Search Results - "Jain, Gaurav K."
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A Comprehensive Study of Therapeutic Applications of Chamomile
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2022)“…Chamomile has a long history of traditional medicinal uses. The two commonly used varieties with therapeutic applications are German chamomile known as…”
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Liquid Crystalline Nanoparticles for Nasal Delivery of Rosuvastatin: Implications on Therapeutic Efficacy in Management of Epilepsy
Published in Pharmaceuticals (Basel, Switzerland) (30-10-2020)“…In the present study we investigated the protective role of intranasal rosuvastatin liquid crystalline nanoparticles (Ros-LCNPs) against pentylenetetrazole…”
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Design and Development of a Topical Nanogel Formulation Comprising of a Unani Medicinal Agent for the Management of Pain
Published in Gels (01-10-2023)“…The oil of the Unani medicinal herb Baboona (Matricaria chamomilla) has shown potential in the management of pain. However, predicaments such as poor skin…”
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Nano Matrix Soft Confectionary for Oral Supplementation of Vitamin D: Stability and Sensory Analysis
Published in Gels (19-04-2022)“…Vitamin D deficiency distresses nearly 50% of the population globally and multiple studies have highlighted the association of Vitamin D with a number of…”
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Design and development of letrozole nanoemulsion: A comparative evaluation of brain targeted nanoemulsion with free letrozole against status epilepticus and neurodegeneration in mice
Published in International journal of pharmaceutics (30-06-2019)“…[Display omitted] •Letrozole loaded nanoemulsion (LET-NE) was developed for selective brain targeting.•LET-NE increased the solubility and drug permeation in…”
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Enhanced antimalarial activity of lumefantrine nanopowder prepared by wet-milling DYNO MILL technique
Published in Colloids and surfaces, B, Biointerfaces (15-06-2012)“…[Display omitted] ► Nanopowder formulation of lumefantrine (as nanosuspension) was developed to increase antimalarial efficacy of lumefantrine. ► In the…”
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Formulation and development of tacrolimus-gellan gum nanoformulation for treatment of dry eye disease
Published in Colloids and surfaces, B, Biointerfaces (01-03-2022)“…The present study aimed at the development and evaluation of tacrolimus gellan gum nanoparticles (TGNPs) for the effective management of dry eye disease (DED)…”
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Therapeutic stratagems for vascular degenerative disorders of the posterior eye
Published in Drug discovery today (01-07-2012)“…► Therapeutic targets and drugs for vascular degenerative posterior eye disorders are reviewed. ► Novel carriers for targeted delivery their description and…”
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Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection
Published in Journal of advanced pharmaceutical technology and research (01-10-2019)“…The present study evaluated the antimicrobial activity of Azadirachta indica (AI), Cichorium intybus (CI), and Trigonella foenum-graecum (TFG) against…”
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Advancement of cell-penetrating peptides in combating triple-negative breast cancer
Published in Drug discovery today (01-11-2022)“…•Extensive research has been made in the search for an ideal anti-cancer therapy.•Cell penetrating peptides (CPPs) provides an efficient pathway for…”
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Transungual Delivery of Ketoconazole Nanoemulgel for the Effective Management of Onychomycosis
Published in AAPS PharmSciTech (01-12-2016)“…Ketoconazole (KCZ) nanoemulgel containing permeation enhancer was formulated as a vehicle for transungual drug delivery, and its efficacy to inhibit the growth…”
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Formulation development, optimization, and in vitro assessment of thermoresponsive ophthalmic pluronic F127-chitosan in situ tacrolimus gel
Published in Journal of biomaterials science. Polymer ed. (02-09-2021)“…To overcome problems associated with topical delivery of tacrolimus (TCS), a thermoresponsive in situ gel system containing pluronic F127 (PL), and chitosan…”
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Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote
Published in Nanomedicine (01-03-2009)“…Abstract The aim of the work was to develop, characterize, and carry out a clinical trial with nano–atropine sulfate (nano-AS) dry powder inhaler (DPI),…”
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Proglycosomes: A novel nano-vesicle for ocular delivery of tacrolimus
Published in Colloids and surfaces, B, Biointerfaces (01-09-2017)“…[Display omitted] •Novel vesicles composed of propylene glycol and phospholipid (PNVs) is proposed.•Propylene glycol modification improves vesicle…”
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Improved cardioprotective effects of hesperidin solid lipid nanoparticles prepared by supercritical antisolvent technology
Published in Colloids and surfaces, B, Biointerfaces (01-03-2020)“…[Display omitted] •Hesperidin solid lipid nanoparticles (HES-SLNs) were developed by supercritical antisolvent technique.•HES-SLNs improves aqueous solubility…”
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Nanostructured Therapeutic Systems of PUFAs for the Treatment of Glioblastoma Multiforme
Published in Current drug metabolism (01-12-2021)“…Glioblastoma multiforme (GBM) is a typical category of the most common and aggressive brain tumors, with a high incidence in older adults, particularly in…”
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Injectable in-situ gel depot system for targeted delivery of biologics to the retina
Published in Journal of drug targeting (2021)“…In current clinical settings, frequent intravitreal (IVT) injections of anti-vascular endothelial growth factors are used due to their short in-vivo half-life…”
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Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems
Published in Seminars in cancer biology (01-02-2021)“…Cancer, being the most prevalent and resistant disease afflicting any gender, age or social status, is the ultimate challenge for the scientific community. The…”
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Repurposing pharmaceutical excipients as an antiviral agent against SARS-CoV-2
Published in Journal of biomaterials science. Polymer ed. (2022)“…The limited time indorsed to face the COVID-19 emergency and large number of deaths across the globe, poses an unrelenting challenge to find apt therapeutic…”
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Revisiting the significance of nano vitamin D for food fortification and therapeutic application
Published in Drug development and industrial pharmacy (04-01-2024)“…Vitamin D (a prohormone) is an important micronutrient required by the body for skeletal homeostasis and a range of non-skeletal actions. Calcitriol, the…”
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