Search Results - "Jain, Hemani"

Role of Cytogenetics and Fluorescence In Situ Hybridization in the Laboratory Workup of Acute Myeloid Leukemias by Jain, Hemani, Shetty, Dhanlaxmi

“…Abstract A new understanding of acute myeloid leukemia as a varied group of unique biologic entity has emerged, as a result of the identification of various…”
Get full text

Emergence of an unrelated highly aberrant clone in an AML patient at relapse four months after peripheral blood stem cell transplantation by Kadam, Pratibha S, Jain, Hemani V, Parikh, Purvish M, Saikia, Tapan K, Agarwal, Sandhya, Ambulkar, Indu

“…We report a case of AML-M1 with 5q aberration at diagnosis. The patient was treated with high-dose chemotherapy (HDCT). After remission induction, he received…”
Get full text

Treatment and follow-up of children with chronic myeloid leukaemia in chronic phase (CML-CP) in the tyrosine kinase inhibitor (TKI) era-Two decades of experience from the Tata Memorial Hospital paediatric CML (pCML) cohort by Roy Moulik, Nirmalya, Keerthivasagam, Swaminathan, Pandey, Ankita, Agiwale, Jayesh, Hegde, Kriti, Chatterjee, Gaurav, Dhamne, Chetan, Prasad, Maya, Chichra, Akanksha, Srinivasan, Shyam, Mohanty, Purvi, Jain, Hemani, Shetty, Dhanlaxmi, Tembhare, Prashant, Patkar, Nikhil, Narula, Gaurav, Subramanian, Papagudi G, Banavali, Shripad

“…Tyrosine kinase inhibitors (TKIs) have drastically improved the outcomes of pCML (paediatric CML) but data on long-term off-target toxicities of TKIs in…”
Get full text

To Study Outcomes in Young CML Treated with TKI. a Registry Data from Hematological Cancer Consortium (HCC) of India by Kapoor, Rajan, Sarkar, Laboni, Abraham, Aby, Rajendra, Akhil, Bhattacharyya, Jina, Mishra, Kundan, Korula, Anu, Biswajit, Dubashi, Nandini, Dr, Selvarajan, Sushil, Shetty, Alok, Nayak, Lingaraj, Karunakaran, Parathan, Das, Damodar, Kumar, Rajeev, Perumal Kalaiyarasi, Jayachandran, Kayal, Smita, Kumar, Gopa, Samal, Priyanka, Talukdar, Sewali Deka, Jain, Hemani, Palassery, Rasmi, Saldanha, Smitha Carol, Patkar, Nikhil, Kulkarni, Uday Prakash, Paul, Mobin, Mathews, Vikram

“…Background: Chronic Myeloid Leukemia (CML) is a hematological malignancy characterized by the abnormal proliferation of white blood cells. While CML is…”
Get full text

Cytogenetic profile and outcome of a pediatric acute promyelocytic leukemia patient presenting with isolated isochromosome 17q in absence of RARA rearrangement by Jain, Hemani, Shetty, Dhanlaxmi, Narula, Gaurav, Moulik, Nirmalya Roy, Tembhare, Prashant, Patkar, Nikhil, Subramanian, P.G., Banavali, Sripad

Get full text

Treating relapsed B cell-precursor ALL in children with a setting-adapted mitoxantrone-based intensive chemotherapy protocol (TMH rALL-18 PROTOCOL) — experience from Tata Memorial Hospital, India by Roy Moulik, Nirmalya, Keerthivasagam, Swaminathan, Velagala, Swetha V., Gollamudi, Venkata Rama Mohan, Agiwale, Jayesh, Dhamne, Chetan, Chichra, Akanksha, Srinivasan, Shyam, Shetty, Dhanlaxmi, Jain, Hemani, Subramanian, Papagudi G., Tembhare, Prashant, Chatterjee, Gaurav, Patkar, Nikhil, Narula, Gaurav, Banavali, Shripad

“…The outlook of relapsed ALL in low- and middle-income countries (LMICs) is dismal due to high treatment-related toxicities and inadequate resources. We report…”
Get full text

Evaluation of cytogenetic response in CML patients with variant Philadelphia translocation by Shetty, Dhanlaxmi, Talker, Elizabeth, Jain, Hemani, Talker, Judith, Patkar, Nikhil, Subramanian, Papagudi, Jain, Hasmukh, Bonda, Avinash, Punatar, Sachin, Gokarn, Anant, Bagal, Bhausaheb, Sengar, Manju, Khattry, Navin

“…Background and aim Molecular mechanism of translocation and outcome in variant chronic myeloid leukaemia (vCML) has been a topic of debate. While several…”
Get full text

A novel case of intrachromosomal amplification and insertion of RUNX1 on derivative chromosome 2 in pediatric AML by Jain, Hemani, Shetty, Dhanlaxmi, Roy Moulik, Nirmalya, Narula, Gaurav, Subramanian, P.G., Banavali, Sripad

“…Intrachromosomal amplification of RUNX1 gene on chromosome 21 (iAMP21) is a rare occurrence in acute myeloid leukemia (AML). Herein, we describe a case of AML…”
Get full text

2. Clinical, cytogenetic and genomic profiling of B-Other Acute Lymphoblastic Leukemia: An Indian cohort study by Shetty, Dhanlaxmi, Mohanty, Purvi, Jain, Hemani, Tembhare, Prashant, Patkar, Nikhil, Subramanian, Papagudi, Thorat, Jayashree, Nayak, Lingaraj, Gokarn, Anant, Punatar, Sachin, Jain, Hasmukh, Bagal, Bhausaheb, Srinivasan, Shyam, Chichra, Akanksha, Roy, Nirmalya, Dhamne, Chetan, Sengar, Manju, Khattry, Navin, Narula, Gaurav, Banavali, Shripad

Get full text

Importance of conventional cytogenetics in the identification of ins(19;X)(q13.1;p11.2q28) and t(1;11)(q10;p10), both, novel cytogenetic abnormalities in a pediatric AML case by Shetty, Dhanlaxmi, Mohanty, Purvi, Talker, Elizabeth, Jain, Hemani, Chaubal, Kruti, Tembhare, Prashant, Patkar, Nikhil, Subramanian, Papagudi, Moulik, Nirmalya Roy, Dhamne, Chetan, Narula, Gaurav, Banavali, Shripad

“…Acute Myeloid Leukemia (AML) is a heterogeneous disease with respect to morphology, immunophenotype, chromosomal abnormalities and genetic lesions. While a…”
Get full text

A rare case of hepatosplenic γδ T-cell lymphoma expressing CD19 with ring chromosome 7 and trisomy 8 by Jain, Hemani, Shetty, Dhanlaxmi, Jain, Hasmukh, Sengar, Manju, Khattry, Navin, Subramanian, P.G.

“…•Presenting CD19 positive HSTL with amplification of 7q forming ring chromosome 7 and trisomy 8.•This is a new finding in γδ HSTL and not yet reported in the…”
Get full text

Investigating the clinical, hematological and cytogenetic profile of endoreduplicated hypodiploids in BCP-ALL by Shetty, Dhanlaxmi, Amare, Pratibha Kadam, Mohanty, Purvi, Talker, Elizabeth, Chaubal, Kruti, Jain, Hemani, Tembhare, Prashant, Patkar, Nikhil, Chaturvedi, Anumeha, Subramanian, P.G., Moulik, Nirmalya, Dhamne, Chetan, Jain, Hasmukh, Bagal, Bhausaheb, Narula, Gaurav, Sengar, Manju, Khattry, Navin, Banavali, Shripad

“…Ploidy, besides known translocations in lymphoblasts, is a strong predictor of prognosis in B- cell progenitor acute lymphoblastic leukemia (BCP-ALL). While…”
Get full text

Role of cytogenetic abnormalities detected by fluorescence in situ hybridization as a prognostic marker: Pathogenesis & clinical course in patients with B-chronic lymphocytic leukaemia by Shetty, Dhanlaxmi, Jain, Hemani, Rohil, Yogita, Khattry, Navin, Sengar, Manju, Bagal, Bhausaheb, Jain, Hasmukh, Gokarn, Anant, Punatar, Sachin, Avinash Bonda, Venkata, Subramanian, P

“…Background & objectives: B-cell chronic lymphocytic leukaemia (B-CLL) is one of the most common forms of adult leukaemia, with a highly variable clinical…”
Get full text

Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol by Rajendra, Akhil, Jain, Hasmukh, Bonda, V. N. Avinash, Nayak, Lingaraj, Tembhare, Prashant, Shetty, Dhanlaxmi, Thorat, Jayashree, Jain, Hemani, Subramanian, Papagudi Ganesan, Patkar, Nikhil, Chatterjee, Gaurav, Khattry, Navin, Gokarn, Anant, Punatar, Sachin, Mokal, Smruti, Bagal, Bhausaheb, Sengar, Manju

“…The use of pediatrics-inspired protocols in adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) results in superior survival compared with the…”
Get full text

Observation on frequency & clinico-pathological significance of various cytogenetic risk groups in multiple myeloma: an experience from India by Kadam Amare, Pratibha S, Jain, Hemani, Nikalje, Shraddha, Sengar, Manju, Menon, Hari, Inamdar, Nitin, Subramanian, P G, Gujral, Sumeet, Shet, Tanuja, Epari, Sridhar, Nair, Reena

“…Multiple myeloma (MM) is a plasma cell malignancy characterized by cytogenetic heterogeneity. In comparison with conventional karyotyping, fluorescence in situ…”
Get full text

Long term clinical outcomes of adult hematolymphoid malignancies treated at Tata Memorial Hospital: An institutional audit by Khattry, Navin, Laskar, Siddhartha, Sengar, Manju, Rangarajan, Venkatesh, Shet, Tanuja, Subramanian, P, Epari, Sridhar, Bagal, Bhausaheb, Goda, Jayant, Agarwal, Archi, Jain, Hasmukh, Tembhare, Prashant, Patkar, Nikhil, Khanna, Nehal, Punatar, Sachin, Gokarn, Anant, Shetty, Dhanlakshmi, Jain, Hemani, Bonda, Avinash, Gota, Vikram, Hasan, Syed, Kode, Jyoti, Dutt, Shilpee, Kulkarni, Suyash, Shetty, Nitin, Sable, Nilesh, Deodhar, Jayita, Jadhav, Sunita, Pawaskar, Preeti, Mathew, libin, Menon, Hari, Nair, Reena, Kannan, Sadhana, Chiplunkar, Shubhadha, Gujral, Sumeet

“…Introduction: There is paucity of data from India about the outcomes of patients with various hematological malignancies. Since its formation in 2009, the…”
Get full text

Identification of various MLL gene aberrations that lead to MLL gene mutation in patients with acute lymphoblastic leukemia (ALL) and infants with acute leukemia by Pais, Anurita, Amare Kadam, Pratibha, Raje, Gauri, Sawant, Manisha, Kabre, Sharayu, Jain, Hemani, Advani, Suresh, Banavali, Shripad

“…Studies were done to investigate MLL gene aberrations using Conventional Cytogenetics, Southern blotting as well as FISH using a panel of probes on 218 cases…”
Get full text

Emergence of an unrelated highly aberrant clone in an AML patient at relapse four months after peripheral blood stem cell transplantation by Kadam, Pratibha S. Amare, Jain, Hemani V, Parikh, Purvish M, Saikia, Tapan K, Agarwal, Sandhya, Ambulkar, Indu

“…We report a case of AML-M1 with 5q aberration at diagnosis. The patient was treated with high-dose chemotherapy (HDCT). After remission induction, he received…”
Get full text

Cytogenetic profile and outcome of a pediatric acute promyelocytic leukemia patient presenting with isolated isochromosome 17q in absence of RARA rearrangement by Jain, Hemani, Shetty, Dhanlaxmi, Narula, Gaurav, Moulik, Nirmalya Roy, Tembhare, Prashant, Patkar, Nikhil, Subramanian, P G, Banavali, Sripad

Get full text

A rare case of hepatosplenic γδ T-cell lymphoma expressing CD19 with ring chromosome 7 and trisomy 8 by Jain, Hemani, Shetty, Dhanlaxmi, Jain, Hasmukh, Sengar, Manju, Khattry, Navin, Subramanian, P G

“…Hepatosplenic T-cell lymphoma (HSTL) is a rare subtype of peripheral T-cell lymphoma predominantly seen in young males. This disease presents with isolated…”
Get full text