Search Results - "Jagu, Elodie"
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Site-Selective and Rewritable Labeling of DNA through Enzymatic, Reversible, and Click Chemistries
Published in ACS central science (22-04-2020)“…Current methods for bioconjugation rely on the introduction of stable linkers that lack the required versatility to perform sequential functionalizations…”
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FRET-Based Method for Direct, Real-Time Measurement of DNA Methyltransferase Activity
Published in Bioconjugate chemistry (20-01-2021)“…DNA methyltransferase activity is associated with a host of diseases, including cancers, where global hypomethylation of the genome, as well as marked changes…”
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3
Polyamine-based analogs and conjugates as antikinetoplastid agents
Published in European journal of medicinal chemistry (20-10-2017)“…Naturally occurring polyamines: putrescine, spermidine and spermine are crucial for Kinetoplastid growth and persistence. These aliphatic polycations are…”
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Spermine-NBD as fluorescent probe for studies of the polyamine transport system in Leishmania donovani
Published in Bioorganic & medicinal chemistry letters (15-07-2019)“…[Display omitted] This study describes the synthesis of fluorescent probes as potential substrates for the polyamine transport system (PTS) of Leishmania…”
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Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives
Published in European journal of medicinal chemistry (25-04-2018)“…This study describes the synthesis and the biological evaluation of twenty-four original bis(benzyl)spermidines. Structural modifications of the polyamine…”
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Synthesis and in vitro antikinetoplastid activity of polyamine–hydroxybenzotriazole conjugates
Published in Bioorganic & medicinal chemistry (01-01-2017)“…[Display omitted] Thirteen new polyamine derivatives coupled to hydroxybenzotriazole have been synthesized and evaluated for their in vitro antikinetoplastid…”
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Design, synthesis and in vitro antikinetoplastid evaluation of N-acylated putrescine, spermidine and spermine derivatives
Published in Bioorganic & medicinal chemistry letters (15-01-2015)“…A structure-activity relationship study on polyamine derivatives led to the synthesis and the determination of antikinetoplastid activity of 17 compounds…”
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