Search Results - "Jagst, Michelle"
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Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment
Published in JHEP reports (01-03-2024)“…In the absence of a hepatitis E virus (HEV)-specific antiviral treatment, sofosbuvir has recently been shown to have antiviral activity against HEV in vivo…”
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Performance of sofosbuvir and NITD008 in extrahepatic neuronal cells against HEV
Published in Antiviral research (01-07-2024)“…Hepatitis E is an underestimated disease, leading to estimated 20 million infections and up to 70,000 deaths annually. Infections are mostly asymptomatic, but…”
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Neuroinvasion and neurotropism of severe acute respiratory syndrome coronavirus 2 infection
Published in Current opinion in microbiology (01-06-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019, contributes to neurological pathologies in…”
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A LysR‐type transcriptional regulator controls the expression of numerous small RNAs in Agrobacterium tumefaciens
Published in Molecular microbiology (01-07-2021)“…Small RNAs (sRNAs) are universal posttranscriptional regulators of gene expression and hundreds of sRNAs are frequently found in each and every bacterium. In…”
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Modeling extrahepatic hepatitis E virus infection in induced human primary neurons
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2024)“…Hepatitis E virus (HEV) infections are one of the most common causes of acute viral hepatitis, annually causing over 3 million symptomatic cases and 70,000…”
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SAT-341 Discovery of a pan-genotypic hepatitis E virus replication inhibitor
Published in Journal of hepatology (01-06-2024)Get full text
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Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients
Published in Hepatology (Baltimore, Md.) (01-12-2023)“…Chronic HEV infections remain a serious problem in immunocompromised patients, as specifically approved antiviral drugs are unavailable. In 2020, a 24-week…”
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FRI-244 - Identification of resistance-associated variants after sofosbuvir treatment in chronic hepatitis E patients
Published in Journal of hepatology (01-06-2023)Get full text
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Identification of resistance-associated variants after sofosbuvir treatment in chronic hepatitis E patients
Published in Journal of hepatology (01-06-2023)Get full text
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Propionic acid promotes neurite recovery in damaged multiple sclerosis neurons
Published in Brain communications (2024)“…Neurodegeneration in the autoimmune disease multiple sclerosis still poses a major therapeutic challenge. Effective drugs that target the inflammation can only…”
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