Search Results - "Jain, Girish K."
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Differential effects of formononetin and cladrin on osteoblast function, peak bone mass achievement and bioavailability in rats
Published in The Journal of nutritional biochemistry (01-04-2011)“…Dietary soy isoflavones including genistein and daidzein have been shown to have favorable effects during estrogen deficiency in experimental animals and…”
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Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats
Published in Malaria journal (10-10-2011)“…Despite the wide spread use of lumefantrine, there is no study reporting the detailed preclinical pharmacokinetics of lumefantrine. For the development of…”
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3
Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor β-mediated osteogenic action of medicarpin
Published in The Journal of nutritional biochemistry (2012)“…Dietary isoflavones including genistein and daidzein have been shown to have favorable bone conserving effects during estrogen deficiency in experimental…”
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4
A standardized phytopreparation from an Indian medicinal plant (Dalbergia sissoo) has antiresorptive and bone-forming effects on a postmenopausal osteoporosis model of rat
Published in Menopause (New York, N.Y.) (01-12-2012)“…OBJECTIVEThe aim of this study was to evaluate the skeletal effects of an extract made from the leaves and pods of Dalbergia sissoo (butanol-soluble…”
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5
Total extract and standardized fraction from the stem bark of Butea monosperma have osteoprotective action: evidence for the nonestrogenic osteogenic effect of the standardized fraction
Published in Menopause (New York, N.Y.) (01-05-2010)“…OBJECTIVE:The aim of this study was to determine the skeletal effects of Butea total extract (BTE) and its acetone soluble fraction (ASF) from Butea…”
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Metabolic profiling of a novel antithrombotic compound, S002-333 and enantiomers: metabolic stability, species comparison and in vitro-in vivo extrapolation
Published in Biopharmaceutics & drug disposition (01-05-2016)“…Objective The aim of this research work was to characterize the metabolism of S002‐333, (2‐(4'‐methoxy‐benzenesulfonyl)‐2,3,4,9‐tetrahydro‐1H‐pyrido (3,4‐b)…”
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Pharmacokinetics, dose proportionality and permeability of S002-333 and its enantiomers, a potent antithrombotic agent, in rabbits
Published in Xenobiotica (02-11-2015)“…1. S002-333 [(2-(4′-methoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-pyrido (3,4-b) indole-3-carboxylic acid amide)] is a novel and potent antithrombotic active…”
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8
In vitro metabolism of a novel antithrombotic compound, S002-333, and its enantiomers: quantitative cytochrome P450 phenotyping, metabolic profiling and enzyme kinetic studies
Published in Xenobiotica (01-04-2014)“…Abstract 1. S002-333, (2-(4′-methoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-pyrido (3,4-b) indole-3-carboxylic acid amide) is a novel potent antithrombotic…”
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2,3-Dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercular agents: Design, synthesis, biological evaluation and SAR studies
Published in European journal of medicinal chemistry (01-06-2011)“…The alarming resurgence of tuberculosis (TB) underlines the urgent need for development of new and potent anti-TB drugs. Towards this goal we herein report the…”
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10
Extract and fraction from Ulmus wallichiana Planchon promote peak bone achievement and have a nonestrogenic osteoprotective effect
Published in Menopause (New York, N.Y.) (01-03-2010)“…OBJECTIVE:This study aimed to determine the skeletal effects of total ethanolic extract (TEE) and its butanolic fraction (BF) from the stem-bark of Ulmus…”
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Assessment of enhancement of peak bone gain by isoflavone enriched standardized soy extract in female rats
Published in Journal of functional foods (01-03-2014)“…•An isoflavone enriched soy extract (SE) increased modeling-directed bone gain in rats.•Ovariectomy (Ovx) and concurrent SE withdrawal preserved bone…”
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A novel flavonoid, 6-C-β-d-glucopyranosyl-(2S,3S)-(+)-3′,4′,5,7-tetrahydroxyflavanone, isolated from Ulmus wallichiana Planchon mitigates ovariectomy-induced osteoporosis in rats
Published in Menopause (New York, N.Y.) (01-05-2010)“…OBJECTIVE:The aim of this study was to determine the skeletal effect of 6-C-β-d-glucopyranosyl-(2S,3S)-(+)-3′,4′,5,7-tetrahydroxyflavanone (GTDF)/Ulmoside A, a…”
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13
Effect of centchroman coadministration on the pharmacokinetics of metformin in rats
Published in Indian journal of pharmacology (01-05-2010)“…Objectives : To study the effect of centchroman, a non-steroidal oral contraceptive, coadministration on the pharmacokinetics of metformin in rats. Materials…”
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14
Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor I super(2)-mediated osteogenic action of medicarpin
Published in The Journal of nutritional biochemistry (01-01-2012)“…Dietary isoflavones including genistein and daidzein have been shown to have favorable bone conserving effects during estrogen deficiency in experimental…”
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15
Transdermal controlled administration of verapamil — enhancement of skin permeability
Published in International journal of pharmaceutics (22-03-1996)“…Rapid permeation of verapamil hydrochloride (VHCI) across the skin using finite dose loading is documented. Transdermal drug delivery (TDD) systems of VHCI…”
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Dysobinin, a tetranortriterpenoid
Published in Acta crystallographica. Section C, Crystal structure communications (01-06-2000)“…The planar furan ring in the title compound (6β‐acetoxyazadirone, C30H38O6) is twisted with respect to the steroid D ring. The crystal structure is…”
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Modification and characterization of gellan gum
Published in Pharmaceutical Technology (01-07-2009)“…The authors modified gellan gum using microwave technology and a 3^sup 2^ randomized full-factorial design. The independent variables were the amount of…”
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