Search Results - "Jain, Aashish"
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Phylo-PFP: improved automated protein function prediction using phylogenetic distance of distantly related sequences
Published in Bioinformatics (01-03-2019)“…Abstract Motivation Function annotation of proteins is fundamental in contemporary biology across fields including genomics, molecular biology, biochemistry,…”
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Analyzing effect of quadruple multiple sequence alignments on deep learning based protein inter-residue distance prediction
Published in Scientific reports (07-04-2021)“…Protein 3D structure prediction has advanced significantly in recent years due to improving contact prediction accuracy. This improvement has been largely due…”
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The Balancing Act of Intrinsically Disordered Proteins: Enabling Functional Diversity while Minimizing Promiscuity
Published in Journal of molecular biology (05-04-2019)“…Intrinsically disordered proteins (IDPs) or regions (IDRs) perform diverse cellular functions, but are also prone to forming promiscuous and potentially…”
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Simulations of knotting of DNA during genome mapping
Published in Biomicrofluidics (01-03-2017)“…Genome mapping involves the confinement of long DNA molecules, in excess of 150 kilobase pairs, in nanochannels near the circa 50 nm persistence length of DNA…”
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A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes
Published in BMC biology (08-11-2022)“…Abstract Background The Nile rat ( Avicanthis niloticus ) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a…”
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ContactPFP: Protein Function Prediction Using Predicted Contact Information
Published in Frontiers in bioinformatics (01-06-2022)“…Computational function prediction is one of the most important problems in bioinformatics as elucidating the function of genes is a central task in molecular…”
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Brownian dynamics simulations of planar mixed flows of polymer solutions at finite concentrations
Published in Chemical engineering science (06-01-2015)“…Periodic boundary conditions for planar mixed flows are implemented in the context of a multi-chain Brownian dynamics simulation algorithm. The effect of shear…”
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Evaluation of the Kirkwood approximation for the diffusivity of channel-confined DNA chains in the de Gennes regime
Published in Biomicrofluidics (01-03-2015)“…We use Brownian dynamics with hydrodynamic interactions to calculate both the Kirkwood (short-time) diffusivity and the long-time diffusivity of DNA chains…”
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Cardiac surgery in a patient with implanted vagal nerve stimulator
Published in Annals of cardiac anaesthesia (01-01-2018)“…The prevalence of epilepsy worldwide is around 0.5%-2% of the population. Antiepileptic medications are the first line of treatment in most of the cases but…”
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Designing regression approach for mode frequency prediction of empty and filled steel silos
Published in Heliyon (01-12-2023)“…In this study the primary objective is to design prediction model for the free vibration analysis of thin circular cylindrical steel silos having various…”
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Clinical Use of a Real-World Low Carbohydrate Diet Resulting in Reduction of Insulin Dose, Hemoglobin A1c, and Weight
Published in Frontiers in nutrition (Lausanne) (11-08-2021)“…Type 2 Diabetes Mellitus (T2DM) is increasing in epidemic proportions. In addition to the morbidity and mortality, for those treated with insulin, the…”
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NNTox: Gene Ontology-Based Protein Toxicity Prediction Using Neural Network
Published in Scientific reports (29-11-2019)“…With advancements in synthetic biology, the cost and the time needed for designing and synthesizing customized gene products have been steadily decreasing…”
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Headache and seizures after cervical epidural injection in a patient undergoing coronary artery bypass grafting
Published in Annals of cardiac anaesthesia (01-07-2012)“…Epidural analgesia is widely used in cardiothoracic surgery. Most of the complications associated with epidural analgesia are related to the insertion…”
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Identification of Moonlighting Proteins in Genomes Using Text Mining Techniques
Published in Proteomics (Weinheim) (01-11-2018)“…Moonlighting proteins is an emerging concept for considering protein functions, which indicate proteins with two or more independent and distinct functions. An…”
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Protein contact map refinement for improving structure prediction using generative adversarial networks
Published in Bioinformatics (Oxford, England) (11-10-2021)“…Abstract Motivation Protein structure prediction remains as one of the most important problems in computational biology and biophysics. In the past few years,…”
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Prediction of protein group function by iterative classification on functional relevance network
Published in Bioinformatics (15-04-2019)“…Abstract Motivation Biological experiments including proteomics and transcriptomics approaches often reveal sets of proteins that are most likely to be…”
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Machine Learning Approaches Towards Protein Structure and Function Prediction
Published 01-01-2021“…Proteins are drivers of almost all biological processes in the cell. The functions of a protein are dependent on their three-dimensional structure and…”
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Dissertation -
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Low-cost non-intrusive device identification system
Published in 2016 IEEE Dallas Circuits and Systems Conference (DCAS) (01-10-2016)“…This paper explains the design and implementation of a low cost Non-Intrusive Load Monitoring (NILM) system. The system is designed using open source hardware…”
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Conference Proceeding -
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Transcaval aortic valve implantation in a patient with Larsen syndrome: technical and anesthetic challenges
Published in Indian journal of thoracic and cardiovascular surgery (01-07-2021)“…Transcatheter aortic valve implantation has emerged as a therapeutic option for patients with symptomatic severe aortic stenosis who are inoperable, or at very…”
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Journal Article