Search Results - "Jain, G K"

Assessment of Clinical Pharmacokinetic Drug-Drug Interaction of Antimalarial Drugs α/β-Arteether and Sulfadoxine-Pyrimethamine by Chhonker, Y S, Bhosale, V V, Sonkar, S K, Chandasana, H, Kumar, D, Vaish, S, Choudhary, S C, Bhadhuria, S, Sharma, S, Singh, R K, Jain, G K, Vaish, A K, Gaur, S P S, Bhatta, R S

“…Antimalarial drug combination therapy is now being widely used for the treatment of uncomplicated malaria. The objective of the present study was to…”
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Differential subcellular targeting of recombinant human α1-proteinase inhibitor influences yield, biological activity and in planta stability of the protein in transgenic tomato plants by Jha, Shweta, Agarwal, Saurabh, Sanyal, Indraneel, Jain, G.K, Amla, D.V

“…► Response of protein accumulation site on yield, stability, functionality and glycosylation by targeting to different subcellular locations. ► Maximum…”
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In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica by Shukla, A., Rasik, A.M., Jain, G.K., Shankar, R., Kulshrestha, D.K., Dhawan, B.N.

“…The activity of asiaticoside, isolated from Centella asiatica, has been studied in normal as well as delayed-type wound healing. In guinea pig punch wounds…”
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Bioanalytical method development and validation of natamycin in rabbit tears and its application to ocular pharmacokinetic studies by Bhatta, R.S., Chandasana, H., Rathi, C., Kumar, D., Chhonker, Y.S., Jain, G.K.

“…A new selective and sensitive high-performance liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) method was developed for the…”
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Nano-vectors for the Ocular Delivery of Nucleic Acid-based Therapeutics by Khar, R K, Jain, G K, Warsi, M H, Mallick, N, Akhter, S, Pathan, S A, Ahmad, F J

“…Nucleic acid-based therapeutics have gained a lot of interest for the treatment of diverse ophthalmic pathologies. The first to enter in clinic has been an…”
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Anilino-(2-bromophenyl) acetonitrile: a promising orally effective antileishmanial agent by Gupta, Suman, Tiwari, Suman, Bhaduri, A.P, Jain, G.K

“…Visceral leishmaniasis (VL) or kala-azar is a worldwide disseminated intracellular infection caused by the hemoflagellate protozoan parasites Leishmania…”
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Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis by Srivastava, K., Tyagi, A.M., Khan, K., Dixit, M., Lahiri, S., Kumar, A., Changkija, B., Khan, M.P., Nagar, G.K., Yadav, D.K., Maurya, R., Singh, S.P., Jain, G.K., Wahajuddin, Trivedi, R., Chattopadhyay, N., Singh, D.

“…Daidzein (Daid) has been implicated in bone health for its estrogen-‘like’ effects but low bioavailability, unfavorable metabolism and uterine estrogenicity…”
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A Simple and Rapid Evaluation of Methemoglobin Toxicity of 8-Aminoquinolines and Related Compounds by Srivastava, Pratima, Singh, S., Jain, G.K., Puri, S.K., Pandey, V.C.

“…Methemoglobin, a toxic ferric form of hemoglobin, is continuously formed in normal erythrocytes, but during abnormal situations in situ, the level is enhanced…”
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A time course study for the development of an immunocompromised wound model, using hydrocortisone by Gupta, A, Jain, G.K, Raghubir, R

“…Although wound healing is essentially a physiologic process, some chronic wounds exhibit considerable delay in healing. Often these do not heal perfectly in…”
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Simultaneous estimation of E- and Z-isomers of guggulsterone in rabbit plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study by Bhatta, R. S., Kumar, D., Chhonker, Y. S., Jain, G. K.

“…A sensitive and selective liquid chromatography/tandem mass spectrometric method was developed for simultaneous determination of E‐ and Z‐guggulsterone isomers…”
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Simultaneous estimation of 16α-hydroxycleroda-3,13(14) Z-dien-15,16-olide from Polyalthia longifolia and its metabolite in hamster plasma: application to pharmacokinetic study by Bhatta, R. S., Kumar, Devendra, Chhonker, Y. S., Kumar, Deepak, Singh, Suriya P., Sashidhara, Koneni V., Jain, G. K.

“…ABSTRACT A selective and sensitive LC–MS‐MS method was developed and validated for simultaneous estimation and pharmacokinetic studies of…”
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Bioanalytical method development and validation of novel antithrombotic agent S002-333 by LC-MS/MS and its application to pharmacokinetic studies by Bhatta, R. S., Kumar, D., Chhonker, Y. S., Saxena, A. K., Jain, G. K.

“…A rapid, sensitive and simple liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) method using an electrospray ionization (ECI) source for the…”
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Distribution of lovastatin to bone and its effect on bone turnover in rats by Jadhav, Satyawan B., Murthy, P. S. Narayana, Singh, M. M., Jain, G. K.

“…Statins, the widely used lipid‐lowering drugs, are inhibitors of 3‐hydroxy‐3‐methyl‐glutaryl coenzyme A (HMG‐CoA) reductase, which catalyses a rate‐limiting…”
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Wound healing in guinea pigs after topical application of starfish Pentaceraster regulus extract by Gupta, A., Lakshmi, V., Jain, G.K., Raghubir, R.

“…Objective: To investigate the healing efficacy of Pentaceraster regulus (starfish) aqueous-methanol extract on cutaneous wounds in guinea pigs. Method: Freshly…”
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Preliminary observations on the pharmacokinetics of CDRI compound 81/470 in calves by Nagaraja, N.V. (Central Drug Research Inst., Kucknow (India). Pharmamcokinetics and Metabolism Div.), Singh, S.K, Jain, G.K, Singh, S, Gupta, R.C

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Recent approaches for the treatment of periodontitis by Jain, Nilu, Jain, Gaurav K., Javed, Shamama, Iqbal, Zeenat, Talegaonkar, Sushama, Ahmad, Farhan J., Khar, Roop K.

“…Periodontal disease is a localised inflammatory response caused by the infection of a periodontal pocket arising from the accumulation of subgingival plaque…”
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In vitro percutaneous absorption of verapamil by Jain, G K, Agrawal, S S

“…The in vitro percutaneous absorption of verapamil hydrochloride (VHCl) was investigated in order to assess its feasibility for transdermal development. The…”
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Transdermal controlled administration of verapamil — enhancement of skin permeability by Jain, Girish K., Sharma, A.K., Agrawal, S.S.

“…Rapid permeation of verapamil hydrochloride (VHCI) across the skin using finite dose loading is documented. Transdermal drug delivery (TDD) systems of VHCI…”
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Contraceptive efficacy and hormonal profile of ferujol: a new coumarin from Ferula jaeschkeana by Singh, M M, Gupta, D N, Wadhwa, V, Jain, G K, Khanna, N M, Kamboj, V P

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In vitro transdermal delivery of atenolol using mouse and guinea pig by Jain, G K, Kaul, J L, Agrawal, S S

“…In vitro percutaneous absorption of atenolol was done in order to assess its feasibility for transdermal development across mouse and guinea pig skins using…”
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