Search Results - "Jacques, I."

Glutamate transporters: confining runaway excitation by shaping synaptic transmission by Wadiche, Jacques I, Tzingounis, Anastassios V

“…Traditionally, glutamate transporters have been viewed as membrane proteins that harness the electrochemical gradient to slowly transport glutamate from the…”
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T-Type Ca2+ Channels Mediate a Critical Period of Plasticity in Adult-Born Granule Cells by Kennedy, William M, Gonzalez, Jose Carlos, Lee, Haeun, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Adult-born granule cells (abGCs) exhibil a transient period of elevated synaptic plasticity that plays an important role in hippocampal function. Various…”
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T-Type Ca 2+ Channels Mediate a Critical Period of Plasticity in Adult-Born Granule Cells by Kennedy, William M, Gonzalez, Jose Carlos, Lee, Haeun, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Adult-born granule cells (abGCs) exhibit a transient period of elevated synaptic plasticity that plays an important role in hippocampal function. Various…”
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The ubiquitous nature of multivesicular release by Rudolph, Stephanie, Tsai, Ming-Chi, von Gersdorff, Henrique, Wadiche, Jacques I

“…Highlights • Multivesicular release (MVR) enhances the reliability of synaptic transmission throughout the brain. • MVR controls local synaptic integration and…”
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Afferent convergence to a shared population of interneuron AMPA receptors by Pennock, Reagan L., Coddington, Luke T., Yan, Xiaohui, Overstreet-Wadiche, Linda, Wadiche, Jacques I.

“…Precise alignment of pre- and postsynaptic elements optimizes the activation of glutamate receptors at excitatory synapses. Nonetheless, glutamate that…”
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Distinct determinants of sparse activation during granule cell maturation by Dieni, Cristina V, Nietz, Angela K, Panichi, Roberto, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Adult neurogenesis continually produces a small population of immature granule cells (GCs) within the dentate gyrus. The physiological properties of immature…”
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GABA depolarization is required for experience-dependent synapse unsilencing in adult-born neurons by Chancey, Jessica H, Adlaf, Elena W, Sapp, Matthew C, Pugh, Phyllis C, Wadiche, Jacques I, Overstreet-Wadiche, Linda S

“…Neural activity enhances adult neurogenesis, enabling experience to influence the construction of new circuits. GABAA receptor-mediated depolarization of…”
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Unraveling Finite Size Effects on Magnetic Properties of Cobalt Nanoparticles by Eone II, Jacques R, Bengone, Olivier M, Goyhenex, Christine

“…Using first principle calculations, the problem of scaling magnetic properties in nanoparticles is addressed. To this aim, the local electronic structure is…”
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Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells by Chancey, Jessica H, Poulsen, David J, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Adult-generated granule cells (GCs) in the dentate gyrus must establish synapses with preexisting neurons to participate in network activity. To determine the…”
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Low excitatory innervation balances high intrinsic excitability of immature dentate neurons by Dieni, Cristina V., Panichi, Roberto, Aimone, James B., Kuo, Chay T., Wadiche, Jacques I., Overstreet-Wadiche, Linda

“…Persistent neurogenesis in the dentate gyrus produces immature neurons with high intrinsic excitability and low levels of inhibition that are predicted to be…”
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Desynchronization of Multivesicular Release Enhances Purkinje Cell Output by Rudolph, Stephanie, Overstreet-Wadiche, Linda, Wadiche, Jacques I.

“…The release of neurotransmitter-filled vesicles after action potentials occurs with discrete time courses: submillisecond phasic release that can be…”
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Constitutive and Synaptic Activation of GIRK Channels Differentiates Mature and Newborn Dentate Granule Cells by Gonzalez, Jose Carlos, Epps, S Alisha, Markwardt, Sean J, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Sparse neural activity in the dentate gyrus is enforced by powerful networks of inhibitory GABAergic interneurons in combination with low intrinsic…”
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Circadian regulation of dentate gyrus excitability mediated by G-protein signaling by Gonzalez, Jose Carlos, Lee, Haeun, Vincent, Angela M., Hill, Angela L., Goode, Lacy K., King, Gwendalyn D., Gamble, Karen L., Wadiche, Jacques I., Overstreet-Wadiche, Linda

“…The central circadian regulator within the suprachiasmatic nucleus transmits time of day information by a diurnal spiking rhythm driven by molecular clock…”
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The readily-releasable pool dynamically regulates multivesicular release by Vaden, Jada H, Banumurthy, Gokulakrishna, Gusarevich, Eugeny S, Overstreet-Wadiche, Linda, Wadiche, Jacques I

“…The number of neurotransmitter-filled vesicles released into the synaptic cleft with each action potential dictates the reliability of synaptic transmission…”
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Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission by Erlenhardt, Nadine, Yu, Hong, Abiraman, Kavitha, Yamasaki, Tokiwa, Wadiche, Jacques I., Tomita, Susumu, Bredt, David S.

“…AMPA receptor (AMPAR) complexes contain auxiliary subunits that modulate receptor trafficking and gating. In addition to the transmembrane AMPAR regulatory…”
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Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity by Jahr, Craig E, Wadiche, Jacques I

“…Glutamate transporters are responsible for clearing synaptically released glutamate from the extracellular space. If expressed at high enough densities,…”
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Climbing Fiber-Mediated Spillover Transmission to Interneurons Is Regulated by EAAT4 by Malhotra, Shreya, Banumurthy, Gokulakrishna, Pennock, Reagan L, Vaden, Jada H, Sugihara, Izumi, Overstreet-Wadiche, Linda, Wadiche, Jacques I

“…Neurotransmitter spillover is a form of communication not readily predicted by anatomic structure. In the cerebellum, glutamate spillover from climbing fibers…”
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Parvalbumin interneurons provide spillover to newborn and mature dentate granule cells by Vaden, Ryan J, Gonzalez, Jose Carlos, Tsai, Ming-Chi, Niver, Anastasia J, Fusilier, Allison R, Griffith, Chelsea M, Kramer, Richard H, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Parvalbumin-expressing interneurons (PVs) in the dentate gyrus provide activity-dependent regulation of adult neurogenesis as well as maintain inhibitory…”
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Adult-born neurons modify excitatory synaptic transmission to existing neurons by Adlaf, Elena W, Vaden, Ryan J, Niver, Anastasia J, Manuel, Allison F, Onyilo, Vincent C, Araujo, Matheus T, Dieni, Cristina V, Vo, Hai T, King, Gwendalyn D, Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…Adult-born neurons are continually produced in the dentate gyrus but it is unclear whether synaptic integration of new neurons affects the pre-existing…”
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New neurons don't talk back by Wadiche, Jacques I, Overstreet-Wadiche, Linda

“…GABAergic interneurons enforce highly sparse activity patterns in principal neurons of the dentate gyrus. In this issue of Neuron, Temprana et al. (2015) show…”
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