Search Results - "Jacobson, D R"

Variant-Sequence Transthyretin (Isoleucine 122) in Late-Onset Cardiac Amyloidosis in Black Americans by Jacobson, Daniel R, Pastore, Raymond D, Yaghoubian, Robert, Kane, Immaculata, Gallo, Gloria, Buck, Francis S, Buxbaum, Joel N

“…Isolated cardiac amyloidosis appearing late in life (senile cardiac amyloidosis) was first described in the 19th and early 20th centuries. 1 , 2 Pathological…”
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Somatotopic mapping of the human primary motor cortex with functional magnetic resonance imaging by RAO, S. M, BINDER, J. R, HAMMEKE, T. A, BANDETTINI, P. A, BOBHOLZ, J. A, FROST, J. A, MYKLEBUST, B. M, JACOBSON, R. D, HYDE, J. S

“…We applied functional magnetic resonance imaging (FMRI) to map the somatotopic organization of the primary motor cortex using voluntary movements of the hand,…”
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A familial syndrome of unilateral polymicrogyria affecting the right hemisphere by Chang, B S, Apse, K A, Caraballo, R, Cross, J H, Mclellan, A, Jacobson, R D, Valente, K D, Barkovich, A J, Walsh, C A

“…A number of familial syndromes of bilateral polymicrogyria (PMG) have been described, but reported unilateral PMG cases have generally been sporadic. The…”
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Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis by Mills, N E, Fishman, C L, Scholes, J, Anderson, S E, Rom, W N, Jacobson, D R

“…Lung cancer is the leading cause of cancer deaths in the United States. A long-standing goal of cancer researchers has been to develop tests that would…”
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Oral phenylalanine loading in dopa-responsive dystonia : A possible diagnostic test by HYLAND, K, FRYBURG, J. S, WILSON, W. G, BEBIN, E. M, ARNOLD, L. A, GUNASEKERA, R. S, JACOBSON, R. D, ROST-RUFFNER, E, TRUGMAN, J. M

“…To determine if there is abnormal phenylalanine and biopterin metabolism in patients with dopa-responsive dystonia (DRD), we measured plasma levels of…”
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Pax-6 Is First Expressed in a Region of Ectoderm Anterior to the Early Neural Plate: Implications for Stepwise Determination of the Lens by Li, Hua-Shun, Yang, Jun-Ming, Jacobson, Richard D., Pasko, Dean, Sundin, Olof

“…The Pax-6 gene encodes a DNA-binding transcription factor essential to normal development of the mammalian eye. We have found that in the chick embryo, the…”
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Cognitive Mapping Without Sight: four preliminary studies of spatial learning by Jacobson, R.Dan

“…This paper illustrates the application of cognitive mapping to people with visual impairments and blindness. It gives perspectives on past research, outlines…”
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Dystonia with motor delay in compound heterozygotes for GTP-cyclohydrolase I gene mutations by Furukawa, Y, Kish, S J, Bebin, E M, Jacobson, R D, Fryburg, J S, Wilson, W G, Shimadzu, M, Hyland, K, Trugman, J M

“…Mutations in the GTP-cyclohydrolase I (GCH) gene have been identified as a cause of two disorders: autosomal dominant hereditary progressive…”
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A protein associated with axon growth, GAP-43, is widely distributed and developmentally regulated in rat CNS by Jacobson, RD, Virag, I, Skene, JH

“…Development or regeneration of axons in several systems is accompanied by 20-100-fold increases in the synthesis of an acidic, axonally transported membrane…”
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Increased prevalence of K-ras oncogene mutations in lung adenocarcinoma by MILLS, N. E, FISHMAN, C. L, ROM, W. N, DUBIN, N, JACOBSON, D. R

“…Reported estimates of ras mutation prevalence in lung adenocarcinoma of 15-24% may be underestimates because of the insensitivity of the assays used. We have…”
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Techniques to Collect and Analyze the Cognitive Map Knowledge of Persons with Visual Impairment Or Blindness: Issues of Validity by Kitchin, R.M., Jacobson, R.D.

“…This article is an assessment of a variety of techniques used by researchers in the fields of geography, psychology, urban planning, and cognitive science to…”
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Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy by KLEIN, C. J, NAKUMURA, M, JACOBSON, D. R, LACY, M. Q, BENSON, M. D, PETERSEN, R. C

“…A 32-year-old man of Irish descent presented with severe progressive headache and sensorineural hearing loss. MRI/magnetic resonance angiography head scans…”
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Revised transthyretin ile 122 allele frequency in African-Americans by JACOBSON, D. R, PASTORE, R, POOL, S, MALENDOWICZ, S, KANE, I, SHIVJI, A, EMBURY, S. H, BALLAS, S. K, BUXBAUM, J. N

“…The transthyretin (TTR) Ile 122 variant is associated with cardiac amyloidosis in individuals of African descent. To determine the prevalence of the allele…”
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A highly sensitive assay for mutant ras genes and its application to the study of presentation and relapse genotypes in acute leukemia by Jacobson, D R, Mills, N E

“…Most studies of ras oncogene activation use assays for ras mutations based on the polymerase chain reaction (PCR) of DNA segments containing ras exons 1 and 2,…”
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Amyloid fibril composition and transthyretin gene structure in senile systemic amyloidosis by Gustavsson, A, Jahr, H, Tobiassen, R, Jacobson, D R, Sletten, K, Westermark, P

“…In many different forms of amyloidosis, transthyretin (TTR) comprises the major amyloid fibril protein. In the familial forms, various TTR mutations are linked…”
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Transthyretin Pro55, a variant associated with early-onset, aggressive, diffuse amyloidosis with cardiac and neurologic involvement by JACOBSON, D. R, MCFARLIN, D. E, KANE, I, BUXBAUM, J. N

“…Mutations in the protein transthyretin cause amyloidosis involving the heart, peripheral nerves, and other organs. A family from West Virginia developed an…”
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Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth by Basi, G S, Jacobson, R D, Virág, I, Schilling, J, Skene, J H

“…Nerve regeneration and developmental outgrowth of axons are both correlated with increased synthesis of an axonal membrane protein designated GAP-43…”
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Molecular genetic tumor markers in the early diagnosis and screening of non-small-cell lung cancer by Jacobson, D R, Fishman, C L, Mills, N E

“…Little progress has been made in decreasing lung cancer mortality by applying conventional methods to early diagnosis and screening. Recent advances in…”
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A Protein Induced during Nerve Growth (GAP-43) Is a Major Component of Growth-Cone Membranes by J. H. Pate Skene, Jacobson, Richard D., Snipes, G. Jackson, McGuire, C. Brain, Norden, Jeanette J., Freeman, John A.

“…Growth cones are specialized structures that form the distal tips of growing axons. During both normal development of the nervous system and regeneration of…”
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Variable-mode helical CT: imaging protocols by Tomiak, MM, Foley, WD, Jacobson, DR

“…Helical CT provides a rapidly acquired, accurately registered, two-dimensional data set during the phase of maximum vascular and parenchymal enhancement. The…”
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