Search Results - "Jaffe, D."

Meteorological anomalies lead to elevated O3 in the western U.S. in June 2015 by Jaffe, D. A., Zhang, L.

“…In winter through early summer of 2014–2015, temperatures in the western U.S. were substantially enhanced due to a persistent high‐pressure ridge and warm…”
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Panorama Public: A Public Repository for Quantitative Data Sets Processed in Skyline by Sharma, Vagisha, Eckels, Josh, Schilling, Birgit, Ludwig, Christina, Jaffe, Jacob D., MacCoss, Michael J., MacLean, Brendan

“…To address the growing need for a centralized, community resource of published results processed with Skyline, and to provide reviewers and readers immediate…”
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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate by Chakraborty, Abhishek A, Laukka, Tuomas, Myllykoski, Matti, Ringel, Alison E, Booker, Matthew A, Tolstorukov, Michael Y, Meng, Yuzhong Jeff, Meier, Samuel R, Jennings, Rebecca B, Creech, Amanda L, Herbert, Zachary T, McBrayer, Samuel K, Olenchock, Benjamin A, Jaffe, Jacob D, Haigis, Marcia C, Beroukhim, Rameen, Signoretti, Sabina, Koivunen, Peppi, Kaelin, Jr, William G

“…Oxygen sensing is central to metazoan biology and has implications for human disease. Mammalian cells express multiple oxygen-dependent enzymes called…”
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ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression by Abdel-Wahab, Omar, Adli, Mazhar, LaFave, Lindsay M., Gao, Jie, Hricik, Todd, Shih, Alan H., Pandey, Suveg, Patel, Jay P., Chung, Young Rock, Koche, Richard, Perna, Fabiana, Zhao, Xinyang, Taylor, Jordan E., Park, Christopher Y., Carroll, Martin, Melnick, Ari, Nimer, Stephen D., Jaffe, Jacob D., Aifantis, Iannis, Bernstein, Bradley E., Levine, Ross L.

“…Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome, myeloproliferative neoplasms, and acute myeloid leukemia, and are associated…”
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Integrated proteomic analysis of post-translational modifications by serial enrichment by Mertins, Philipp, Qiao, Jana W, Patel, Jinal, Udeshi, Namrata D, Clauser, Karl R, Mani, D R, Burgess, Michael W, Gillette, Michael A, Jaffe, Jacob D, Carr, Steven A

“…A mass spectrometry–based method using serial enrichments of different post-translational modifications (SEPTM) enables high-coverage proteomic analysis of…”
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A Curated Resource for Phosphosite-specific Signature Analysis[S] by Krug, Karsten, Mertins, Philipp, Zhang, Bin, Hornbeck, Peter, Raju, Rajesh, Ahmad, Rushdy, Szucs, Matthew, Mundt, Filip, Forestier, Dominique, Jane-Valbuena, Judit, Keshishian, Hasmik, Gillette, Michael A., Tamayo, Pablo, Mesirov, Jill P., Jaffe, Jacob D., Carr, StevenA, Mani, D.R.

“…Pathway analysis of PTM data sets is typically performed at a gene-centric level because of the lack of appropriately curated PTM signature databases. We have…”
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Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions by Xu, Jian, Shao, Zhen, Li, Dan, Xie, Huafeng, Kim, Woojin, Huang, Jialiang, Taylor, Jordan E., Pinello, Luca, Glass, Kimberly, Jaffe, Jacob D., Yuan, Guo-Cheng, Orkin, Stuart H.

“…Polycomb repressive complex 2 (PRC2) plays crucial roles in transcriptional regulation and stem cell development. However, the context-specific functions…”
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Release of mercury halides from KCl denuders in the presence of ozone by Lyman, S. N., Jaffe, D. A., Gustin, M. S.

“…KCl-coated denuders have become a standard method for measurement of gaseous oxidized mercury, but their performance has not been exhaustively evaluated,…”
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Self-reported burden of caregiver of adults with depression: a cross-sectional study in five Western European countries by Balkaran, B. L, Jaffe, D. H, Umuhire, D, Rive, B, Milz, R. U

“…Abstract Background Caregiving in depression imposes a complex health and economic burden. Moreover, there is a paucity of studies examining the impact of…”
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Oxidation of elemental Hg in anthropogenic and marine airmasses by Timonen, H, Ambrose, J. L, Jaffe, D. A

“…Mercury (Hg) is a neurotoxin that bioaccumulates in the food chain. Mercury is emitted to the atmosphere primarily in its elemental form, which has a long…”
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Deep, Quantitative Coverage of the Lysine Acetylome Using Novel Anti-acetyl-lysine Antibodies and an Optimized Proteomic Workflow[S] by Svinkina, Tanya, Gu, Hongbo, Silva, Jeffrey C., Mertins, Philipp, Qiao, Jana, Fereshetian, Shaunt, Jaffe, Jacob D., Kuhn, Eric, Udeshi, Namrata D., Carr, Steven A.

“…Introduction of antibodies specific for acetylated lysine has significantly improved the detection of endogenous acetylation sites by mass spectrometry. Here,…”
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Top-down constraints on atmospheric mercury emissions and implications for global biogeochemical cycling by Song, S, Selin, N. E, Soerensen, A. L, Angot, H, Artz, R, Brooks, S, Brunke, E.-G, Conley, G, Dommergue, A, Ebinghaus, R, Holsen, T. M, Jaffe, D. A, Kang, S, Kelley, P, Luke, W. T, Magand, O, Marumoto, K, Pfaffhuber, K. A, Ren, X, Sheu, G.-R, Slemr, F, Warneke, T, Weigelt, A, Weiss-Penzias, P, Wip, D. C, Zhang, Q

“…We perform global-scale inverse modeling to constrain present-day atmospheric mercury emissions and relevant physiochemical parameters in the GEOS-Chem…”
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M67 Blue Stragglers with High-resolution Infrared Spectroscopy by Brady, K. E., Sneden, C., Pilachowski, C. A., Afşar, Melike, Mace, G. N., Jaffe, D. T., Gosnell, N. M., Seifert, R.

“…Abstract We report on the first detailed infrared chemical analysis of five binary members (S277, S997, S975, S1031, and S1195) in the open cluster M67 (NGC…”
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High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program by Labbé, David P., Zadra, Giorgia, Yang, Meng, Reyes, Jaime M., Lin, Charles Y., Cacciatore, Stefano, Ebot, Ericka M., Creech, Amanda L., Giunchi, Francesca, Fiorentino, Michelangelo, Elfandy, Habiba, Syamala, Sudeepa, Karoly, Edward D., Alshalalfa, Mohammed, Erho, Nicholas, Ross, Ashley, Schaeffer, Edward M., Gibb, Ewan A., Takhar, Mandeep, Den, Robert B., Lehrer, Jonathan, Karnes, R. Jeffrey, Freedland, Stephen J., Davicioni, Elai, Spratt, Daniel E., Ellis, Leigh, Jaffe, Jacob D., DʼAmico, Anthony V., Kantoff, Philip W., Bradner, James E., Mucci, Lorelei A., Chavarro, Jorge E., Loda, Massimo, Brown, Myles

“…Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression…”
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First Search for Short-Baseline Neutrino Oscillations at HFIR with PROSPECT by Ashenfelter, J, Balantekin, A B, Baldenegro, C, Band, H R, Bass, C D, Bergeron, D E, Berish, D, Bignell, L J, Bowden, N S, Bricco, J, Brodsky, J P, Bryan, C D, Bykadorova Telles, A, Cherwinka, J J, Classen, T, Commeford, K, Conant, A J, Cox, A A, Davee, D, Dean, D, Deichert, G, Diwan, M V, Dolinski, M J, Erickson, A, Febbraro, M, Foust, B T, Gaison, J K, Galindo-Uribarri, A, Gilbert, C E, Gilje, K E, Glenn, A, Goddard, B W, Hackett, B T, Han, K, Hans, S, Hansell, A B, Heeger, K M, Heffron, B, Insler, J, Jaffe, D E, Ji, X, Jones, D C, Koehler, K, Kyzylova, O, Lane, C E, Langford, T J, LaRosa, J, Littlejohn, B R, Lopez, F, Lu, X, Martinez Caicedo, D A, Matta, J T, McKeown, R D, Mendenhall, M P, Miller, H J, Minock, J M, Mueller, P E, Mumm, H P, Napolitano, J, Neilson, R, Nikkel, J A, Norcini, D, Nour, S, Pushin, D A, Qian, X, Romero-Romero, E, Rosero, R, Sarenac, D, Seilhan, B S, Sharma, R, Surukuchi, P T, Trinh, C, Tyra, M A, Varner, R L, Viren, B, Wagner, J M, Wang, W, White, B, White, C, Wilhelmi, J, Wise, T, Yao, H, Yeh, M, Yen, Y-R, Zhang, A, Zhang, C, Zhang, X, Zhao, M

“…This Letter reports the first scientific results from the observation of antineutrinos emitted by fission products of ^{235}U at the High Flux Isotope Reactor…”
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense by Lassen, Kara G., Kuballa, Petric, Conway, Kara L., Patel, Khushbu K., Becker, Christine E., Peloquin, Joanna M., Villablanca, Eduardo J., Norman, Jason M., Liu, Ta-Chiang, Heath, Robert J., Becker, Morgan L., Fagbami, Lola, Horn, Heiko, Mercer, Johnathan, Yilmaz, Omer H., Jaffe, Jacob D., Shamji, Alykhan F., Bhan, Atul K., Carr, Steven A., Daly, Mark J., Virgin, Herbert W., Schreiber, Stuart L., Stappenbeck, Thaddeus S., Xavier, Ramnik J.

“…A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk for the development of Crohn…”
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Specter: linear deconvolution for targeted analysis of data-independent acquisition mass spectrometry proteomics by Peckner, Ryan, Myers, Samuel A, Jacome, Alvaro Sebastian Vaca, Egertson, Jarrett D, Abelin, Jennifer G, MacCoss, Michael J, Carr, Steven A, Jaffe, Jacob D

“…Data-independent-acquisition-based mass spectrometry enables highly reproducible proteome analysis, but results interpretation is challenging owing to the…”
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Increasing springtime ozone mixing ratios in the free troposphere over western North America by Cooper, O. R, Parrish, D. D, Stohl, A, Trainer, M, Nédélec, P, Thouret, V, Cammas, J. P, Oltmans, S. J, Johnson, B. J, Tarasick, D, Leblanc, T, McDermid, I. S, Jaffe, D, Gao, R, Stith, J, Ryerson, T, Aikin, K, Campos, T, Weinheimer, A, Avery, M. A

“…In the lowermost layer of the atmosphere—the troposphere—ozone is an important source of the hydroxyl radical, an oxidant that breaks down most pollutants and…”
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A summated rating scale for measuring city image by Gilboa, Shaked, Jaffe, Eugene D., Vianelli, Donata, Pastore, Alberto, Herstein, Ram

“…•A new scale was developed for measuring city image among residents and tourist populations.•The scale was validated using Exploratory and Confirmatory Factor…”
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Use of a global model to understand speciated atmospheric mercury observations at five high-elevation sites by Weiss-Penzias, P, Amos, H. M, Selin, N. E, Gustin, M. S, Jaffe, D. A, Obrist, D, Sheu, G.-R, Giang, A

“…Atmospheric mercury (Hg) measurements using the Tekran® analytical system from five high-elevation sites (1400–3200 m elevation), one in Asia and four in the…”
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