich, Alejandra, Matet, Alexandre, Dirani, Ali, Bousquet, Elodie, Zhao, Min, Farman, Nicolette, Jaisser, Frédéric, Behar-Cohen, Francine

“…Central serous chorioretinopathy (CSCR) is a major cause of vision threat among middle-aged male individuals. Multimodal imaging led to the description of a…”
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MR (Mineralocorticoid Receptor) in Endothelial Cells: A Major Contributor in Pulmonary Arterial Hypertension Remodeling by Barrera-Chimal, Jonatan, Jaisser, Frédéric

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Immunosuppressive therapy after solid organ transplantation and the gut microbiota: Bidirectional interactions with clinical consequences by Gabarre, Paul, Loens, Christopher, Tamzali, Yanis, Barrou, Benoit, Jaisser, Frédéric, Tourret, Jérôme

“…Our understanding of the involvement of the gut microbiota (GM) in human health has expanded exponentially over the last few decades, particularly in the…”
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The myeloid mineralocorticoid receptor controls inflammatory and fibrotic responses after renal injury via macrophage interleukin-4 receptor signaling by Barrera-Chimal, Jonatan, Estrela, Gabriel R, Lechner, Sebastian M, Giraud, Sébastien, El Moghrabi, Soumaya, Kaaki, Shiem, Kolkhof, Peter, Hauet, Thierry, Jaisser, Frédéric

“…Acute kidney injury induced by ischemia/reperfusion is an independent risk factor for chronic kidney disease. Macrophage recruitment plays an essential role…”
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Mineralocorticoid receptor antagonists in kidney transplantation: time to consider? by Girerd, Sophie, Jaisser, Frédéric

“…Although patient survival is significantly improved by kidney transplantation (KT) in comparison with dialysis, it remains significantly lower than that…”
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Letter to the Editor From Behar-Cohen et al.: "The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy" by Behar-Cohen, Francine, Jaisser, Frédéric, Zhao, Min

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Emerging fields for therapeutic targeting of the aldosterone–mineralocorticoid receptor signaling pathway by Lother, Achim, Jaisser, Frédéric, Wenzel, Ulrich O.

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Myocardial fibrosis: biomedical research from bench to bedside by Gyöngyösi, Mariann, Winkler, Johannes, Ramos, Isbaal, Do, Quoc‐Tuan, Firat, Hüseyin, McDonald, Kenneth, González, Arantxa, Thum, Thomas, Díez, Javier, Jaisser, Frédéric, Pizard, Anne, Zannad, Faiez

“…Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial myocardial collagen network that occur in response to…”
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Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Protects Against Acute Kidney Injury–Mediated Chronic Kidney Disease: Role of Oxidative Stress by Lattenist, Lionel, Lechner, Sebastian M, Messaoudi, Smail, Le Mercier, Alan, El Moghrabi, Soumaya, Prince, Sonia, Bobadilla, Norma A, Kolkhof, Peter, Jaisser, Frédéric, Barrera-Chimal, Jonatan

“…Acute kidney injury induced by ischemia/reperfusion (IR) is a frequent complication in hospitalized patients. Mineralocorticoid receptor antagonism has shown…”
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Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway by Bonnard, Benjamin, Ibarrola, Jaime, Lima-Posada, Ixchel, Fernández-Celis, Amaya, Durand, Manon, Genty, Marie, Lopez-Andrés, Natalia, Jaisser, Frédéric

“…NGAL (neutrophil gelatinase-associated lipocalin; or lipocalin 2, Lcn2) is a novel mineralocorticoid target in the cardiovascular system. We showed that Lcn2…”
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Nanostructured Dense Collagen‐Polyester Composite Hydrogels as Amphiphilic Platforms for Drug Delivery by Wang, Xiaolin, Ronsin, Olivier, Gravez, Basile, Farman, Nicolette, Baumberger, Tristan, Jaisser, Frédéric, Coradin, Thibaud, Hélary, Christophe

“…Associating collagen with biodegradable hydrophobic polyesters constitutes a promising method for the design of medicated biomaterials. Current…”
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The mineralocorticoid receptor in chronic kidney disease by Barrera‐Chimal, Jonatan, Jaisser, Frédéric, Anders, Hans‐Joachim

“…Chronic kidney disease (CKD) is a major public health concern, affecting approximately 10% of the population worldwide. CKD of glomerular or tubular origin…”
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Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness by Galmiche, Guillaume, Pizard, Anne, Gueret, Alexandre, El Moghrabi, Soumaya, Ouvrard-Pascaud, Antoine, Berger, Stefan, Challande, Pascal, Jaffe, Iris Z., Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric

“…Arterial stiffness is recognized as a risk factor for many cardiovascular diseases. Aldosterone via its binding to and activation of the mineralocorticoid…”
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Aldosterone Target NGAL (Neutrophil Gelatinase–Associated Lipocalin) Is Involved in Cardiac Remodeling After Myocardial Infarction Through NFκB Pathway by Martínez-Martínez, Ernesto, Buonafine, Mathieu, Boukhalfa, Ines, Ibarrola, Jaime, Fernández-Celis, Amaya, Kolkhof, Peter, Rossignol, Patrick, Girerd, Nicolas, Mulder, Paul, López-Andrés, Natalia, Ouvrard-Pascaud, Antoine, Jaisser, Frédéric

“…Myocardial infarction (MI) is accompanied by cardiac fibrosis, which contributes to cardiac dysfunction. Mineralocorticoid receptor (MR) antagonists have…”
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Multifocal (tarsus and knee) activation of neuroarthropathy following rapid glycaemic correction by Dardari, Dured, Penfornis, Alfred, Amadou, Coralie, Phan, Franck, Bourron, Olivier, Davaine, Jean Michel, Foufelle, Fabienne, Jaisser, Frédéric, Laborne, Francois-Xavier, Hartemann, Agnes

“…To report a case of neuroarthropathy in the tarsus and knee following rapid glycaemic normalisation in a female patient with type I diabetes. A retrospective…”
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Chronic Systemic Dexamethasone Regulates the Mineralocorticoid/Glucocorticoid Pathways Balance in Rat Ocular Tissues by Zola, Marta, Mejlachowicz, Dan, Gregorio, Raquel, Naud, Marie-Christine, Jaisser, Frédéric, Zhao, Min, Behar-Cohen, Francine

“…Central serous chorioretinopathy (CSCR) is a retinal disease affecting the retinal pigment epithelium (RPE) and the choroid. This is a recognized side-effect…”
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NGAL is a Novel Target in Hypertension by Modulating the NCC-Mediated Renal Na Balance by Bonnard, Benjamin, El Moghrabi, Soumaya, Ueda, Kohei, Lattenist, Lionel, Soulie, Matthieu, López-Andrés, Natalia, Xhaard, Constance, Shimosawa, Tatsuo, Rossignol, Patrick, Jaisser, Frédéric

“…The expression of NGAL/lcn2 (neutrophil gelatinase-associated lipocalin) is directly modulated by mineralocorticoid receptor activation but its role in blood…”
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