Search Results - "Jager, P. L."

Psychiatric co‐morbidity is associated with increased risk of surgery in Crohn's disease by Ananthakrishnan, A. N., Gainer, V. S., Perez, R. G., Cai, T., Cheng, S.‐C., Savova, G., Chen, P., Szolovits, P., Xia, Z., Jager, P. L., Shaw, S. Y., Churchill, S., Karlson, E. W., Kohane, I., Perlis, R. H., Plenge, R. M., Murphy, S. N., Liao, K. P.

“…Summary Background Psychiatric co‐morbidity, in particular major depression and anxiety, is common in patients with Crohn's disease (CD) and ulcerative colitis…”
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Genetic variation at CR1 increases risk of cerebral amyloid angiopathy by BIFFI, A, SHULMAN, J. M, MESCHIA, J. F, SLOWIK, A, DE JAGER, P. L, GREENBERG, S. M, SCHNEIDER, J. A, BENNETT, D. A, ROSAND, J, JAGIELLA, J. M, CORTELLINI, L, AYRES, A. M, SCHWAB, K, BROWN, D. L, SILLIMAN, S. L, SELIM, M, WORRALL, B. B

“…Accumulated evidence suggests that a variant within the CR1 gene (single nucleotide polymorphism rs6656401), known to increase risk for Alzheimer disease (AD),…”
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Integrating risk factors : HLA-DRB11501 and Epstein-Barr virus in multiple sclerosis by DE JAGER, P. L, SIMON, K. C, MUNGER, K. L, RIOUX, J. D, HAFLER, D. A, ASCHERIO, A

“…Individuals with high levels of antibodies to the Epstein-Barr virus nuclear antigen 1 (EBNA-1) have an increased risk of developing multiple sclerosis (MS),…”
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Combined vertebral fracture assessment and bone mineral density measurement: a new standard in the diagnosis of osteoporosis in academic populations by Jager, P. L., Jonkman, S., Koolhaas, W., Stiekema, A., Wolffenbuttel, B. H. R., Slart, R. H. J. A.

“…Summary Vertebral Fracture Analysis enables the detection of vertebral fractures in the same session as bone mineral density testing. Using this method in…”
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Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer’s disease by Roostaei, T, Nazeri, A, Felsky, D, De Jager, P L, Schneider, J A, Pollock, B G, Bennett, D A, Voineskos, A N

“…The lack of strong association between brain beta-amyloid deposition and cognitive impairment has been a challenge for the Alzheimer’s disease (AD) field…”
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Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis by Simon, Kelly Claire, Munger, K. L., Kraft, P., Hunter, D. J., De Jager, P. L., Ascherio, A.

“…Risk of multiple sclerosis (MS) decreases with increasing plasma levels of 25-hydroxyvitamin D [25(OH)D]. If this association reflected a protective effect of…”
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Low testosterone is associated with disability in men with multiple sclerosis by Bove, R, Musallam, A, Healy, BC, Raghavan, K, Glanz, BI, Bakshi, R, Weiner, H, De Jager, PL, Miller, KK, Chitnis, T

“…Background: Gonadal steroids may modulate disease course in multiple sclerosis (MS). Objective: To assess the prevalence and clinical associations of…”
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Elevated Peripheral Neutrophils and Matrix Metalloproteinase 9 as Biomarkers of Functional Outcome Following Subarachnoid Hemorrhage by Chou, S. H.-Y., Feske, S. K., Simmons, S. L., Konigsberg, R. G. J., Orzell, S. C., Marckmann, A., Bourget, G., Bauer, D. J., De Jager, P. L., Du, R., Arai, K., Lo, E. H., Ning, M. M.

“…There is growing evidence supporting the role of inflammation in early brain injury and cerebral vasospasm following subarachnoid hemorrhage (SAH). Matrix…”
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The SORL1 gene and convergent neural risk for Alzheimer’s disease across the human lifespan by Felsky, D, Szeszko, P, Yu, L, Honer, W G, De Jager, P L, Schneider, J A, Malhotra, A K, Lencz, T, Ikuta, T, Pipitone, J, Chakravarty, M M, Lobaugh, N J, Mulsant, B H, Pollock, B G, Kennedy, J L, Bennett, D A, Voineskos, A N

“…Prior to intervention trials in individuals genetically at-risk for late-onset Alzheimer’s disease, critical first steps are identifying where (neuroanatomic…”
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Multiple sclerosis susceptibility alleles in African Americans by Johnson, B A, Wang, J, Taylor, E M, Caillier, S J, Herbert, J, Khan, O A, Cross, A H, De Jager, P L, Gourraud, P-A F, Cree, B C A, Hauser, S L, Oksenberg, J R

“…Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by complex genetics and multifaceted gene–environment interactions. Compared to…”
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The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases by De Jager, P L, Franchimont, D, Waliszewska, A, Bitton, A, Cohen, A, Langelier, D, Belaiche, J, Vermeire, S, Farwell, L, Goris, A, Libioulle, C, Jani, N, Dassopoulos, T, Bromfield, G P, Dubois, B, Cho, J H, Brant, S R, Duerr, R H, Yang, H, Rotter, J I, Silverberg, M S, Steinhart, A H, Daly, M J, Podolsky, D K, Louis, E, Hafler, D A, Rioux, J D

“…The intestinal flora has long been thought to play a role either in initiating or in exacerbating the inflammatory bowel diseases (IBD). Host defenses, such as…”
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Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome by Kalincik, T, Guttmann, C R G, Krasensky, J, Vaneckova, M, Lelkova, P, Tyblova, M, Seidl, Z, De Jager, P L, Havrdova, E, Horakova, D

“…It has not yet been established whether genetic predictors of multiple sclerosis (MS) susceptibility also influence disease severity and accumulation of…”
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Radiolabeled Amino Acids: Basic Aspects and Clinical Applications in Oncology by Jager, Pieter L, Vaalburg, Willem, Pruim, Jan, de Vries, Elisabeth G.E, Langen, Karl-Josef, Piers, D. Albertus

“…As the applications of metabolic imaging are expanding, radiolabeled amino acids may gain increased clinical interest. This review first describes the basic…”
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Life expectancy in differentiated thyroid cancer: a novel approach to survival analysis by Links, T P, van Tol, K M, Jager, P L, Plukker, J Th M, Piers, D A, Boezen, H M, Dullaart, R P F, de Vries, E G E, Sluiter, W J

“…In differentiated thyroid carcinoma 10-year survival rates amount to 80–95%. Because age at diagnosis varies widely, these survival rates strongly depend on…”
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Apolipoprotein E and change in episodic memory in blacks and whites by Barnes, L L, Arvanitakis, Z, Yu, L, Kelly, J, De Jager, P L, Bennett, D A

“…Apolipoprotein E (APOE) ε4 is related to faster decline in episodic memory in Whites, but the relation is unknown in Blacks. The purpose of this study was to…”
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Limited additional value of positron emission tomography in staging oesophageal cancer by van Westreenen, H. L., Westerterp, M., Sloof, G. W., Groen, H., Bossuyt, P. M. M., Jager, P. L., Comans, E. F., van Dullemen, H. M., Fockens, P., Stoker, J., van der Jagt, E. J., van Lanschot, J. J. B., Plukker, J. T. M.

“…Background: The detection of distant metastases in patients with oesophageal cancer may be improved with [18F]fluorodeoxyglucose positron emission tomography…”
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Predictors of severe stenosis at invasive coronary angiography in patients with normal myocardial perfusion imaging by Yokota, S., Ottervanger, J. P., Mouden, M., de Boer, M. J., Jager, P. L., Timmer, J. R.

“…Purpose Normal myocardial perfusion imaging (MPI) is associated with excellent prognosis. However, in patients with persisting symptoms, it may be difficult to…”
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Development of a radioiodinated apoptosis–inducing ligand, rhTRAIL, and a radiolabelled agonist TRAIL receptor antibody for clinical imaging studies by Duiker, EW, Dijkers, ECF, Lambers Heerspink, H, de Jong, S, van der Zee, AGJ, Jager, PL, Kosterink, JGW, de Vries, EGE, Lub‐de Hooge, MN

“…BACKGROUND AND PURPOSE The TNF‐related apoptosis inducing ligand (TRAIL) induces apoptosis through activation of the death receptors, TRAIL‐R1 and TRAIL‐R2…”
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Impact of [18F]fluorodeoxyglucose positron emission tomography on surgical management of melanoma patients by Bastiaannet, E., Oyen, W. J. G., Meijer, S., Hoekstra, O. S., Wobbes, T., Jager, P. L., Hoekstra, H. J.

“…Background: Several studies have shown adequate sensitivity and specificity of [18F]fluorodeoxyglucose positron emission tomography (FDG‐PET) for the detection…”
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The value of FDG-PET in the detection, grading and response to therapy of soft tissue and bone sarcomas; a systematic review and meta-analysis by Bastiaannet, E, Groen, H, Jager, P.L, Cobben, D.C.P, van der Graaf, W.T.A, Vaalburg, W, Hoekstra, H.J

“…Background: Sarcomas represent a significant diagnostic and therapeutic challenge that requires techniques to provide better assessment of the disease than…”
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