Search Results - "Jacobson, Therese"
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Heavy metals and metalloids as a cause for protein misfolding and aggregation
Published in Biomolecules (Basel, Switzerland) (25-02-2014)“…While the toxicity of metals and metalloids, like arsenic, cadmium, mercury, lead and chromium, is undisputed, the underlying molecular mechanisms are not…”
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Quantitative analysis of glycerol accumulation, glycolysis and growth under hyper osmotic stress
Published in PLoS computational biology (01-06-2013)“…We provide an integrated dynamic view on a eukaryotic osmolyte system, linking signaling with regulation of gene expression, metabolic control and growth…”
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Expression of neutrophil SOD2 is reduced after lipopolysaccharide stimulation: a potential cause of neutrophil dysfunction in chronic kidney disease
Published in Nephrology, dialysis, transplantation (01-07-2011)“…Background. Neutrophils from patients with chronic kidney disease (CKD) are dysfunctional and thus a contributing factor to the risk of infections. The…”
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Enhancing Documentation of Pressure Ulcer Prevention Interventions: A Quality Improvement Strategy to Reduce Pressure Ulcers
Published in Journal of nursing care quality (01-07-2016)“…Prevention of hospital-acquired pressure ulcers requires the implementation of evidence-based interventions. A quality improvement project was conducted to…”
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Gene expression analysis using long-term preserved formalin-fixed and paraffin-embedded tissue of non-small cell lung cancer
Published in International journal of oncology (01-04-2011)“…This study was performed to evaluate RNA extraction and gene expression analysis of non-small cell lung cancer (NSCLC) using formalin-fixed and…”
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Comparison of Cervical Range-of-Motion Restriction and Craniofacial Tissue-Interface Pressure With 2 Adjustable and 2 Standard Cervical Collars
Published in Spine (Philadelphia, Pa. 1976) (01-03-2016)“…STUDY DESIGN.Randomized controlled trial. OBJECTIVE.The aim of the study was to compare and contrast the restrictiveness and tissue-interface pressure (TIP)…”
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Improving Quality by Taking Aim at Incontinence-Associated Dermatitis in Hospitalized Adults
Published in Medsurg nursing (01-05-2015)“…A practice-improvement project was launched to implement an evidence-based intervention bundle for incontinence-associated dermatitis (IAD) and evaluate its…”
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Patient safety improvement through in situ simulation interdisciplinary team training
Published in Urologic nursing (01-01-2014)“…In situ simulation is an education strategy that promotes patient safety and enhances interdisciplinary teamwork. When a patient is experiencing an acute…”
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Effects of urinary catheter education for patients undergoing prostatectomy
Published in Urologic nursing (01-11-2013)“…In a nonrandomized prospective study, significant decreases in patient anxiety with home urinary catheter management and in length of stay were reported when…”
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Radical nephrectomy with inferior vena cava (IVC) thrombectomy: implications for post-operative nursing care
Published in Urologic nursing (01-11-2010)“…The surgery required to remove a renal cell carcinoma with inferior vena cava (IVC) tumor thrombus is complex. IVC tumor thrombus is a complicating factor that…”
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Improving practice: efforts to reduce occipital pressure ulcers
Published in Journal of nursing care quality (01-07-2008)“…Cervical collars are necessary to stabilize the cervical spine of trauma patients but are known to contribute to the development of occipital pressure ulcers…”
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Clinical scenarios: enhancing the skill set of the nurse as a vigilant guardian
Published in The Journal of continuing education in nursing (01-08-2010)“…Patient safety is enhanced when nursing staff recognize and respond to subtle changes in a patient's condition. In this quality improvement project, simulated…”
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Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity
Published in Journal of cell science (01-06-2021)“…The toxic metalloid arsenic causes widespread misfolding and aggregation of cellular proteins. How these protein aggregates are formed in vivo, the mechanisms…”
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Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast
Published in Molecular and cellular biology (01-09-2017)“…Cadmium is a highly poisonous metal and is classified as a human carcinogen. While its toxicity is undisputed, the underlying in vivo molecular mechanisms are…”
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Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity
Published in Journal of cell science (04-06-2021)“…The toxic metalloid arsenic causes widespread misfolding and aggregation of cellular proteins. How these protein aggregates are formed in vivo , the mechanisms…”
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Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast
Published in Journal of cell science (2012)“…Several metals and metalloids profoundly affect biological systems, but their impact on the proteome and mechanisms of toxicity are not fully understood. Here,…”
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Wound, Ostomy, and Continence Nursing: Scope and Standards of WOC Practice, 2nd Edition: An Executive Summary
Published in Journal of wound, ostomy, and continence nursing (01-07-2018)“…Wound, ostomy, and continence (WOC) nursing was recognized as a nursing specialty by the American Nurses Association in February 2010, and the Society…”
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Glutathione serves an extracellular defence function to decrease arsenite accumulation and toxicity in yeast
Published in Molecular microbiology (01-06-2012)“…Summary Arsenic is an environmental toxin and a worldwide health hazard. Since this metalloid is ubiquitous in nature, virtually all living organisms require…”
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Reproductive effects of the endocrine disruptor fenarimol on a Baltic amphipod Monoporeia affinis
Published in Environmental toxicology and chemistry (01-04-2006)“…An endocrine disruptor, the fungicide fenarimol, was investigated regarding its effects on reproduction and hormone (ecdysteroid) levels in the deposit‐feeding…”
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