Search Results - "Jacobson, Ken"

The Lateral Organization and Mobility of Plasma Membrane Components by Jacobson, Ken, Liu, Ping, Lagerholm, B. Christoffer

“…Over the last several decades, an impressive array of advanced microscopic and analytical tools, such as single-particle tracking and nanoscopic fluorescence…”
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Nanoclustering as a dominant feature of plasma membrane organization by Garcia-Parajo, Maria F, Cambi, Alessandra, Torreno-Pina, Juan A, Thompson, Nancy, Jacobson, Ken

“…Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has…”
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Direct measurement of the lamellipodial protrusive force in a migrating cell by Prass, Marcus, Jacobson, Ken, Mogilner, Alex, Radmacher, Manfred

“…There has been a great deal of interest in the mechanism of lamellipodial protrusion (Pollard, T., and G. Borisy. 2003. CELL: 112:453-465). However, one of…”
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Lipid rafts: at a crossroad between cell biology and physics by Jacobson, Ken, Mouritsen, Ole G, Anderson, Richard G. W

“…Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this…”
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MAP kinases and cell migration by Huang, Cai, Jacobson, Ken, Schaller, Michael D

“…Recent studies have demonstrated that mitogen-activated protein kinases (MAPKs), including Jun N-terminus kinase (JNK), p38 and Erk, play crucial roles in cell…”
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Chromophore-assisted laser inactivation in cell biology by Jacobson, Ken, Rajfur, Zenon, Vitriol, Eric, Hahn, Klaus

“…Chromophore-assisted laser inactivation (CALI) is a technique whereby engineered proteins and dye molecules that produce substantial amounts of reactive oxygen…”
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Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus by Monteith, Andrew J., Kang, SunAh, Scott, Eric, Hillman, Kai, Rajfur, Zenon, Jacobson, Ken, Costello, M. Joseph, Vilen, Barbara J.

“…Defects in clearing apoptotic debris disrupt tissue and immunological homeostasis, leading to autoimmune and inflammatory diseases. Herein, we report that…”
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Actin-Myosin Viscoelastic Flow in the Keratocyte Lamellipod by Rubinstein, Boris, Fournier, Maxime F., Jacobson, Ken, Verkhovsky, Alexander B., Mogilner, Alex

“…The lamellipod, the locomotory region of migratory cells, is shaped by the balance of protrusion and contraction. The latter is the result of myosin-generated…”
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Compression and dilation of the membrane-cortex layer generates rapid changes in cell shape by Kapustina, Maryna, Elston, Timothy C, Jacobson, Ken

“…Rapid changes in cellular morphology require a cell body that is highly flexible yet retains sufficient strength to maintain structural integrity. We present a…”
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Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration by Yousefi, Nima, Jacobson, Ken, Huang, Cai, Ginsberg, Mark H, Rajfur, Zenon, Chen, Zaozao

“…Cell migration is a dynamic process that requires temporal and spatial regulation of integrin activation and focal adhesion assembly/disassembly. Talin, an…”
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Phospholipids Undergo Hop Diffusion in Compartmentalized Cell Membrane by Fujiwara, Takahiro, Ritchie, Ken, Murakoshi, Hideji, Jacobson, Ken, Kusumi, Akihiro

“…The diffusion rate of lipids in the cell membrane is reduced by a factor of 5-100 from that in artificial bilayers. This slowing mechanism has puzzled cell…”
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Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions by Kapustina, Maryna, Tsygankov, Denis, Zhao, Jia, Wessler, Timothy, Yang, Xiaofeng, Chen, Alex, Roach, Nathan, Elston, Timothy C, Wang, Qi, Jacobson, Ken, Forest, M Gregory

“…Cells transition from spread to rounded morphologies in diverse physiological contexts including mitosis and mesenchymal-to-amoeboid transitions. When these…”
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transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton by Chen, Yun, Veracini, Laurence, Benistant, Christine, Jacobson, Ken

“…It remains unclear how GPI-anchored proteins (GPIAPs), which lack cytoplasmic domains, transduce signals triggered by specific ligation. Such signal…”
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Spatial and Temporal Regulation of Focal Adhesion Kinase Activity in Living Cells by Cai, Xinming, Lietha, Daniel, Ceccarelli, Derek F., Karginov, Andrei V., Rajfur, Zenon, Jacobson, Ken, Hahn, Klaus M., Eck, Michael J., Schaller, Michael D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Direct, high-resolution measurement of furrow stiffening during division of adherent cells by Jacobson, Ken, Matzke, Rainer, Radmacher, Manfred

“…It is unclear whether cell division is driven by cortical relaxation outside the equatorial region or cortical contractility within the developing furrow…”
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Relationship of Lipid Rafts to Transient Confinement Zones Detected by Single Particle Tracking by Dietrich, Christian, Yang, Bing, Fujiwara, Takahiro, Kusumi, Akihiro, Jacobson, Ken

“…We examined the physical and chemical characteristics of transient confinement zones (TCZs) that are detected in single particle trajectories of molecules…”
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Methods to measure the lateral diffusion of membrane lipids and proteins by Chen, Yun, Lagerholm, B. Christoffer, Yang, Bing, Jacobson, Ken

“…In this chapter, we discuss methods to measure lateral mobility of membrane lipids and proteins using techniques based on the light microscope. These methods…”
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Cell migration by Trepat, Xavier, Chen, Zaozao, Jacobson, Ken

“…Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence,…”
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Spatiotemporal relationships between the cell shape and the actomyosin cortex of periodically protruding cells by Driscoll, Meghan K., Losert, Wolfgang, Jacobson, Ken, Kapustina, Maryna

“…We investigate the dynamics of cell shape and analyze the actin and myosin distributions of cells exhibiting cortical density traveling waves. These waves…”
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Dimensional and Mechanical Dynamics of Active and Stable Edges in Motile Fibroblasts Investigated by Using Atomic Force Microscopy by Rotsch, Christian, Jacobson, Ken, Radmacher, Manfred

“…The atomic force microscope (AFM) was employed to investigate the extension and retraction dynamics of protruding and stable edges of motile 3T3 fibroblasts in…”
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