Search Results - "Jae Min Shin"

Cancer Drug Response Profile scan (CDRscan): A Deep Learning Model That Predicts Drug Effectiveness from Cancer Genomic Signature by Chang, Yoosup, Park, Hyejin, Yang, Hyun-Jin, Lee, Seungju, Lee, Kwee-Yum, Kim, Tae Soon, Jung, Jongsun, Shin, Jae-Min

“…In the era of precision medicine, cancer therapy can be tailored to an individual patient based on the genomic profile of a tumour. Despite the ever-increasing…”
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Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways by Yang, Hyun-Woo, Lee, Seoung-Ae, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man

“…Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue…”
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KinScan: AI-based rapid profiling of activity across the kinome by Brahma, Rahul, Shin, Jae-Min, Cho, Kwang-Hwi

“…Abstract Kinases play a vital role in regulating essential cellular processes, including cell cycle progression, growth, apoptosis, and metabolism, by…”
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Inhibitory effect of doxycycline conjugated with deoxycholic acid and polyethylenimine conjugate on nasal fibroblast differentiation and extracellular production by Shin, Jae-Min, Yang, Hyun-Woo, Lim, Su-Yeon, Jeong, Ji-Hoon, Park, Il-Ho

“…Chronic rhinosinusitis (CRS) is an inflammatory disease affecting the sinuses or nose. Persistent inflammatory responses can lead to tissue remodeling, which…”
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Glycolytic reprogramming is involved in tissue remodeling on chronic rhinosinusitis by Jo, Min-Sik, Yang, Hyun-Woo, Park, Joo-Hoo, Shin, Jae-Min, Park, Il-Ho

“…Glycolytic reprogramming is a key feature of chronic inflammatory disease. Extracellular matrix (ECM) produced by myofibroblasts plays an important role in…”
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Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts by Kim, Jin Ah, Cho, Jae Hoon, Park, Il-Ho, Shin, Jae-Min, Lee, Seoung-Ae, Lee, Heung-Man

“…Diesel exhaust particles (DEP) are a major source of air pollution. Nasal fibroblasts are known to produce various cytokines and chemokines. The aim of this…”
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Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium by Park, Il-Ho, Kang, Ju-Hyung, Shin, Jae-Min, Lee, Heung-Man

“…Tissue remodeling is believed to cause recalcitrant chronic rhinosinusitis (CRS). Epithelial-mesenchymal transition (EMT) is a novel clinical therapeutic…”
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AiKPro: deep learning model for kinome-wide bioactivity profiling using structure-based sequence alignments and molecular 3D conformer ensemble descriptors by Park, Hyejin, Hong, Sujeong, Lee, Myeonghun, Kang, Sungil, Brahma, Rahul, Cho, Kwang-Hwi, Shin, Jae-Min

“…The discovery of selective and potent kinase inhibitors is crucial for the treatment of various diseases, but the process is challenging due to the high…”
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DNMTs Are Involved in TGF-β1-Induced Epithelial-Mesenchymal Transitions in Airway Epithelial Cells by Park, Joo-Hoo, Shin, Jae-Min, Yang, Hyun-Woo, Park, Il-Ho

“…Chronic rhinosinusitis (CRS) pathogenesis is closely related to tissue remodeling, including epithelial-mesenchymal transition (EMT). Epigenetic mechanisms…”
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Prediction of human cytochrome P450 inhibition using bio‐selectivity induced deep neural network by Park, Hyejin, Brahma, Rahul, Shin, Jae‐Min, Cho, Kwang‐Hwi

“…Since the successful debut of AlphaGo, deep learning (DL) techniques have been applied to almost all areas of data sciences and are achieving remarkable…”
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Changing Trends in the Clinical Characteristics and Treatment Strategies for Odontogenic Sinusitis Over the Past 10 Years by Shin, Jae-Min, Kim, Su-Jong, Lee, Heung-Man, Park, Il-Ho

“…Objectives The incidence of odontogenic sinusitis has been gradually increasing due to the recent increases in invasive dental procedures. This study aimed to…”
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In Silico Screening and Optimization of Cell-Penetrating Peptides Using Deep Learning Methods by Park, Hyejin, Park, Jung-Hyun, Kim, Min Seok, Cho, Kwangmin, Shin, Jae-Min

“…Cell-penetrating peptides (CPPs) have great potential to deliver bioactive agents into cells. Although there have been many recent advances in CPP-related…”
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miR-29b Regulates TGF-β1-Induced Epithelial-Mesenchymal Transition by Inhibiting Heat Shock Protein 47 Expression in Airway Epithelial Cells by Shin, Jae-Min, Park, Joo-Hoo, Yang, Hyun-Woo, Moon, Jee Won, Lee, Heung-Man, Park, Il-Ho

“…Tissue remodeling contributes to ongoing inflammation and refractoriness of chronic rhinosinusitis (CRS). During this process, epithelial-mesenchymal…”
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Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation by Park, Joo-Hoo, Choi, Yujin, Shin, Jae-Min, Yang, Hyun-Woo, Jeong, Seong-Ho, Park, Il-Ho

“…Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow…”
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Eosinophil-Derived Osteopontin Induces the Expression of Pro-Inflammatory Mediators and Stimulates Extracellular Matrix Production in Nasal Fibroblasts: The Role of Osteopontin in Eosinophilic Chronic Rhinosinusitis by Yang, Hyun-Woo, Park, Joo-Hoo, Jo, Min-Sik, Shin, Jae-Min, Kim, Dae Woo, Park, Il-Ho

“…Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis (CRS) and is a refractory or intractable disease. However, a reliable…”
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Position Tracking Techniques Using Multiple Receivers for Anti-Drone Systems by Shin, Jae-Min, Kim, Yu-Sin, Ban, Tae-Won, Choi, Suna, Kang, Kyu-Min, Ryu, Jong-Yeol

“…The need for drone traffic control management has emerged as the demand for drones increased. Particularly, in order to control unauthorized drones, the…”
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Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation by Moon, Jee Won, Choi, Seok-Youl, Kim, Su-Jong, Shin, Jae-Min, Park, Il-Ho

“…Background Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human…”
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Apigenin alleviates TGF-β1-induced nasal mucosa remodeling by inhibiting MAPK / NF-kB signaling pathways in chronic rhinosinusitis by Yang, Hyun-Woo, Kim, Hwee-Jin, Park, Joo-Hoo, Shin, Jae-Min, Lee, Heung-Man

“…Chronic rhinosinusitis is involved in tissue remodeling of nasal mucosa such as nasal myofibroblast differentiation and extracellular matrix production…”
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Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway by Lee, Seoung-Ae, Yang, Hyun-Woo, Um, Ji-Young, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man

“…To investigate the potential role of vitamin D (1,25(OH) 2 D 3 ) in preventing the development of nasal polyps, we examined the effect of vitamin D on…”
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Baicalin Down-Regulates IL-1β-Stimulated Extracellular Matrix Production in Nasal Fibroblasts by Shin, Jae-Min, Kang, Ju-Hyung, Lee, Seoung-Ae, Park, Il-Ho, Lee, Heung-Man

“…Baicalin, a Chinese herbal medicine, has anti-fibrotic and anti-inflammatory effects. The aims of present study were to investigate the effects of baicalin on…”
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