Search Results - "Jafarlou, Mahdi"
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Unveiling the menace: a thorough review of potential pandemic fungal disease
Published in Frontiers in fungal biology (22-04-2024)“…Fungal diseases have emerged as a significant global health threat, with the potential to cause widespread outbreaks and significant morbidity and mortality…”
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2
The regulatory role of autophagy-related miRNAs in lung cancer drug resistance
Published in Biomedicine & pharmacotherapy (01-04-2022)“…Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular components and has a crucial role in the pathogenesis and drug…”
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3
CTLA-4 silencing in dendritic cells loaded with colorectal cancer cell lysate improves autologous T cell responses in vitro
Published in Frontiers in immunology (01-08-2022)“…Dendritic cell (DC)-based immunotherapy has increased interest among anti-cancer immunotherapies. Nevertheless, the immunosuppressive mechanisms in the tumor…”
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4
The emerging role of noncoding RNAs in systemic lupus erythematosus: new insights into the master regulators of disease pathogenesis
Published in Therapeutic Advances in Chronic Disease (01-01-2023)“…Auto-immune diseases are a form of chronic disorders in which the immune system destroys the body’s cells due to a loss of tolerance to self-antigens. Systemic…”
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5
Inflammatory reflex disruption in COVID‐19
Published in Clinical & experimental neuroimmunology (01-11-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was identified in Wuhan, China, in late 2019 and caused coronavirus disease 2019 (COVID‐19), which…”
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The Effects of siRNA-Mediated Gene Silencing of Alpha-7 Nicotinic Acetylcholine Receptors on Drug Resistance to Oxaliplatin in Colorectal Cancer Cells
Published in Biology bulletin of the Russian Academy of Sciences (01-12-2022)“…The role of alpha-7 nicotinic acetylcholine receptor (α7nAchR) in colorectal cancer (CRC) chemoresistance, especially in Oxaliplatin (OXA)-resistant cells, has…”
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7
Fig Juice Fermented with Lactic Acid Bacteria as a Nutraceutical Product
Published in Pharmaceutical Sciences (01-12-2016)“…[...]samples were inoculated with three species of probiotics (6 log CFU/ml) separately and incubated aerobically at 30 °C for 72 hours. [...]samples were…”
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Nicotinic Acetylcholine Receptor Subunit Alpha-7 Mediates PD-L1 and CTLA-4 Expression in HepG2 Cells
Published in ImmunoAnalysis (28-12-2021)“…Background: The liver is the largest solid organ in the body and has several unique immunological roles. The alpha7 subtype of nicotinic acetylcholine receptor…”
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9
Hemoperfusion Therapy’s Efficiency in Reducing Serum IL-6 Levels and Disease Severity in COVID-19 Patients
Published in ImmunoAnalysis (26-12-2022)“…Background: Interleukin (IL)-6, one of the inflammatory mediators involved in severe cases of coronavirus disease-19 (COVID-19), has been implicated in the…”
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10
Targeting Nanog expression increased Cisplatin chemosensitivity and inhibited cell migration in Gastric cancer cells
Published in Experimental cell research (15-08-2023)“…Regardless of significant advances in cancer treatment, gastric cancer (GC) incidence rate is increasing worldwide. As one of the main transcription factors…”
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Unraveling dedifferentiation and metastasis traces in pancreatic ductal adenocarcinoma ductal cells: Insights from single-cell RNA sequencing analysis of ITGB4 and C19orf33
Published in Pathology, research and practice (01-01-2024)“…Pancreatic Ductal Adenocarcinoma (PDAC) ranks among the most prevalent gastrointestinal malignancies, with risk factors including smoking, alcohol abuse,…”
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12
Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development
Published in Gene (20-02-2024)“…As inhibitory immune checkpoint molecules, cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) and V-domain Ig suppressor of T-cell activation (VISTA) can be…”
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13
Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells
Published in Experimental cell research (01-08-2023)“…Glioblastoma multiforme (GBM) is among the malignant brain tumors of the central nervous system (CNS). The survival of this disease is about 14 months after…”
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14
The role of probiotic supplementation in inflammatory biomarkers in adults: an umbrella meta-analysis of randomized controlled trials
Published in Inflammopharmacology (01-10-2023)“…Objective Despite the increasing evidence for probiotics’ anti-inflammatory effects, the results of meta-analyses remain inconsistent. The present umbrella…”
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15
The Combination of PD-L1 and CTLA-4 Suppression Significantly Decreased the Expression Levels of Cancer Stem Cell Factors in the Pancreatic Cancer Cell Line
Published in ImmunoAnalysis (26-06-2023)“…Background: It is thought that a limited number of aberrant cancer stem cells (CSCs), which encourage carcinogenesis, tumor metastasis, and treatment…”
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The modulatory role of dendritic cell-T cell cross-talk in breast cancer: Challenges and prospects
Published in Advances in medical sciences (01-09-2022)“…Antigen recognition and presentation are highlighted as the first steps in developing specialized antigen responses. Dendritic cells (DCs) are outstanding…”
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Regulatory Effects of Long Non-coding RNAs on Th17/Treg Differentiation and Imbalance
Published in Iranian journal of allergy, asthma, and immunology (28-12-2023)“…Scientific research over the past decades has proven the pivotal role of long non-coding RNAs (LncRNAs) in regulating gene expression. The immune responses are…”
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Enhancement of chemosensitivity by simultaneously silencing of Mcl-1 and Survivin genes using small interfering RNA in human myelomonocytic leukaemia
Published in Artificial cells, nanomedicine, and biotechnology (01-12-2018)“…Acute myeloid leukaemia (AML) is a genetically heterogeneous, severe and rapidly progressing disease triggered by blocking granulocyte or monocyte…”
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Regulation of Dendritic Cell Functions by Vitamins as Promising Therapeutic Strategy for Immune System Disorders
Published in Advanced biology (01-12-2023)“…A functional immune system is crucial for a healthy life, protecting from infections, tumors, or autoimmune disorders; these are accomplished by the…”
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High cholesterol diet increases expression of cholesterol 24-hydroxylase and BACE1 in rat hippocampi : implications for the effect of diet cholesterol on memory
Published in Iranian red crescent medical journal (01-12-2016)“…Background: Abnormal cholesterol homeostasis is associated with the pathogenesis of neurodegenerative disease and cognitive impairment. Objectives: Our…”
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