Curative Resection for Metastatic Solid Pseudopapillary Neoplasm of Pancreas—a Case Series

Curative Resection for Metastatic Solid Pseudopapillary Neoplasm of Pancreas—a Case Series

Solid pseudopapillary neoplasm (SPN) is an unusual tumor of the pancreas. Unlike ductal adenocarcinoma, SPN is commoner in young women and is indolent with better prognosis. Fifteen percent of patients, however, develop metastases, often synchronous and involving the liver or peritoneum. Owing to th...

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Bibliographic Details
Published in:Indian journal of surgical oncology Vol. 15; no. Suppl 2; pp. 232 - 237
Main Authors: Jagannathan, Aparna M., Rymbai, Manbha L., Anand, Abhilasha, Paul, Anoop, Das, Borna, Kodiatte, Thomas Alex, Vyas, Frederick L., Raju, Ravish Sanghi, Joseph, Philip
Format: Journal Article
Language:English
Published: New Delhi Springer India 01-05-2024
Subjects:
Medicine
Medicine & Public Health
Oncology
Original Article
Surgery
Surgical Oncology
Liver metastases
Liver resection
Solid pseudopapillary neoplasm (SPN)
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Summary:Solid pseudopapillary neoplasm (SPN) is an unusual tumor of the pancreas. Unlike ductal adenocarcinoma, SPN is commoner in young women and is indolent with better prognosis. Fifteen percent of patients, however, develop metastases, often synchronous and involving the liver or peritoneum. Owing to the paucity of cases, management of the metastatic disease is not clearly defined. Retrospective review of case notes of patients treated between 2006 and 2019. There were 53 patients with SPN of which 4 had hepatic metastases—3 synchronous and 1 metachronous. Two patients underwent simultaneous distal pancreatectomy and splenectomy with liver resection (right posterior sectionectomy and metastasectomy). One required right hepatectomy with metastasectomy for metachronous liver metastases. The other underwent a staged operation—remnant tumor excision with metastasectomy followed by right hepatectomy after portal vein embolization. All four patients are recurrence free on median follow-up of 38.5 months. In view of the excellent prognosis, we recommend radical resection of both the primary lesion and metastases for SPN.
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ISSN:0975-7651
0976-6952
DOI:10.1007/s13193-022-01690-9