Search Results - "Jacobson, L E"

Postoperative Apnea, Bradycardia, and Oxygen Desaturation in Formerly Premature Infants: Prospective Comparison of Spinal and General Anesthesia by Krane, Elliot J., Haberkern, Charles M., Jacobson, Lawrence E.

“…Eighteen formerly premature infants scheduled for inguinal herniorrhaphy and who were less than 51 wk postconceptional age were assigned to either the general…”
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Rational Interleukin 2 Therapy for HIV Positive Individuals: Daily Low Doses Enhance Immune Function without Toxicity by Jacobson, Elizabeth Leef, Pilaro, Fairley, Smith, Kendall A.

“…When administered in high doses to HIV positive (HIV$^{+}$) individuals, interleukin 2 (IL-2) causes extreme toxicity and markedly increases plasma HIV levels…”
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Histone carbonylation in vivo and in vitro by Wondrak, G T, Cervantes-Laurean, D, Jacobson, E L, Jacobson, M K

“…Non-enzymic damage to nuclear proteins has potentially severe consequences for the maintenance of genomic integrity. Introduction of carbonyl groups into…”
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Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo by Rankin, P W, Jacobson, E L, Benjamin, R C, Moss, J, Jacobson, M K

“…The ADP-ribosyl moiety of NAD+ is consumed in reactions catalyzed by three classes of enzymes: poly(ADP-ribose) polymerase, protein…”
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trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against gamma-irradiation and N-methyl-N'-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyomavirus replicon by Küpper, J H, Müller, M, Jacobson, M K, Tatsumi-Miyajima, J, Coyle, D L, Jacobson, E L, Bürkle, A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Synthesis and Degradation of Cyclic ADP-Ribose by NAD Glycohydrolases by Kim, Hyuntae, Jacobson, Elaine L., Jacobson, Myron K.

“…Cyclic adenosine diphosphoribose (cADPR), a recently discovered metabolite of nicotinamide adenine dinucleotide (NAD), is a potent calcium-releasing agent…”
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Current helmet and protective equipment usage among previously injured ATV and motorcycle riders by Mangus, R S, Simons, C J, Jacobson, L E, Streib, E W, Gomez, G A

“…Injury recidivism among trauma patients may be related to an individual pattern of high risk behaviors. The extent to which an injury episode modifies this…”
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Oral Niacin Prevents Photocarcinogenesis and Photoimmunosuppression in Mice by Gensler, Helen L., Williams, Tedine, Huang, Arnold C., Jacobson, Elaine L.

“…Topical nicotinamide (niacinamide) has demonstrable preventive activity against photocarcinogenesis in mice. To better understand how this vitamin prevents…”
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The dose response of caudal morphine in children by KRANE, E. J, TYLER, D. C, JACOBSON, L. E

“…The authors compared the duration of analgesia and the frequency of side effects of three doses of caudal epidural morphine in children aged 1.2-7.9 yr. Caudal…”
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Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo by Lund, Frances E, Partida-Sánchez, Santiago, Cockayne, Debra A, Monard, Simon, Jacobson, Elaine L, Oppenheimer, Norman, Garvy, Beth, Kusser, Kim, Goodrich, Stephen, Howard, Maureen, Harmsen, Allen, Randall, Troy D

“…Cyclic ADP-ribose is believed to be an important calcium-mobilizing second messenger in invertebrate, mammalian and plant cells. CD38, the best-characterized…”
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Protein glycation by ADP-ribose: Studies of model conjugates by Cervantes-Laurean, Daniel, Minter, David E, Jacobson, Elaine L, Jacobson, Myron K

“…Protein glycation by hexoses has been implicated in the pathophysiology of a number of diseases as well as the aging process. Studies of ADP-ribose polymer…”
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Conversion of laparoscopic to open cholecystectomy : An analysis of risk factors by WIEBKE, E. A, PRUITT, A. L, HOWARD, T. J, JACOBSON, L. E, BROADIE, T. A, GOULET, R. J, CANAL, D. F

“…Identifying patients who are at risk for conversion from laparoscopic (LC) to open cholecystectomy (OC) has proven to be difficult. The purpose of this review…”
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A biomarker for the assessment of niacin nutriture as a potential preventive factor in carcinogenesis by Jacobson, E L, Jacobson, M K

“…The study of protective cellular responses to DNA damage has led to the working hypothesis that optimal niacin nutriture is a preventive factor in cancer…”
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Caudal Morphine for Postoperative Analgesia in Children: A Comparison with Caudal Bupivacaine and Intravenous Morphine by Krane, Elliot J., Jacobson, Lawrence E., Lynn, Anne M., Parrot, Carol, Tyler, Donald C.

“…We compared the efficacy, duration, and side effects of preservative-free morphine injected into the caudal space in children, with caudal bupivacaine and with…”
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Evaluating the role of niacin in human carcinogenesis by Jacobson, E.L., Dame, A.J., Pyrek, J.S., Jacobson, M.K.

“…Our understanding of the role of ADP-ribose polymer metabolism in limiting carcinogenic events and the dependence of this metabolism on cellular NAD levels…”
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Poly(ADP-ribose) Polymerase Null Mouse Cells Synthesize ADP-ribose Polymers by Shieh, W. Melissa, Amé, Jean-Christophe, Wilson, Mandala V., Wang, Zhao-Qi, Koh, David W., Jacobson, Myron K., Jacobson, Elaine L.

“…Poly(ADP-ribose) polymerase (PARP) (EC 2.4.2.30), the only enzyme known to synthesize ADP-ribose polymers from NAD+, is activated in response to DNA strand…”
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Position of cyclization in cyclic ADP-ribose by Kim, H, Jacobson, E L, Jacobson, M K

“…Cyclic adenosine diphosphoribose (cADPR) is a putative second messenger of calcium homeostasis synthesized from NAD by cleavage of the nicotinamide-ribose bond…”
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High resolution fractionation and characterization of ADP-ribose polymers by Kiehlbauch, C C, Aboul-Ela, N, Jacobson, E L, Ringer, D P, Jacobson, M K

“…Methods are described for the high resolution fractionation and characterization of ADP-ribose polymers. Polymers prepared in vitro using purified…”
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Endogenous polymers of ADP-ribose are associated with the nuclear matrix by Cardenas-Corona, M E, Jacobson, E L, Jacobson, M K

“…The metabolism of nuclear polymers of ADP-ribose has been implicated in several chromatin-associated processes. However, the distribution of endogenous…”
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Poly(ADP-ribose) metabolism in ultraviolet irradiated human fibroblasts by Jacobson, E L, Antol, K M, Juarez-Salinas, H, Jacobson, M K

“…Exposure of human fibroblasts to 5 J/m2 of UV light resulted in a rapid increase of up to 1500% in the intracellular content of poly(ADP-ribose) and a rapid…”
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