Search Results - "Jacoby, DB"

Expression of Tachykinins in Nonnociceptive Vagal Afferent Neurons during Respiratory Viral Infection in Guinea Pigs by Carr, Michael J, Hunter, Dawn D, Jacoby, David B, Undem, Bradley J

“…Immunohistochemistry was combined with retrograde labeling to characterize the effect of respiratory infection with Sendai virus on the number of Substance…”
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Non‐bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea‐pig model of allergic asthma by Buels, KS, Jacoby, DB, Fryer, AD

“…BACKGROUND AND PURPOSE Asthma is characterized by reversible bronchoconstriction and airway hyperreactivity. Although M3 muscarinic receptors mediate…”
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Upping the antedrug: is a novel anti‐inflammatory Toll‐like receptor 7 agonist also a bronchodilator? by Kaufman, EH, Jacoby, DB

“…In this issue of British Journal of Pharmacology, Biffen and colleagues present a novel Toll‐like receptor 7 (TLR7) antedrug to treat allergic disease that is…”
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Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase by Jacoby, D B, Tamaoki, J, Borson, D B, Nadel, J A

“…Ferret tracheal segments were infected with human influenza virus A/Taiwan/86 (H1N1) in vitro. After 4 days, the smooth muscle contractile responses to…”
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Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase by Dusser, D J, Jacoby, D B, Djokic, T D, Rubinstein, I, Borson, D B, Nadel, J A

“…We examined the effects of viral respiratory infection by Sendai virus on airway responsiveness to tachykinins in guinea pigs. We measured the change in total…”
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Autologous Skeletal myoblasts transplanted to ischemia-damaged myocardium in humans: Histological analysis of cell survival and differentiation by PAGANI, Francis D, DERSIMONIAN, Harout, AARONSON, Keith D, ZAWADZKA, Agatha, WETZEL, Kristie, EDGE, Albert S. B, JACOBY, Douglas B, DINSMORE, Jonathan H, WRIGHT, Susan, ARETZ, Tom H, EISEN, Howard J

“…We report histological analysis of hearts from patients with end-stage heart disease who were transplanted with autologous skeletal myoblasts concurrent with…”
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Increased function of inhibitory neuronal M 2 muscarinic receptors in diabetic rat lungs by Belmonte, Kristen E, Jacoby, David B, Fryer, Allison D

“…The function of inhibitory neuronal M 2 muscarinic receptors in diabetic rat lungs was investigated. Neuronal M 2 muscarinic receptors inhibit acetylcholine…”
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Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction by Fryer, Allison D, Stein, Louis H, Nie, Zhenying, Curtis, Damian E, Evans, Christopher M, Hodgson, Simon T, Jose, Peter J, Belmonte, Kristen E, Fitch, Erin, Jacoby, David B

“…Eosinophils cluster around airway nerves in patients with fatal asthma and in antigen-challenged animals. Activated eosinophils release major basic protein,…”
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Increased function of inhibitory neuronal M 2 muscarinic receptors in trachea and ileum of diabetic rats by Coulson, Fiona R, Jacoby, David B, Fryer, Allison D

“…Release of acetylcholine from parasympathetic nerves is inhibited by neuronal M 2 muscarinic receptors. The effects of streptozotocin‐induced diabetes on…”
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Abnormalities in neural control of smooth muscle in virus-infected airways by Jacoby, D B, Fryer, A D

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Virus-Induced Asthma Attacks by Jacoby, David B

“…Viral respiratory tract infections are a common cause of asthma attacks. Study of this phenomenon has revealed multiple mechanisms and contributed to…”
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Muscarinic receptors and control of airway smooth muscle by FRYER, A. D, JACOBY, D. B

“…Contraction of airway smooth muscle is mediated by M3 muscarinic receptors on the airway smooth muscle. However, there is no evidence suggesting that…”
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Viral infection increases contractile but not secretory responses to substance P in ferret trachea by Murray, T C, Jacoby, D B

“…Viral infection increases the airway smooth muscle response to substance P. This effect is due to decreased activity of neutral endopeptidase (EC 3.4.24.11),…”
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Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure by Subauste, M C, Jacoby, D B, Richards, S M, Proud, D

“…Rhinovirus infections cause over one third of all colds and are a contributing factor to exacerbations of asthma. To gain insights into the early biochemical…”
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Synergism between Rhinovirus Infection and Oxidant Pollutant Exposure Enhances Airway Epithelial Cell Cytokine Production by Spannhake, E. William, Sekhar P. M. Reddy, Jacoby, David B., Yu, Xiao-Ying, Saatian, Bahman, Tian, Jingyan

“…Of the several factors believed to exacerbate asthmatic symptoms, air pollution and viral infections are considered to be particularly important. Although…”
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Pathophysiology of airway viral infections by Jacoby, David B.

“…Viral infections are major causes of cough. Virus-induced changes in airway sensory nerve function include increased tachykinin expression and, more…”
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Eosinophil recruitment to the airway nerves by Jacoby, David B., Costello, Richard M., Fryer, Allison D.

“…Increased vagal reflexes contribute to bronchoconstriction in asthma. Antigen challenge of sensitized animals induces vagal hyperresponsiveness. This review…”
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Airway neural plasticity: the nerves they are a-changin by Jacoby, David B

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No evidence for infection of human cells with porcine endogenous retrovirus (PERV) after exposure to porcine fetal neuronal cells by DINSMORE, Jonathan H, MANHART, Carolyn, RAINERI, Ronald, JACOBY, Douglas B, MOORE, Alan

“…Recent demonstration of human cell infection in vitro with porcine endogenous retrovirus (PERV) has raised safety concerns for new therapies that involve…”
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The changing role of eosinophils in long-term hyperreactivity following a single ozone exposure by Yost, Bethany L, Gleich, Gerald J, Jacoby, David B, Fryer, Allison D

“…Ozone hyperreactivity over 24 h is mediated by blockade of inhibitory M(2) muscarinic autoreceptors by eosinophil major basic protein. Because eosinophil…”
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