Search Results - "Jain, Chesta"
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Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress
Published in JCI insight (22-07-2021)“…Cancer cells reprogram cellular metabolism to maintain adequate nutrient pools to sustain proliferation. Moreover, autophagy is a regulated mechanism to break…”
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2
PCBP1 is essential for proper iron absorption
Published in Blood (09-11-2023)Get full text
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Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload
Published in The Journal of clinical investigation (02-01-2019)“…Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis requires hepcidin, a liver-derived hormone that controls iron…”
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Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis
Published in Blood (21-04-2022)“…Intestinal iron absorption is activated during increased systemic demand for iron. The best-studied example is iron deficiency anemia, which increases…”
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Liraglutide Impacts Iron Homeostasis in a Murine Model of Hereditary Hemochromatosis
Published in Endocrinology (Philadelphia) (26-07-2024)“…Abstract Classic hereditary hemochromatosis (HH) is an autosomal recessive iron-overload disorder resulting from loss-of-function mutations of the HFE gene…”
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6
Myeloid Hif2α is not essential to maintain systemic iron homeostasis
Published in Experimental hematology (01-09-2023)“…•Myeloid deletion of Hif2α does not alter macrophage number or differentiation.•Hif2α in macrophages is not required for systemic or cellular iron…”
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Dietary Iron Is Necessary to Support Proliferative Regeneration after Intestinal Injury
Published in The Journal of nutrition (01-04-2024)“…Tissue repair and regeneration in the gastrointestinal system are crucial for maintaining homeostasis, with the process relying on intricate cellular…”
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8
Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload
Published in The Journal of clinical investigation (01-01-2019)“…Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis requires hepcidin, a liver-derived hormone that controls iron…”
Get full text
Journal Article -
9
Hepatic hepcidin/intestinal HIF-2 axis maintains iron absorption during iron deficiency and overload
Published in The Journal of clinical investigation (01-01-2019)“…Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis requires hepcidin, a liver-derived hormone that controls iron…”
Get full text
Journal Article -
10
Abstract C037: Characterization of cysteine dependency implicates glutathione metabolism as a critical adaptation axis in pancreatic cancer
Published in Cancer research (Chicago, Ill.) (15-09-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer that is highly malignant and lethal. The treatment options are limited, contributing to its high…”
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11
Performance analysis of integer wavelet transform for image compression
Published in 2011 3rd International Conference on Electronics Computer Technology (01-04-2011)“…For image compression, it is very necessary that the selection of transform should reduce the size of the resultant data as compared to the original data set…”
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