Search Results - "Jahjah, Tiya"
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miR-155 regulates physiological angiogenesis but an miR-155-rich microenvironment disrupts the process by promoting unproductive endothelial sprouting
Published in Cellular and molecular life sciences : CMLS (01-04-2022)“…Angiogenesis involves cell specification orchestrated by regulatory interactions between the vascular endothelial growth factor and Notch signaling pathways…”
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Angiogenesis Invasion Assay to Study Endothelial Cell Invasion and Sprouting Behavior
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Angiogenesis is the formation of new blood vessels from the existing vasculature. It is a fundamental process in developmental biology but also a pathological…”
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Tolerating DNA damage by repriming: Gap filling in the spotlight
Published in DNA repair (01-10-2024)“…Timely and accurate DNA replication is critical for safeguarding genome integrity and ensuring cell viability. Yet, this process is challenged by DNA damage…”
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Fibrillin-1 regulates endothelial sprouting during angiogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (06-06-2023)“…Fibrillin-1 is an extracellular matrix protein that assembles into microfibrils which provide critical functions in large blood vessels and other tissues…”
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Polymerase iota plays a key role during translesion synthesis of UV‐induced lesions in the absence of polymerase eta
Published in Photochemistry and photobiology (01-01-2024)“…Xeroderma pigmentosum (XP) variant cells are deficient in the translesion synthesis (TLS) DNA polymerase Polη (eta). This protein contributes to DNA damage…”
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Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
Published in Science advances (14-04-2023)“…Recent studies have described a DNA damage tolerance pathway choice that involves a competition between PrimPol-mediated repriming and fork reversal. Screening…”
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