Search Results - "Jaffe, Julie M."

Modification of Clinical Presentation of Prostate Tumors by a Novel Genetic Variant in CYP3A4 by Rebbeck, Timothy R., Jaffe, Julie M., Walker, Amy H., Wein, Alan J., Malkowicz, S. Bruce

“…Background: Pathways involved in androgen metabolism have been implicated in the etiology of prostate cancer. The goal of this study was to evaluate the effect…”
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Collection of Genomic DNA by Buccal Swabs for Polymerase Chain Reaction-Based Biomarker Assays by Walker, Amy H., Najarian, Derek, White, David L., Jaffe, Julie M., Kanetsky, Peter A., Rebbeck, Timothy R.

“…Studies in molecular and genetic epidemiology require a high-throughput, low cost, and reliable means of genomic DNA collection. Buccal (cheek) swabs have been…”
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Hypersplenism induced by splenic vein ligation by Garibaldi, Brian, King, Karen E., Jaffe, Julie M., Moliterno, Alison R.

“…Warm autoimmune hemolytic anemia (AIHA) is a rare clinical entity. It is usually caused by an IgG autoantibody directed against the red blood cell membrane…”
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Glutathione S-Transferase-μ (GSTM1) and -θ (GSTT1) Genotypes in the Etiology of Prostate Cancer by Rebbeck, T R, Walker, A H, Jaffe, J M, White, D L, Wein, A J, Malkowicz, S B

“…The glutathione S -transferases (GSTs) are involved in the metabolism of numerous potential prostate carcinogens. Common homozygous germ-line deletions exist…”
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Association of SRD5A2 genotype and pathological characteristics of prostate tumors by JAFFE, J. M, MALKOWICZ, S. B, WALKER, A. H, MACBRIDE, S, PESCHEL, R, TOMASZEWSKI, J, VAN ARSDALEN, K, WEIN, A. J, REBBECK, T. R

“…The enzyme product of SRD5A2, 5alpha-reductase type II, is responsible for converting testosterone to the more metabolically active dihydrotestosterone…”
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