Search Results - "Jaecklein, Karin"
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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
Published in Cell stem cell (06-01-2022)“…Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness. Due to the scarcity of HSCs, technical challenges have limited our…”
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Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells
Published in Nature cell biology (01-07-2022)“…Bone marrow haematopoietic stem cells (HSCs) are vital for lifelong maintenance of healthy haematopoiesis. In inbred mice housed in gnotobiotic facilities, the…”
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Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells
Published in Blood (10-06-2021)“…Hematopoietic stem cells (HSCs) and distinct multipotent progenitor (MPP) populations (MPP1-4) contained within the Lin−Sca-1+c-Kit+ (LSK) compartment have…”
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3171 – MOUSE MULTIPOTENT PROGENITOR 5 CELLS ARE LOCATED AT THE INTERPHASE BETWEEN HEMATOPOIETIC STEM AND PROGENITOR CELLS
Published in Experimental hematology (2022)“…Hematopoietic stem cells (HSCs) are located at the top of the hematopoietic hierarchy and, together with multipotent progenitors (MPPs), are contained within…”
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GPRC5C drives branched-chain amino acid metabolism in leukemogenesis
Published in Blood advances (26-12-2023)“…Leukemia stem cells (LSCs) share numerous features with healthy hematopoietic stem cells (HSCs). G-protein coupled receptor family C group 5 member C (GPRC5C)…”
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