Search Results - "Jadidi‐Niaragh, F."
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Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis
Published in Scandinavian journal of immunology (01-07-2011)“…Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of demyelination and axonal lesion mediated by CD4+ T cells with a…”
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Rheumatologic complications in a cohort of 227 patients with common variable immunodeficiency
Published in Scandinavian journal of immunology (01-05-2018)“…Common variable immunodeficiency (CVID) is the most prevalent symptomatic type of human primary immunodeficiency diseases (PID). Clinically, CVID is…”
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The Role of Natural Killer Cells in Alzheimer's Disease
Published in Scandinavian journal of immunology (01-11-2012)“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and selective neuronal death in the brain. The…”
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The profile of IL-4, IL-5, IL-10 and GATA3 in patients with LRBA deficiency and CVID with no known monogenic disease: Association with disease severity
Published in Allergologia et immunopathologia (01-03-2019)“…Common variable immunodeficiency (CVID) is the most common symptomatic form of primary immunodeficiency (PID). LPS-responsive beige-like anchor protein (LRBA)…”
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Nanoparticles and targeted drug delivery in cancer therapy
Published in Immunology letters (01-10-2017)“…•Nanomedicine improved the current immunotherapeutic approaches.•Nanomaterials can reduce the adverse effects of current anti-cancer drugs.•Targeted drug…”
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The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer
Published in Biomedicine & pharmacotherapy (01-12-2018)“…•IL-6 and its associated signaling promote cancer progression.•Targeting IL-6 signaling axis can arrest tumor growth.•Blockage of IL-6 and IL-6R can be…”
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CD73 as a potential opportunity for cancer immunotherapy
Published in Expert opinion on therapeutic targets (01-02-2019)“…Cancer cells apply various mechanisms to induce and enhance immune escape. The complex network of immune-response modulating factors in the tumor…”
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Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer
Published in Journal of cellular physiology (01-03-2018)“…Tumor cells overcome anti‐tumor responses in part through immunosuppressive mechanisms. There are several immune modulatory mechanisms. Among them, adenosine…”
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Prostaglandin E2 as a potent therapeutic target for treatment of colon cancer
Published in Prostaglandins & other lipid mediators (01-10-2019)“…•Colon cancer in one of the main health-related problems which is incurable particularly in advanced stages.•Prostanoids and particularly prostaglandin E2…”
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The imbalance of Th17/Treg axis involved in the pathogenesis of preeclampsia
Published in Journal of cellular physiology (01-04-2019)“…Problem Inappropriate activation of the immune system, particularly the imbalance of T‐helper type 17 (Th17)/regulatory T (Treg) cells is thought to play…”
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CDK1 in Breast Cancer: Implications for Theranostic Potential
Published in Anti-cancer agents in medicinal chemistry (01-01-2020)“…Breast cancer has been identified as one of the main cancer-related deaths among women during some last decades. Recent advances in the introduction of novel…”
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Oncostatin M: A mysterious cytokine in cancers
Published in International immunopharmacology (01-01-2021)“…•OSM is a tumor site dominant cytokine associated with the immunopathogenesis of numerous cancers.•STAT3 acts as the main transcription factor in the OSM…”
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Blockage of immune checkpoint molecules increases T‐cell priming potential of dendritic cell vaccine
Published in Immunology (01-01-2020)“…Summary Dendritic cell (DC) ‐based cancer immunotherapy is one of the most important anti‐cancer immunotherapies, and has been associated with variable…”
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Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review
Published in Clinical reviews in allergy & immunology (01-12-2020)“…Activated phosphoinositide 3-kinase delta syndrome (APDS) is a novel primary immunodeficiency (PID) caused by heterozygous gain of function mutations in PI3Kδ…”
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Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway
Published in International journal of biological macromolecules (15-07-2019)“…Adenosine and its receptors are novel promising targets for cancer immunotherapy. In here, we aimed to evaluate the efficacy of Polyethylene glycol…”
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PD-L1/PD-1 axis as a potent therapeutic target in breast cancer
Published in Life sciences (1973) (15-04-2020)“…Although both the incidence and the mortality rate of breast cancer is rising, there is no potent and practical option for the treatment of these patients,…”
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The prognostic and therapeutic potential of vimentin in colorectal cancer
Published in Molecular biology reports (01-12-2024)“…Several cells and molecules in the tumor microenvironment have been introduced as effective factors in the prognosis and progression of colorectal cancer. As a…”
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Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression
Published in International journal of biological macromolecules (15-04-2020)“…The immunosuppressive nature of the tumor microenvironment is a critical problem that should be considered before the design of immunotherapies. Interleukin…”
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Mechanisms of tumor cell resistance to the current targeted-therapy agents
Published in Tumor biology (01-08-2016)“…Resistance to chemotherapy agents is a major challenge infront of cancer patient treatment and researchers. It is known that several factors, such as multidrug…”
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