Search Results - "Jacquet, Sebastien"

Identification of Cardiac Myosin-binding Protein C as a Candidate Biomarker of Myocardial Infarction by Proteomics Analysis by Jacquet, Sebastien, Yin, Xiaoke, Sicard, Pierre, Clark, James, Kanaganayagam, Gajen S., Mayr, Manuel, Marber, Michael S.

“…Acute myocardial infarction (AMI) is a common cause of death for which effective treatments are available provided that diagnosis is rapid. The current…”
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The Role of RIP2 in p38 MAPK Activation in the Stressed Heart by Jacquet, Sebastien, Nishino, Yasuhiro, Kumphune, Sarawut, Sicard, Pierre, Clark, James E., Kobayashi, Koichi S., Flavell, Richard A., Eickhoff, Jan, Cotten, Matt, Marber, Michael S.

“…The activation of p38 MAPK by dual phosphorylation aggravates myocardial ischemic injury and depresses cardiac contractile function. SB203580, an…”
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Combined effects of defoliation and water stress on pine growth and non-structural carbohydrates by Jacquet, Jean-Sébastien, Bosc, Alexandre, O'Grady, Anthony, Jactel, Hervé

“…Climate change is expected to increase both pest insect damage and the occurrence of severe drought. There is therefore a need to better understand the…”
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Defoliation by processionary moth significantly reduces tree growth: a quantitative review by Jacquet, Jean-Sébastien, Orazio, Christophe, Jactel, Hervé

“…• CONTEXT: Forests are important carbon sinks, but increasing temperatures may favour increases in insect populations, resulting in greater damage to trees…”
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In situ evaluation of thermostat setback scenarios for all-electric single-family houses in cold climate by Jacquet, Sébastien, Le Bel, Célyn, Monfet, Danielle

“…•In-situ measurements were used to evaluate 4°C night, day and dual thermostat setbacks.•At the house level, savings of 10% were possible for day and night…”
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Pine growth response to processionary moth defoliation across a 40-year chronosequence by Jacquet, Jean-Sébastien, Bosc, Alexandre, O’Grady, Anthony P., Jactel, Hervé

“…► Pine processionary moth and artificial defoliations caused significant growth losses. ► Radial growth loss was proportional to defoliation intensity and…”
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Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists by Amaudrut, Jérôme, Argiriadi, Maria A., Barth, Martine, Breinlinger, Eric C., Bressac, Didier, Broqua, Pierre, Calderwood, David J., Chatar, Mohamed, Cusack, Kevin P., Gauld, Stephen B., Jacquet, Sébastien, Kamath, Rajesh V., Kort, Michael E., Lepais, Valérie, Luccarini, Jean-Michel, Masson, Philippe, Montalbetti, Christian, Mounier, Laurent, Potin, Dominique, Poupardin, Olivia, Rouaud, Sylvie, Spitzer, Luc, Wallace, Craig D.

“…[Display omitted] A high-throughput screen against Inventiva’s compound library using a Gal4/RORγ-LBD luciferase reporter gene assay led to the discovery of a…”
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Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis by Barbaras, Ronald, Martinez, Laurent O, Jacquet, Sébastien, Esteve, Jean-Pierre, Rolland, Corinne, Cabezón, Elena, Champagne, Eric, Pineau, Thierry, Georgeaud, Valérie, Walker, John E, Tercé, François, Collet, Xavier, Perret, Bertrand

“…The effect of high-density lipoprotein (HDL) in protecting against atherosclerosis is usually attributed to its role in 'reverse cholesterol transport'. In…”
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Inhibition of Interleukin-23-Mediated Inflammation with a Novel Small Molecule Inverse Agonist of ROR γ t by Gauld, Stephen B, Jacquet, Sebastien, Gauvin, Donna, Wallace, Craig, Wang, Yibing, McCarthy, Richard, Goess, Christian, Leys, Laura, Huang, Susan, Su, Zhi, Edelmayer, Rebecca, Wetter, Joseph, Salte, Katherine, McGaraughty, Steven P, Argiriadi, Maria A, Honore, Prisca, Luccarini, Jean-Michel, Bressac, Didier, Desino, Kelly, Breinlinger, Eric, Cusack, Kevin, Potin, Dominique, Kort, Michael E, Masson, Philippe J

“…Blockade of interleukin (IL)-23 or IL-17 with biologics is clinically validated as a treatment of psoriasis. However, the clinical impact of targeting other…”
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Glycogen Synthase Kinase-3 Inactivation Is Not Required for Ischemic Preconditioning or Postconditioning in the Mouse by Nishino, Yasuhiro, Webb, Ian G, Davidson, Sean M, Ahmed, Aminul I, Clark, James E, Jacquet, Sebastien, Shah, Ajay M, Miura, Tetsuji, Yellon, Derek M, Avkiran, Metin, Marber, Michael S

“…The inactivation of glycogen synthase kinase-3β (GSK-3β) is proposed as the event integrating protective pathways initiated by preconditioning and other…”
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A Chemical Genetic Approach Reveals That p38α MAPK Activation by Diphosphorylation Aggravates Myocardial Infarction and Is Prevented by the Direct Binding of SB203580 by Kumphune, Sarawut, Bassi, Rekha, Jacquet, Sebastien, Sicard, Pierre, Clark, James E., Verma, Sharwari, Avkiran, Metin, O’Keefe, Stephen J., Marber, Michael S.

“…The use of nonselective pharmacological inhibitors has resulted in controversy regarding the mechanism and consequences of p38 activation during myocardial…”
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The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning by Sicard, Pierre, Clark, James E, Jacquet, Sebastien, Mohammadi, Shahrooz, Arthur, J. Simon C, O'Keefe, Stephen J, Marber, Michael S

“…Abstract Numerous studies show that pharmacological inhibition of p38 mitogen-activated protein kinases (p38s) before lethal ischemia prevents conditioning…”
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Cyclin towards infarction by Jacquet, Sebastien, Marber, Michael S

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Pharmacological postconditioning effect of muramyl dipeptide is mediated through RIP2 and TAK1 by Sicard, Pierre, Jacquet, Sebastien, Kobayashi, Koichi S., Flavell, Richard A., Marber, Michael S.

“…Aims Despite their ability to cause septic shock and myocardial dysfunction, components of Gram-negative bacterial cell walls, like lipopolysaccharide, have…”
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Activation of p38 Mitogen-Activated Protein Kinase Contributes to the Early Cardiodepressant Action of Tumor Necrosis Factor by Bellahcene, Mohamed, Jacquet, Sebastien, Cao, Xue B., Tanno, Masaya, Haworth, Robert S., Layland, Joanne, Kabir, Alamgir M., Gaestel, Matthias, Davis, Roger J., Flavell, Richard A., Shah, Ajay M., Avkiran, Metin, Marber, Michael S.

“…Activation of p38 Mitogen-Activated Protein Kinase Contributes to the Early Cardiodepressant Action of Tumor Necrosis Factor Mohamed Bellahcene, Sebastien…”
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Pharmacological postconditioning effect of muramyl dipeptide is mediated through RIP2 and TAK1: Spotlight Issue on Cardiac Protection by SICARD, Pierre, JACQUET, Sebastien, KOBAYASHI, Koichi S, FLAVELL, Richard A, MARBER, Michael S

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A Chemical Genetic Approach Reveals That p38α MAPK Activation by Diphosphorylation Aggravates Myocardial Infarction and Is Prevented by the Direct Binding of SB203580 by Sarawut Kumphune, Rekha Bassi, Sebastien Jacquet, Pierre Sicard, James E. Clark, Sharwari Verma, Metin Avkiran, Stephen J. O'Keefe, Michael S. Marber

“…The use of nonselective pharmacological inhibitors has resulted in controversy regarding the mechanism and consequences of p38 activation during myocardial…”
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The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia by Jacquet, Sebastien, Zarrinpashneh, Elham, Chavey, Audrey, Ginion, Audrey, Leclerc, Isabelle, Viollet, Benoit, Rutter, Guy A., Bertrand, Luc, Marber, Michael S.

“…Abstract Objective p38 mitogen-activated protein kinase (p38 MAPK) and AMP-activated protein kinase (AMPK) are activated by, and influence sensitivity to,…”
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The relationship between P38–MAPK and AMPK during myocardial ischaemia by Jacquet, Sebastien, Zarrinpashneh, Elham, Chavey, Audrey, Leclerc, Isabelle, Rutter, Guy A, Bertrand, Luc, Marber, Michael S

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The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning by Sicard, Pierre, Clark, James E, Jacquet, Sebastien, Mohammadi, Shahrooz, Arthur, J Simon C, O'Keefe, Stephen J, Marber, Michael S

“…Numerous studies show that pharmacological inhibition of p38 mitogen-activated protein kinases (p38s) before lethal ischemia prevents conditioning. However,…”
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