Search Results - "Jaffal, Sahar M"

TRP channels in COVID-19 disease: Potential targets for prevention and treatment by Jaffal, Sahar M., Abbas, Manal A.

“…Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins…”
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The role of adenosine receptor ligands on inflammatory pain: possible modulation of TRPV1 receptor function by Haddad, Mansour, Alsalem, Mohammad, Aldossary, Sara A., Kalbouneh, Heba, Jaffal, Sahar M., Alshawabkeh, Qusai, Al Hayek, Sa’ed, Abdelhai, Omar, Barakat, Noor A., El-Salem, Khalid

“…Chronic pain has a debilitating consequences on health and lifestyle. The currently available analgesics are often ineffective and accompanied by undesirable…”
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Antinociceptive Action of Moringa peregrina is Mediated by Interaction with α2-Adrenergic Receptor by Jaffal, Sahar M., Al-Najjar, Belal O., Abbas, Manal A., Oran, Sawsan A.

“…Moringa peregrina is an edible, drought resistant tree native to semiarid countries. It is used in folk medicine as painkiller. In this study, the…”
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Interaction of the synthetic cannabinoid WIN55212 with tramadol on nociceptive thresholds and core body temperature in a chemotherapy-induced peripheral neuropathy pain model by Haddad, Mansour, Alsalem, Mohammad, Saleh, Tareq, Jaffal, Sahar M., Barakat, Noor A., El-Salem, Khalid

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a significant adverse effect of many anticancer drugs. Current strategies for the management of CIPN pain…”
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Anti-nociceptive effect of Arbutus andrachne L. methanolic leaf extract mediated by CB1, TRPV1 and PPARs in mouse pain models by Jaffal, Sahar M., Oran, Sawsan A., Alsalem, Mohammad

“…Arbutus andrachne  L. is a medicinal plant that grows in Jordan and has many valuable effects. In the present study, the anti-nociceptive effect of…”
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Antinociceptive action of Achillea biebersteinii methanolic flower extract is mediated by interaction with cholinergic receptor in mouse pain models by Jaffal, Sahar M., Abbas, Manal A.

“…Achillea biebersteinii is a perennial aromatic herb that grows in the Mediterranean area. The leaves of this plant are used in foods as bittering and…”
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The desensitization of the transient receptor potential vanilloid 1 by nonpungent agonists and its resensitization by bradykinin by Alsalem, Mohammad, Aldossary, Sara A., Haddad, Mansour, Altarifi, Ahmad, Kalbouneh, Heba, Azab, Belal, Mustafa, Ayman G., Jaffal, Sahar M., El-Salem, Khalid

“…Transient receptor potential vanilloid type-1 (TRPV1) channels have crucial roles in inflammatory hyperalgesia. Different inflammatory mediators can modulate…”
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Gastroprotective activity of Loranthus acaciae flower extract in a rodent model of ethanol-induced ulcer by Abbas, Manal A, Kandil, Yasser I, Disi, Ahmad M, Jaffal, Sahar M

“…(Loranthaceae) is a perennial green semi-parasitic plant used in ethnopharmacological medicine for healing wounds. The protective effect of on gastric ulcer…”
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Anti-inflammatory and antipyretic potential of Arbutus andrachne L. methanolic leaf extract in rats by Jaffal, Sahar, Oran, Sawsan, Alsalem, Mohammad

“…Objective: To explore the anti-inflammatory and antipyretic effects of methanolic leaf extract from Arbutus andrachne and its mechanism of action. Methods: Paw…”
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Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound by Alsalem, Mohammad, Haddad, Mansour, Aldossary, Sara A., Kalbouneh, Heba, Altarifi, Ahmad, Jaffal, Sahar M., Abbas, Manal A., Aldaoud, Nour, El-Salem, Khalid

“…Osteoarthritis (OA) is characterized by cartilage degeneration, subchondral sclerosis, and pain. Cannabinoids have well-established anti-nociceptive properties…”
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Cough reflex hypersensitivity: A role for neurotrophins by El-Hashim, Ahmed Z., Jaffal, Sahar M.

“…Cough is one of the most common complaints for which sufferers seek medical assistance. However, currently available drugs are not very effective in treating…”
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Evidence for the involvement of opioid receptor in Ajuga chamaepitys action in chemical and thermal models of pain in BALB/c mice by Jaffal, Sahar M., Abbas, Manal A., Alsalem, Mohammad, Al-Najjar, Belal O.

“…Ajuga chamaepitys is a small herbaceous annual or biannual plant that belongs to Lamiaceae family. It grows in Europe and Eastern parts of the Mediterranean…”
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Anti-tussive and bronchodilator mechanisms of action for the enaminone E121 by El-Hashim, Ahmed Z., Edafiogho, Ivan O., Jaffal, Sahar M., Yousif, Mariam H., Ezeamuzie, Charles I., Kombian, Samuel B.

“…In this study, we investigated whether the enaminone, E121, has anti-tussive effects in a guinea pig model of cough, and if so, whether this effect is mediated…”
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Nerve growth factor enhances cough via a central mechanism of action by El-Hashim, Ahmed Z., Jaffal, Sahar M., Al-Rashidi, Fatma T., Luqmani, Yunus A., Akhtar, Saghir

“…The mechanisms involved in enhanced cough induced by central and inhaled NGF in guinea pigs were investigated. Cough and airway function were assessed by…”
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Interaction of the synthetic cannabinoid WIN55212 with tramadol on nociceptive thresholds and core body temperature in a chemotherapy-induced peripheral neuropathy pain model by Haddad, Mansour, Alsalem, Mohammad, Saleh, Tareq, Jaffal, Sahar M., Barakat, Noor A., El-Salem, Khalid

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a significant adverse effect of many anticancer drugs. Current strategies for the management of CIPN pain…”
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Antinociceptive Action of Moringa peregrina is Mediated by an Interaction with [[alpha].sub.2]-Adrenergic Receptor by Jaffal, Sahar M, Al-Najjar, Belal O, Abbas, Manal A, Oran, Sawsan A

“…Background: Moringa peregrina (M. peregrina) is an edible, drought-resistant tree that is native to semi-arid countries. It is used as a painkiller in folk…”
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