Search Results - "Jahan, Cyprien"
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Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2020)“…Primary human hepatocytes (PHHs) are an essential tool for modeling drug metabolism and liver disease. However, variable plating efficiencies, short lifespan…”
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A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations
Published in Cell host & microbe (12-08-2020)“…Although there is no effective cure for chronic hepatitis B virus (HBV) infection, antibodies are protective and correlate with recovery from infection. To…”
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POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing
Published in Science advances (03-11-2023)“…Unintegrated retroviral DNA is transcriptionally silenced by host chromatin silencing factors. Here, we used the proteomics of isolated chromatin segments…”
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SAT-188-Expansion and genetic modification of primary hepatocytes to study long-term hepatitis B virus infection
Published in Journal of hepatology (01-04-2019)Get full text
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A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations
Published in Cell host & microbe (05-06-2020)“…Although there is no effective cure for chronic hepatitis B virus (HBV) infection, antibodies are protective and correlate with recovery from infection. To…”
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Journal Article -
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An RNA-based system to study hepatitis B virus replication and evaluate antivirals
Published in Science advances (14-04-2023)“…Hepatitis B virus (HBV) chronically infects an estimated 300 million people, and standard treatments are rarely curative. Infection increases the risk of liver…”
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