Search Results - "Jacobson, Stephen C"

Electroosmotic Flow in Nanofluidic Channels by Haywood, Daniel G, Harms, Zachary D, Jacobson, Stephen C

“…We report the measurement of electroosmotic mobilities in nanofluidic channels with rectangular cross sections and compare our results with theory. Nanofluidic…”
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Analytical Techniques to Characterize the Structure, Properties, and Assembly of Virus Capsids by Kondylis, Panagiotis, Schlicksup, Christopher J, Zlotnick, Adam, Jacobson, Stephen C

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Effect of Conical Nanopore Diameter on Ion Current Rectification by Kovarik, Michelle L, Zhou, Kaimeng, Jacobson, Stephen C

“…Asymmetric nanoscale conduits, such as conical track-etch pores, rectify ion current due to surface charge effects. To date, most data concerning this…”
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Characterization of Hepatitis B Virus Capsids by Resistive-Pulse Sensing by Zhou, Kaimeng, Li, Lichun, Tan, Zhenning, Zlotnick, Adam, Jacobson, Stephen C.

“…We report characterization of hepatitis B virus (HBV) capsids by resistive-pulse sensing through single track-etched conical nanopores formed in poly(ethylene…”
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In-Depth Compositional and Structural Characterization of N‑Glycans Derived from Human Urinary Exosomes by Song, Woran, Zhou, Xiaomei, Benktander, John D, Gaunitz, Stefan, Zou, Guozhang, Wang, Ziyu, Novotny, Milos V, Jacobson, Stephen C

“…The study of exosomes has become increasingly popular due to their potentially important biological roles. Urine can be used as an effective source of exosomes…”
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Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry by Zhao, Zhongchao, Wang, Joseph Che-Yen, Zhang, Mi, Lyktey, Nicholas A., Jarrold, Martin F., Jacobson, Stephen C., Zlotnick, Adam

“…Symmetrical protein complexes are ubiquitous in biology. Many have been re-engineered for chemical and medical applications. Viral capsids and their assembly…”
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Noc Corrals Migration of FtsZ Protofilaments during Cytokinesis in Bacillus subtilis by Yu, Yuanchen, Zhou, Jinsheng, Gueiros-Filho, Frederico J, Kearns, Daniel B, Jacobson, Stephen C

“…Bacteria that divide by binary fission form FtsZ rings at the geometric midpoint of the cell between the bulk of the replicated nucleoids. In , the DNA- and…”
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Structural Characterization of Serum N‑Glycans by Methylamidation, Fluorescent Labeling, and Analysis by Microchip Electrophoresis by Mitra, Indranil, Snyder, Christa M, Zhou, Xiaomei, Campos, Margit I, Alley, William R, Novotny, Milos V, Jacobson, Stephen C

“…To characterize the structures of N-glycans derived from human serum, we report a strategy that combines microchip electrophoresis, standard addition,…”
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The Min System Disassembles FtsZ Foci and Inhibits Polar Peptidoglycan Remodeling in Bacillus subtilis by Yu, Yuanchen, Zhou, Jinsheng, Dempwolff, Felix, Baker, Joshua D, Kearns, Daniel B, Jacobson, Stephen C

“…A microfluidic system coupled with fluorescence microscopy is a powerful approach for quantitative analysis of bacterial growth. Here, we measure parameters of…”
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A molecular breadboard: Removal and replacement of subunits in a hepatitis B virus capsid by Lee, Lye Siang, Brunk, Nicholas, Haywood, Daniel G., Keifer, David, Pierson, Elizabeth, Kondylis, Panagiotis, Wang, Joseph Che‐Yen, Jacobson, Stephen C., Jarrold, Martin F., Zlotnick, Adam

“…Hepatitis B virus (HBV) core protein is a model system for studying assembly and disassembly of icosahedral structures. Controlling disassembly will allow…”
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Comparative Profiling of N‑Glycans Isolated from Serum Samples of Ovarian Cancer Patients and Analyzed by Microchip Electrophoresis by Mitra, Indranil, Alley, William R, Goetz, John A, Vasseur, Jacqueline A, Novotny, Milos V, Jacobson, Stephen C

“…Ovarian cancer is the fifth leading cause of cancer-related mortalities for women in the United States and the most lethal gynecological cancer. Aberrant…”
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Conductivity-based detection techniques in nanofluidic devices by Harms, Zachary D, Haywood, Daniel G, Kneller, Andrew R, Jacobson, Stephen C

“…This review covers conductivity detection in fabricated nanochannels and nanopores. Improvements in nanoscale sensing are a direct result of advances in…”
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Short-Stalked Prosthecomicrobium hirschii Cells Have a Caulobacter-Like Cell Cycle by Williams, Michelle, Hoffman, Michelle D, Daniel, Jeremy J, Madren, Seth M, Dhroso, Andi, Korkin, Dmitry, Givan, Scott A, Jacobson, Stephen C, Brown, Pamela J B

“…The dimorphic alphaproteobacterium Prosthecomicrobium hirschii has both short-stalked and long-stalked morphotypes. Notably, these morphologies do not arise…”
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Surface-Charge Induced Ion Depletion and Sample Stacking near Single Nanopores in Microfluidic Devices by Zhou, Kaimeng, Kovarik, Michelle L, Jacobson, Stephen C

“…We report integrated nanopore/microchannel devices in which single nanopores are isolated between two microfluidic channels. The devices were formed by…”
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Microfluidic Devices for the High-Throughput Chemical Analysis of Cells by McClain, Maxine A, Culbertson, Christopher T, Jacobson, Stephen C, Allbritton, Nancy L, Sims, Christopher E, Ramsey, J. Michael

“…A microfluidic device is reported that integrated cell handling, rapid cell lysis, and electrophoretic separation and detection of fluorescent cytosolic dyes…”
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Preconcentration of Proteins on Microfluidic Devices Using Porous Silica Membranes by Foote, Robert S, Khandurina, Julia, Jacobson, Stephen C, Ramsey, J. Michael

“…Fluorescently labeled proteins were electrophoretically concentrated on microfabricated devices prior to separation and laser-induced fluorescence detection on…”
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N-Glycan Profiling by Microchip Electrophoresis to Differentiate Disease States Related to Esophageal Adenocarcinoma by Mitra, Indranil, Zhuang, Zexi, Zhang, Yuening, Yu, Chuan-Yih, Hammoud, Zane T, Tang, Haixu, Mechref, Yehia, Jacobson, Stephen C

“…We report analysis of N-glycans derived from disease-free individuals and patients with Barrett’s esophagus, high-grade dysplasia, and esophageal…”
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Electrophoretic Analysis of N-Glycans on Microfluidic Devices by Zhuang, Zexi, Starkey, Jason A, Mechref, Yehia, Novotny, Milos V, Jacobson, Stephen C

“…We report rapid and efficient electrophoretic separations of N-glycans on microfluidic devices. Using a separation length of 22 cm and an electric field…”
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Disassembly of Single Virus Capsids Monitored in Real Time with Multicycle Resistive-Pulse Sensing by Zhou, Jinsheng, Zlotnick, Adam, Jacobson, Stephen C

“…Virus assembly and disassembly are critical steps in the virus lifecycle; however, virus disassembly is much less well understood than assembly. For hepatitis…”
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High-Efficiency, Two-Dimensional Separations of Protein Digests on Microfluidic Devices by Ramsey, Jeremy D, Jacobson, Stephen C, Culbertson, Christopher T, Ramsey, J. Michael

“…High-efficiency, two-dimensional separations of tryptic digests were achieved using glass microfluidic devices. Following micellar electrokinetic…”
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