Search Results - "Jagoe, Christopher T"

[1,3]-Sigmatropic rearrangement of allyl vinyl ethers at ambient temperature in 3.0 M lithium, perchlorate-diethyl ether by Grieco, Paul A, Clark, Jerry D, Jagoe, Christopher T

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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 1:  Synthetic Strategy and Preparation of a Common Precursor by Mickel, Stuart J, Sedelmeier, Gottfried H, Niederer, Daniel, Daeffler, Robert, Osmani, Adnan, Schreiner, Klaus, Seeger-Weibel, Manuela, Bérod, Brigitte, Schaer, Karl, Gamboni, Remo, Chen, Stephen, Chen, Weichun, Jagoe, Christopher T, Kinder, Frederick R, Loo, Mauricio, Prasad, Kapa, Repič, Oljan, Shieh, Wen-Chung, Wang, Run-Ming, Waykole, Liladhar, Xu, David D, Xue, Song

“…The synthetic strategy for producing multigram quantities of (+)-discodermolide (1) using a hybridized Novartis−Smith−Paterson synthetic route via common…”
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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 3:  Synthesis of Fragment C15 - 21 by Mickel, Stuart J, Sedelmeier, Gottfried H, Niederer, Daniel, Schuerch, Friedrich, Koch, Guido, Kuesters, E, Daeffler, Robert, Osmani, Adnan, Seeger-Weibel, Manuela, Schmid, E, Hirni, Alfred, Schaer, Karl, Gamboni, Remo, Bach, Andrew, Chen, Stephen, Chen, Weichun, Geng, Peng, Jagoe, Christopher T, Kinder, Frederick R, Lee, George T, McKenna, Joseph, Ramsey, Timothy M, Repič, Oljan, Rogers, Larry, Shieh, Wen-Chung, Wang, Run-Ming, Waykole, Liladhar

“…Smith's procedure of preparing fragment C15 - 21 (5) from common precursor 3 was optimized. The ease of plant operations made this six-step route successful…”
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Synthesis and Antitumor Activity of Ester-Modified Analogues of Bengamide B by Kinder, Frederick R, Versace, Richard W, Bair, Kenneth W, Bontempo, John M, Cesarz, David, Chen, Steven, Crews, Phillip, Czuchta, Ania M, Jagoe, Christopher T, Mou, Yin, Nemzek, Raphael, Phillips, Penny E, Tran, Long D, Wang, RunMing, Weltchek, Susan, Zabludoff, Sonya

“…Bengamide B, a novel sponge-derived marine natural product with broad spectrum antitumor activity, was not suitable for further preclinical development because…”
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Synthesis of (.+-.)cervinomycins A1 and A2 by Kelly, T. Ross, Jagoe, Christopher T, Li, Qun

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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 2:  Synthesis of Fragments C1 - 6 and C9-14 by Mickel, Stuart J, Sedelmeier, Gottfried H, Niederer, Daniel, Schuerch, Friedrich, Grimler, Dominique, Koch, Guido, Daeffler, Robert, Osmani, Adnan, Hirni, Alfred, Schaer, Karl, Gamboni, Remo, Bach, Andrew, Chaudhary, Apurva, Chen, Stephen, Chen, Weichun, Hu, Bin, Jagoe, Christopher T, Kim, Hong-Yong, Kinder, Frederick R, Liu, Yugang, Lu, Yansong, McKenna, Joseph, Prashad, Mahavir, Ramsey, Timothy M, Repič, Oljan, Rogers, Larry, Shieh, Wen-Chung, Wang, Run-Ming, Waykole, Liladhar

“…Kilogram-scale syntheses of fragments C1 - 6 (6) and C9 - 14 (4) of (+)-discodermolide from common precursor 3 are described. Improved procedures for each step…”
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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 3:  Synthesis of Fragment C 15 - 21 by Mickel, Stuart J., Sedelmeier, Gottfried H., Niederer, Daniel, Schuerch, Friedrich, Koch, Guido, Kuesters, E., Daeffler, Robert, Osmani, Adnan, Seeger-Weibel, Manuela, Schmid, E., Hirni, Alfred, Schaer, Karl, Gamboni, Remo, Bach, Andrew, Chen, Stephen, Chen, Weichun, Geng, Peng, Jagoe, Christopher T., Kinder, Frederick R., Lee, George T., McKenna, Joseph, Ramsey, Timothy M., Repič, Oljan, Rogers, Larry, Shieh, Wen-Chung, Wang, Run-Ming, Waykole, Liladhar

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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 2:  Synthesis of Fragments C 1 - 6 and C 9-14 by Mickel, Stuart J., Sedelmeier, Gottfried H., Niederer, Daniel, Schuerch, Friedrich, Grimler, Dominique, Koch, Guido, Daeffler, Robert, Osmani, Adnan, Hirni, Alfred, Schaer, Karl, Gamboni, Remo, Bach, Andrew, Chaudhary, Apurva, Chen, Stephen, Chen, Weichun, Hu, Bin, Jagoe, Christopher T., Kim, Hong-Yong, Kinder, Frederick R., Liu, Yugang, Lu, Yansong, McKenna, Joseph, Prashad, Mahavir, Ramsey, Timothy M., Repič, Oljan, Rogers, Larry, Shieh, Wen-Chung, Wang, Run-Ming, Waykole, Liladhar

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Covalent binding of catechols to src family SH2 domains by Jagoe, Christopher T., Kreifels, Scott E., Li, Jongming

“…Src family SH2 domains contain an uncoupled cysteine residue, that, when arylated with air oxidized catechols, inhibits the protein from binding to otherwise…”
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