Search Results - "Jager, MJ"

HLA expression in uveal melanoma: there is no rule without some exception by Jager, Martine J., Hurks, H.Monique, Levitskaya, Jelena, Kiessling, Rolf

“…A decrease in the expression of HLA antigens is considered a characteristic of tumor progression and is considered an important tumor-escape mechanism. In…”
Get full text

A Dutch guideline for the treatment of scoliosis in neuromuscular disorders by Mullender, Mg, Blom, Na, De Kleuver, M, Fock, Jm, Hitters, Wmgc, Horemans, Amc, Kalkman, Cj, Pruijs, Jeh, Timmer, Rr, Titarsolej, Pj, Van Haasteren, Nc, Jager, Mj Van Tol-de, Van Vught, Aj, Van Royen, Bj

“…Children with neuromuscular disorders with a progressive muscle weakness such as Duchenne Muscular Dystrophy and Spinal Muscular Atrophy frequently develop a…”
Get full text

Cytogenetic or molecular analysis for prognosis? by Jager, M.J.

“…Summary Prognostication in uveal melanoma can have several functions: to advice the patient, to council patients with regard to monitoring, and to stratify…”
Get full text

CT and MR Imaging in the Diagnosis of Scleritis by Diogo, M C, Jager, M J, Ferreira, T A

“…Scleritis is a rare, underdiagnosed vision-threatening condition that can occur isolated or in association with other orbital abnormalities. The etiology of…”
Get full text

The Small Fatal Choroidal Melanoma Study. A Survey by the European Ophthalmic Oncology Group by Jouhi, Susanna, Jager, Martine J., de Geus, Stefan J.R., Desjardins, Laurence, Eide, Nils Andreas, Grange, Jean-Daniel, Kiilgaard, Jens Folke, Seregard, Stefan, Midena, Edoardo, Parrozzani, Raffaele, Caujolle, Jean-Pierre, Rospond-Kubiak, Iwona, Kivelä, Tero T.

“…To determine the size at which choroidal melanomas can metastasize and to report the characteristics of small fatal choroidal melanomas (SFCM). Retrospective…”
Get full text

Patients presenting with metastases: stage IV uveal melanoma, an international study by Garg, Gaurav, Finger, Paul T, Kivelä, Tero T, Simpson, E Rand, Gallie, Brenda L, Saakyan, Svetlana, Amiryan, Anush G, Valskiy, Vladimir, Chin, Kimberly J, Semenova, Ekaterina, Seregard, Stefan, Filì, Maria, Wilson, Matthew, Haik, Barrett, Caminal, Josep Maria, Catala-Mora, Jaume, Gutiérrez, Cristina, Pelayes, David E, Folgar, Anibal Martin, Jager, Martine Johanna, Doğrusöz, Mehmet, Luyten, Gregorius P M, Singh, Arun D, Suzuki, Shigenobu

“…To analyse ocular and systemic findings of patients presenting with systemic metastasis. It is an international, multicentre, internet-enabled, registry-based…”
Get more information

Macrophages and the Eye by JAGER, MJ

“…The members of the antigen‐presenting cell family are known under many names, such as macrophages, Langerhans cells, dendritic cells and monocytes. They can be…”
Get full text

Cell lines of conjunctival tumours and their potential use in research by Jager, M.J., Cao, J.

“…Summary Conjunctival melanoma is a rare malignancy, which may give rise to metastases. An effective treatment of these metastases is as yet lacking…”
Get full text

Biocompatibility of a fish scale-derived artificial cornea: Cytotoxicity, cellular adhesion and phenotype, and in vivo immunogenicity by van Essen, T.H, van Zijl, L, Possemiers, T, Mulder, A.A, Zwart, S.J, Chou, C.-H, Lin, C.C, Lai, H.J, Luyten, G.P.M, Tassignon, M.J, Zakaria, N, El Ghalbzouri, A, Jager, M.J

“…Abstract Purpose To determine whether a fish scale-derived collagen matrix (FSCM) meets the basic criteria to serve as an artificial cornea, as determined with…”
Get full text

The Pediatric Choroidal and Ciliary Body Melanoma Study: A Survey by the European Ophthalmic Oncology Group by Al-Jamal, Rana'a T, Cassoux, Nathalie, Desjardins, Laurence, Damato, Bertil, Konstantinidis, Lazaros, Coupland, Sarah E, Heimann, Heinrich, Petrovic, Aleksandra, Zografos, Leonidas, Schalenbourg, Ann, Velazquez-Martin, Juan P, Krema, Hatem, Bogdali, Anna, Markiewicz, Anna, Romanowska-Dixon, Bozena, Metz, Claudia H D, Biewald, Eva, Bornfeld, Norbert, Kiratli, Hayyam, Bronkhorst, Inge H G, Jager, Martine J, Marinkovic, Marina, Fili, Maria, Seregard, Stefan, Frenkel, Shahar, Pe'er, Jacob, Salvi, Sachin M, Rennie, Ian G, Rospond-Kubiak, Iwona, Kociecki, Jaroslaw, Kiilgaard, Jens Folke, Heegaard, Steffen, Cohen, Victoria M L, Sagoo, Mandeep S, Amiryan, Anush, Saakyan, Svetlana, Eide, Nils, Krohn, Jørgen, Midena, Edoardo, Parrozzani, Raffaele, Grange, Jean-Daniel, Kilic, Emine, Blasi, Maria Antonietta, Saornil, Maria Antonia, Kivelä, Tero T

“…To collect comprehensive data on choroidal and ciliary body melanoma (CCBM) in children and to validate hypotheses regarding pediatric CCBM: children younger…”
Get full text

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS by ZUIDERVAART, W, VAN NIEUWPOORT, F, HAYWARD, N. K, GRUIS, N. A, STARK, M, DIJKMAN, R, PACKER, L, BORGSTEIN, A.-M, PAVEY, S, VAN DER VELDEN, P, OUT, C, JAGER, M. J

“…In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK)…”
Get full text

MEKi‐related retinopathy by Jager, M.J., Dijk, E.H.C., Herpen, C.M.L., Marinkovic, M., Luyten, G.P., Kapiteijn, E.H., Boon, C.J.

“…Summary Patients that are being treated for different types of malignancies may develop eye problems, which may be due to their treatment. We studied patients…”
Get full text

Mechanisms of local immunosuppression in cutaneous melanoma by POLAK, M. E, BORTHWICK, N. J, GABRIEL, F. G, JOHNSON, P, HIGGINS, B, HURREN, J, MCCORMICK, D, JAGER, M. J, CREEL, I. A

“…Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases develop successfully in otherwise immunocompetent patients. To investigate the…”
Get full text

Human choroidal nevi histopathology revisited by Madigan, M.c., Vader, M., Ton, H., Velden, P., Jager, M.J.

“…Purpose Choroidal nevi are relatively common lesions seen in normally asymptomatic eyes. They show low potential for progression to melanoma but may produce…”
Get full text

Selecting uveal melanoma for PRAME‐TCR T cell immunotherapy by Jager, M.J., Krijgsman, D., Luyten, G.P.M., Luk, S.J., Velden, P. Van, Heemskerk, M.H.M.

“…Purpose To determine which uveal melanoma may be candidates for PRAME‐directed immunotherapy using TCR‐modified autologous T cells. Methods Expression of PRAME…”
Get full text

Insulin-like growth factor-1 receptor in uveal melanoma: A predictor for metastatic disease and a potential therapeutic target by ALL-ERICSSON, Charlotta, GIRNITA, Leonard, SEREGARD, Stefan, BARTOLAZZI, Armando, JAGER, Martine J, LARSSON, Olle

“…To investigate the expression of the insulin-like growth factor-1 receptor (IGF-1R) with special focus on its role in cell growth in uveal melanoma. Paraffin…”
Get full text

Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes by Hallermalm, Kristian, Seki, Kazutake, De Geer, Anna, Motyka, Bruce, Bleackley, R Chris, Jager, Martine J, Froelich, Christopher J, Kiessling, Rolf, Levitsky, Victor, Levitskaya, Jelena

“…IFN-gamma, a pleiotropic immune regulator, is implicated in both tumor immune surveillance and selection of tumor variants resistant to immune control, i.e.,…”
Get full text

Use of xenografts for preclinical drug testing by DE LANGE, MJ, NéMATI, F, VERSLUIS, M, JAGER, MJ, LUYTEN, GPM, DECAUDIN, D, VAN DER VELDEN, PA

“…Uveal melanoma(UM) originates from melanocytes just like cutaneous melanoma (CM) and similar to CM, the MAPK pathway is involved in the development of UM…”
Get full text

Epigenetic regulation of the epithelial phenotype in uveal melanoma by VERSLUIS, M, DE LANGE, MJ, VAN PELT, S, LUYTEN, GPM, JAGER, MJ, VAN DER VELDEN, PA

“…Purpose The presence of epithelial cells is a bad prognostic factor in uveal melanoma (UM) and epithelial tumors are characterized by high expression of…”
Get full text

Shifting exudative age‐related macular degeneration patients to ranibizumab after insufficient response to bevacizumab by de Geus, Stefan J. R., Jager, Martine J., Luyten, Gré P. M., Dijkman, Greet

Get full text