Search Results - "Jacobson, A K"

Identification of A3 adenosine receptor agonists as novel non‐narcotic analgesics by Janes, K, Symons‐Liguori, AM, Jacobson, K A, Salvemini, D

“…Chronic pain negatively impacts the quality of life in a variety of patient populations. The current therapeutic repertoire is inadequate in managing patient…”
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International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors by Fredholm, B B, IJzerman, A P, Jacobson, K A, Klotz, K N, Linden, J

“…Four adenosine receptors have been cloned and characterized from several mammalian species. The receptors are named adenosine A 1 , A 2A , A 2B , and A 3 . The…”
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Antithrombotic therapy in atrial fibrillation by Laupacis, A, Albers, G, Dalen, J, Dunn, M I, Jacobson, A K, Singer, D E

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Comparison of Soil Sampling Devices for Soil Bulk Density Determination for Carbon Sequestration Monitoring by Cihacek, L. J., Foss, L. A., Jacobson, K. A.

“…Soil bulk density is often used to adjust soil carbon (C) values for changes in soil density because of management differences in C-sequestration studies…”
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Reply to: 'The discovery of a new class of synaptic transmitters in smooth muscle fifty years ago and amelioration of coronary artery thrombosis' by Abbracchio, M. P., Boeynaems, J.-M., Cattaneo, M., Virgilio, F. Di, Illes, P., Inoue, K., Jacobson, K. A., Teresa Miras-Portugal, M., Ralevic, V., Robson, S. C., Verkhratsky, A., Zimmermann, H.

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A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation by Trincavelli, M L, Tuscano, D, Marroni, M, Falleni, A, Gremigni, V, Ceruti, S, Abbracchio, M P, Jacobson, K A, Cattabeni, F, Martini, C

“…A(3) adenosine receptor activation has been previously demonstrated to result in both neuroprotective and neurodegenerative effects, depending upon specific…”
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Methanocarba Analogues of Purine Nucleosides as Potent and Selective Adenosine Receptor Agonists by Jacobson, Kenneth A, Ji, Xiao-duo, Li, An-Hu, Melman, Neli, Siddiqui, Maqbool A, Shin, Kye-Jung, Marquez, Victor E, Ravi, R. Gnana

“…Adenosine receptor agonists have cardioprotective, cerebroprotective, and antiinflammatory properties. We report that a carbocyclic modification of the ribose…”
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Adenosine-induced cell death: evidence for receptor-mediated signalling by Jacobson, K A, Hoffmann, C, Cattabeni, F, Abbracchio, M P

“…Adenosine modulates the proliferation, survival and apoptosis of many different cell types, ranging from epithelial, endothelial and smooth muscle cells, to…”
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CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver by Cohen, S., Stemmer, S.M., Zozulya, G., Ochaion, A., Patoka, R., Barer, F., Bar-Yehuda, S., Rath-Wolfson, L., Jacobson, K.A., Fishman, P.

“…The Gi protein‐associated A3 adenosine receptor (A3AR) is a member of the adenosine receptor family. Selective agonists at the A3AR, such as CF101 and CF102…”
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Towards a revised nomenclature for P1 and P2 receptors by Fredholm, Bertil B., Abbracchio, Maria P., Burnstock, Geoffrey, Dubyak, George R., Harden, T.Kendall, Jacobson, Kenneth A., Schwabe, Ulrich, Williams, Michael

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Comparison of Seven SO4-S Extraction Methods for Analysis by Turbidimetry or ICP Spectrometry by Cihacek, L. J., Yellajosula, G., Jacobson, K. A., Swenson, L.

“…Soil sulfur (S) analyses for fertilizer recommendations in the northern Great Plains often do not reflect crop S requirements. Seven SO ₄-S extraction methods…”
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Apoptosis by 2-chloro-2'-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells by BARBIERI, D, ABBRACCHIO, M. P, SALVIOLI, S, MONTI, D, COSSARIZZA, A, CERUTI, S, BRAMBILLA, R, CATTABENI, F, JACOBSON, K. A, FRANCESCHI, C

“…Adenosine has profound effects on immune cells and has been implicated in the intrathymic apoptotic deletion of T-cells during development. In order to…”
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Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis by OLAH, M. E, HONGZU REN, OSTROWSKI, J, JACOBSON, K. A, STILES, G. L

“…The bovine brain A1 adenosine receptor (A1AR) is distinct from other A1ARs in that it displays the unique agonist potency series of…”
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Interactions of Flavonoids and Other Phytochemicals with Adenosine Receptors by Ji, Xiao-duo, Melman, Neli, Jacobson, Kenneth A

“…Flavone derivatives and other phytochemicals were found to bind to three subtypes of adenosine receptors in the micromolar range. Affinity was determined in…”
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The As adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats by OCHAION, A, BAR-YEHUDA, S, PEREZ-LIZ, G, FISHMAN, P, COHEN, S, AMITAL, H, JACOBSON, K. A, JOSHI, B. V, GAO, Z. G, BARER, F, PATOKA, R, DEL VALLE, L

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Adenosine receptors as therapeutic targets by Jacobson, Kenneth A, Gao, Zhan-Guo

“…Adenosine receptors are major targets of caffeine, the most commonly consumed drug in the world. There is growing evidence that they could also be promising…”
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Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential by Jacobson, Kenneth A, Van Galen, Philip J. M, Williams, Michael

“…In the 10 years since Daly reviewed the potential of adenosine receptors as drug targets, considerable advances have been made in the area of purinergic…”
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A binding site model and structure-activity relationships for the rat A3 adenosine receptor by van Galen, P J, van Bergen, A H, Gallo-Rodriguez, C, Melman, N, Olah, M E, IJzerman, A P, Stiles, G L, Jacobson, K A

“…A novel adenosine receptor, the A3 receptor, has recently been cloned. We have systematically investigated the hitherto largely unexplored structure-activity…”
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Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells by Guerra, L, Favia, M, Fanelli, T, Calamita, G, Svetlo, M, Bagorda, A, Jacobson, K A, Reshkin, S J, Casavola, V

“…Nucleotide binding to purinergic P2Y receptors contributes to the regulation of a variety of physiological functions in renal epithelial cells. Here, we…”
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Fluorosulfonyl- and Bis-(β-chloroethyl)amino-phenylamino Functionalized Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine Derivatives:  Irreversible Antagonists at the Human A3 Adenosine Receptor and Molecular Modeling Studies by Baraldi, Pier Giovanni, Cacciari, Barbara, Moro, Stefano, Romagnoli, Romeo, Ji, Xiao-duo, Jacobson, Kenneth A, Gessi, Stefania, Borea, Pier Andrea, Spalluto, Giampiero

“…A series of pyrazolotriazolopyrimidines was previously reported to be highly potent and selective human A3 adenosine receptor antagonists (Baraldi et al. J…”
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