One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

One-pot multicomponent domino synthesis of highly functionalized dibenzo[b,d]furans

[Display omitted] A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]fura...

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Bibliographic Details
Published in:Tetrahedron letters Vol. 123; p. 154547
Main Authors: Jaggavarapu, Satyanaraya Reddy, Bhukta, Swadhapriya, Chatterjee, Rana, Rao Anna, Venkateswara, Dandela, Rambabu
Format: Journal Article
Language:English
Published: Elsevier Ltd 23-06-2023
Subjects:
Base promoted
Dibenzofuran
Domino synthesis
Metal-free
Multi-component reaction
Base promoted
Metal-free
Domino synthesis
Dibenzofuran
Multi-component reaction
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Summary:[Display omitted] A simple and efficient base-promoted one-pot multicomponent synthesis of diversely functionalized dibenzo[b,d]furans has been achieved. Herein, organic base DBU smoothly promoted the domino reactions 3-coumaranone, trans-β-nitrostyrenes and malononitrile to produce dibenzo[b,d]furan derivatives in ethanol medium. Remarkably, the resulting products were obtained as pure precipitates in good to moderate yields which were separated by simple filtration from the reaction medium.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2023.154547