Search Results - "Jagadesan, Sankarasubramanian"
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Gut Microbiota and Metabolic Specificity in Ulcerative Colitis and Crohn's Disease
Published in Frontiers in medicine (27-11-2020)“…Inflammatory bowel disease (IBD) represents multifactorial chronic inflammatory conditions in the gastrointestinal tract and includes Crohn's disease (CD) and…”
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Metagenomic Analysis of Microbial Community Affiliated with Termitarium Reveals High Lignocellulolytic Potential
Published in Current microbiology (01-04-2021)“…Termitarium (nest of termites) is a rich source of microbial populations whose resources remain untapped to date. Using the metagenomic sequencing approach, we…”
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Exosomes derived from differentiated human ADMSC with the Schwann cell phenotype modulate peripheral nerve-related cellular functions
Published in Bioactive materials (01-08-2022)“…Peripheral nerve regeneration remains a significant clinical challenge due to the unsatisfactory functional recovery and public health burden. Exosomes,…”
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Novel RNA-Seq Signatures Post-Methamphetamine and Oxycodone Use in a Model of HIV-Associated Neurocognitive Disorders
Published in Viruses (01-09-2023)“…In the 21st century, the effects of HIV-associated neurocognitive disorders (HAND) have been significantly reduced in individuals due to the development of…”
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Evaluation of Five Mammalian Models for Human Disease Research Using Genomic and Bioinformatic Approaches
Published in Biomedicines (01-08-2023)“…The suitability of an animal model for use in studying human diseases relies heavily on the similarities between the two species at the genetic, epigenetic,…”
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Effects of Acute and Chronic Gabapentin Treatment on Cardiovascular Function of Rats
Published in Cells (Basel, Switzerland) (25-11-2023)“…Gabapentin (GBP), a GABA analogue, is primarily used as an anticonvulsant for the treatment of partial seizures and neuropathic pain. Whereas a majority of the…”
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Quantitative Proteomics Identifies Novel Nrf2-Mediated Adaptative Signaling Pathways in Skeletal Muscle Following Exercise Training
Published in Antioxidants (09-01-2023)“…Exercise training (ExT) improves skeletal muscle health via multiple adaptative pathways. Nrf2 is a principal antioxidant transcription factor responsible for…”
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Identification of YWHAH as a Novel Brain-Derived Extracellular Vesicle Marker Post Long-Term Midazolam Exposure during Early Development
Published in Cells (Basel, Switzerland) (01-03-2023)“…Recently, the long-term use of sedative agents in the neonatal intensive care unit (NICU) has raised concerns about neurodevelopmental outcomes in exposed…”
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Genome sequence analysis of the Indian strain Mannheimia haemolytica serotype A2 from ovine pneumonic pasteurellosis
Published in Annals of microbiology (13-12-2018)“…Mannheimia haemolytica is a leading causative agent of pasteurellosis in ruminants. Genome of M. haemolytica strains from different hosts has been sequenced…”
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A Holistic Systems Approach to Characterize the Impact of Pre- and Post-natal Oxycodone Exposure on Neurodevelopment and Behavior
Published in Frontiers in cell and developmental biology (07-01-2021)“…Increased risk of oxycodone (oxy) dependency during pregnancy has been associated with altered behaviors and cognitive deficits in exposed offspring. However,…”
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Genome Sequence of Lactobacillus fermentum Strain MTCC 8711, a Probiotic Bacterium Isolated from Yogurt
Published in Genome announcements (Washington, DC) (26-09-2013)“…Lactobacillus fermentum strain MTCC 8711 is a lactic acid bacterium isolated from yogurt. Here, we describe the draft genome sequence and annotation of this…”
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Draft Genome Sequence of the Intermediate Rough Vaccine Strain Brucella abortus S19Δper Mutant
Published in Genome announcements (Washington, DC) (12-11-2015)“…Here, we report the genome sequence of the intermediate rough vaccine strain mutant, Brucella abortus S19Δper. The length of the draft genome was 3,271,238 bp,…”
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Development and evaluation of a core genome multilocus sequence typing (cgMLST) scheme for Brucella spp
Published in Infection, genetics and evolution (01-01-2019)“…Brucellosis is a zoonotic disease caused by Brucella spp. Brucella spp. can be sub-typed by multilocus sequence typing (MLST) method, which targets a set of…”
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Neurobehavioral Characterization of Perinatal Oxycodone-Exposed Offspring in Early Adolescence
Published in Journal of neuroimmune pharmacology (14-06-2024)“…The opioid epidemic has received considerable attention, but the impact on perinatal opioid-exposed (POE) offspring remains underexplored. This study addresses…”
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Identification of potential antigens from non-classically secreted proteins and designing novel multitope peptide vaccine candidate against Brucella melitensis through reverse vaccinology and immunoinformatics approach
Published in Infection, genetics and evolution (01-11-2017)“…Brucella melitensis is an intracellular pathogen resides in the professional and non-professional phagocytes of the host, causing zoonotic disease brucellosis…”
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Abstract 4121: Unveiling discordant views of a novel drug's influence on cell motility from proteomics and immunofluorescence perspectives
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Introduction: Metastasis is a leading cause of death in patients with solid tumors. Our group has discovered KBU2046, a selective inhibitor of cell motility…”
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A genome-wide SNP-based phylogenetic analysis distinguishes different biovars of Brucella suis
Published in Infection, genetics and evolution (01-07-2016)“…Brucellosis is an important zoonotic disease caused by Brucella spp. Brucella suis is the etiological agent of porcine brucellosis. B. suis is the most…”
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Identification of genetic variants of Brucella spp. through genome-wide association studies
Published in Infection, genetics and evolution (01-12-2017)“…Brucellosis is an important zoonotic disease caused by Brucella spp. We present a phylogeny of 552 strains based on genome-wide single nucleotide polymorphisms…”
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Novel Vaccine Candidates against Brucella melitensis Identified through Reverse Vaccinology Approach
Published in Omics (Larchmont, N.Y.) (01-11-2015)“…Global health therapeutics is a rapidly emerging facet of postgenomics medicine. In this connection, Brucella melitensis is an intracellular bacterium that…”
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