Search Results - "Jain, Raksha"

Increasing awareness of sex differences in airway diseases by Raghavan, Deepa, Jain, Raksha

“…There is growing epidemiologic data demonstrating sex differences with respect to prevalence and progression of airway diseases, including asthma, chronic…”
Get full text

Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele by Middleton, Peter G, Mall, Marcus A, Dřevínek, Pavel, Lands, Larry C, McKone, Edward F, Polineni, Deepika, Ramsey, Bonnie W, Taylor-Cousar, Jennifer L, Tullis, Elizabeth, Vermeulen, François, Marigowda, Gautham, McKee, Charlotte M, Moskowitz, Samuel M, Nair, Nitin, Savage, Jessica, Simard, Christopher, Tian, Simon, Waltz, David, Xuan, Fengjuan, Rowe, Steven M, Jain, Raksha

“…Triple treatment with elexacaftor, tezacaftor, and ivacaftor in patients with cystic fibrosis who had one Phe508del allele and a minimal-function mutation…”
Get full text

Macro-financial nexus: a systematic review on the impact of macroeconomic factors on bank stock returns by Joseph, Aleena, E, Geetha, Radhakrishnan, Rohith, Jain, Raksha

“…AbstractThe performance of bank stocks exhibits a country’s overall financial health and signals economic growth. Therefore, understanding the interaction of…”
Get full text

Endothelin-1 Induces Alveolar Epithelial–Mesenchymal Transition through Endothelin Type A Receptor–Mediated Production of TGF-β1 by Jain, Raksha, Shaul, Philip W., Borok, Zea, Willis, Brigham C.

“…Endothelin-1 (ET-1) is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF), but the cellular mechanisms underlying the role it plays in this…”
Get full text

Temporal relationship between primary and motile ciliogenesis in airway epithelial cells by Jain, Raksha, Pan, Jiehong, Driscoll, James A, Wisner, Jeffrey W, Huang, Tao, Gunsten, Sean P, You, Yingjian, Brody, Steven L

“…Cilia are traditionally classified as motile or primary. Motile cilia are restricted to specific populations of well-differentiated epithelial cells, including…”
Get full text

Management of pregnancy in cystic fibrosis by Montemayor, Kristina, Tullis, Elizabeth, Jain, Raksha, Taylor-Cousar, Jennifer L

“…With recent therapeutic advances in care, people with cystic fibrosis (CF) are living longer and healthier lives. Development of the cystic fibrosis…”
Get full text

Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target by Mall, Marcus A, Davies, Jane C, Donaldson, Scott H, Jain, Raksha, Chalmers, James D, Shteinberg, Michal

“…Chronic airway inflammation is a central feature in the pathogenesis of bronchiectasis (BE), which can be caused by cystic fibrosis (CFBE; hereafter referred…”
Get full text

Lung transplantation and gender effects on survival of recipients with cystic fibrosis by Raghavan, Deepa, M.D, Gao, Ang, M.S, Ahn, Chul, Ph.D, Kaza, Vaidehi, M.D, Finklea, James, M.D, Torres, Fernando, M.D, Jain, Raksha, M.D., M.S.C.I

“…Purpose The overall life expectancy of Cystic Fibrosis (CF) women is shorter than CF men without accounting for lung transplant recipients. However, it is…”
Get full text

Prospectively evaluating maternal and fetal outcomes in the era of CFTR modulators: the MAYFLOWERS observational clinical trial study design by Jain, Raksha, Magaret, Amalia, Vu, Phuong T, VanDalfsen, Jill M, Keller, Ashley, Wilson, Alexandra, Putman, Melissa S, Mayer-Hamblett, Nicole, Esther Jr, Charles R, Taylor-Cousar, Jennifer L

“…IntroductionTherapeutic advances have markedly increased life expectancy for those with cystic fibrosis (CF), resulting in a median predicted survival over 50…”
Get full text

Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol by Kazmerski, Traci M, Stransky, Olivia M, Lee, MinJae, Prangley, Kelly A, Jain, Raksha, Georgiopoulos, Anna M, Shaw, Daniel S, Taylor-Cousar, Jennifer

“…IntroductionPeople with cystic fibrosis (CF) are living longer and healthier lives with a growing number considering and pursuing parenthood. The decision of…”
Get full text

Immunoreactive Trypsinogen in Infants Born to Women with Cystic Fibrosis Taking Elexacaftor-Tezacaftor-Ivacaftor by Patel, Payal, Yeley, Jana, Brown, Cynthia, Wesson, Melissa, Lesko, Barbara G, Slaven, James E, Chmiel, James F, Jain, Raksha, Sanders, Don B

“…Most people with cystic fibrosis (CF) are diagnosed following abnormal newborn screening (NBS), which begins with measurement of immunoreactive trypsinogen…”
Get full text

Chronic Pancreatitis Associated With a Variant of CFTR Gene Treated With Total Pancreatectomy and Autologous Islet Cell Transplantation by Agarwal, Shubham, Lingvay, Ildiko, Mirfakhraee, Sasan, Jain, Raksha

“…Total pancreatectomy is performed for pain relief in chronic pancreatitis. Concomitant autologous islet cell transplantation can be performed to improve…”
Get full text

Azithromycin is associated with increased survival in lung transplant recipients with bronchiolitis obliterans syndrome by Jain, Raksha, MD, Hachem, Ramsey R., MD, Morrell, Matthew R., MD, Trulock, Elbert P., MD, Chakinala, Murali M., MD, Yusen, Roger D., MD, MPH, Huang, Howard J., MD, Mohanakumar, Thalachallour, BVSc, PhD, Patterson, G. Alexander, MD, Walter, Michael J., MD

“…Background Previous studies have suggested that azithromycin improves lung function in lung transplant recipients with bronchiolitis obliterans syndrome (BOS)…”
Get full text

Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial by Heubi, James E., MD, Schaeffer, David, MD, Ahrens, Richard C., MD, Sollo, Natalie, MD, Strausbaugh, Steven, MD, Graff, Gavin, MD, Jain, Raksha, MD, Witte, Stephan, PhD, Forssmann, Kristin, MD

“…Objective To evaluate the safety and efficacy of a novel microbial lipase (NM-BL) in a liquid formulation for the treatment of exocrine pancreatic…”
Get full text

Engaging Stakeholders in the Development of a Reproductive Goals Decision AID for Women with Cystic Fibrosis by Stransky, Olivia M., Pam, Molly, Ladores, Sigrid L., Birru Talabi, Mehret, Borrero, Sonya, Godfrey, Emily M., Roe, Andrea H., Sawicki, Gregory S., Zuckerwise, Lisa C., Mody, Sheila, Mentch, Laura, Deal, Ashley, O’Leary, Raelynn, Taylor-Cousar, Jennifer L., Jain, Raksha, Kazmerski, Traci M.

“…Objective: More people with cystic fibrosis (pwCF) are reaching adulthood and considering their reproductive futures. Unfortunately, many pwCF report gaps in…”
Get full text

Evaluating Outcomes Disparities in the Hispanic Cystic Fibrosis Population by Rho, Jason, MD, Ahn, Chul, PhD, Gao, Ang, MS, Keller, Ashley, MPH, Jain, Raksha, MD

Get full text

An innovative phase II trial to establish proof of efficacy and optimal dose of a new inhaled epithelial sodium channel inhibitor BI 1265162 in adults and adolescents with cystic fibrosis: BALANCE-CFTM 1 by Goss, Christopher H, Jain, Raksha, Seibold, Wolfgang, Picard, Anne-Caroline, Hsu, Ming-Chi, Gupta, Abhya, Fajac, Isabelle

“…Inhibition of the epithelial sodium channel (ENaC) represents an important, mutation-agnostic therapeutic approach to restore airway surface liquid in patients…”
Get full text

Catamenial haemoptysis in females with cystic fibrosis: a case series with review of management strategies by Bozkanat, Kubra M., West, Natalie E., Ladores, Sigrid, Montemayor, Kristina, Tupayachi Ortiz, Maria Gabriela, Christianson, Mindy, Jain, Raksha

“…Catamenial haemoptysis, the expectoration of blood during menses, has not been extensively reported in the cystic fibrosis (CF) literature. We describe four…”
Get full text

Diagnosing Cystic Fibrosis in Adults: Better Late Than Never by Jain, Raksha

“…[...]in a recent analysis using the CFFPR, investigators reported 10- and 15-year survival rates of 76% and 65%, respectively, in adult-diagnosed patients, as…”
Get full text

Cystic Fibrosis: Highly Effective Targeted Therapeutics and the Impact on Sex and Racial Disparities by Montemayor, Kristina, Jain, Raksha

Get full text