Search Results - "Jacobsen, J. P."

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice by Sidor, M M, Spencer, S M, Dzirasa, K, Parekh, P K, Tye, K M, Warden, M R, Arey, R N, Enwright, J F, Jacobsen, J P R, Kumar, S, Remillard, E M, Caron, M G, Deisseroth, K, McClung, C A

“…Disruptions in circadian rhythms and dopaminergic activity are involved in the pathophysiology of bipolar disorder, though their interaction remains unclear…”
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Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice by Jacobsen, J P R, Siesser, W B, Sachs, B D, Peterson, S, Cools, M J, Setola, V, Folgering, J H A, Flik, G, Caron, M G

“…Probably the foremost hypothesis of depression is the 5-hydroxytryptamine (5-HT, serotonin) deficiency hypothesis. Accordingly, anomalies in putative 5-HT…”
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Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice by Sidor, M M, Spencer, S M, Dzirasa, K, Parekh, P K, Tye, K M, Warden, M R, Arey, R N, Enwright, J F, Jacobsen, J P R, Kumar, S, Remillard, E M, Caron, M G, Deisseroth, K, McClung, C A

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Pulmonary arteriovenous malformations: screening procedures and pulmonary angiography in patients with hereditary hemorrhagic telangiectasia by Kjeldsen, A D, Oxhøj, H, Andersen, P E, Elle, B, Jacobsen, J P, Vase, P

“…Hereditary hemorrhagic telangiectasia (HHT) is a dominantly inherited disease with a high prevalence of pulmonary arteriovenous malformations (PAVMs). The…”
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Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice by Jacobsen, J.P.R, Redrobe, J.P, Hansen, H.H, Petersen, S, Bond, C.T, Adelman, J.P, Mikkelsen, J.D, Mirza, N.R

“…Abstract Small-conductance calcium-activated K+ channels 1–3 (SK1-3) are important for neuronal firing regulation and are considered putative CNS drug targets…”
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Binding Studies between Tetrathiafulvalene Derivatives and Cyclobis(paraquat-p-phenylene) by Nielsen, Mogens Brøndsted, Jeppesen, Jan Oskar, Lau, Jesper, Lomholt, Christian, Damgaard, Dorthe, Jacobsen, Jens Peter, Becher, Jan, Stoddart, J. Fraser

“…The complexation between a number of different π-electron donating TTF derivatives and the π-electron accepting tetracationic cyclophane…”
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SK3 K+ channel‐deficient mice have enhanced dopamine and serotonin release and altered emotional behaviors by Jacobsen, J. P. R., Weikop, P., Hansen, H. H., Mikkelsen, J. D., Redrobe, J. P., Holst, D., Bond, C. T., Adelman, J. P., Christophersen, P., Mirza, N. R.

“…SK3 K+ channels influence neuronal excitability and are present in 5‐hydroxytryptamine (5‐HT) and dopamine (DA) nuclei in the brain stem. We therefore…”
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The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine by Sachs, B D, Jacobsen, J P R, Thomas, T L, Siesser, W B, Roberts, W L, Caron, M G

“…The importance of reversing brain serotonin (5-HT) deficiency and promoting hippocampal neurogenesis in the mechanisms of action for antidepressants remain…”
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α-l-LNA (α-i-r ibo Configured Locked Nucleic Acid) Recognition of RNA. A Study by NMR Spectroscopy and Molecular Dynamics Simulations by Petersen, Michael, Håkansson, Anders E, Wengel, Jesper, Jacobsen, Jens Peter

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Erratum: Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice by Sidor, M M, Spencer, S M, Dzirasa, K, Parekh, P K, Tye, K M, Warden, M R, Arey, R N, Enwright, J F, Jacobsen, J P R, Kumar, S, Remillard, E M, Caron, M G, Deisseroth, K, McClung, C A

“…Correction to: Molecular Psychiatry (2015); advance online publication 6 January 2015; doi:10.1038/mp.2014.167 As the result of an editing error, the image in…”
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Concerted Intercalation and Minor Groove Recognition of DNA by a Homodimeric Thiazole Orange Dye by Bunkenborg, Jakob, Gadjev, Nikolai I, Deligeorgiev, Todor, Jacobsen, Jens Peter

“…The thiazole orange dye TOTO binds to double-stranded DNA (dsDNA) by a sequence selective bis-intercalation. Each chromophore is sandwiched between two base…”
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Locked Nucleic Acid (LNA) Recognition of RNA:  NMR Solution Structures of LNA:RNA Hybrids by Petersen, Michael, Bondensgaard, Kent, Wengel, Jesper, Jacobsen, Jens Peter

“…Locked nucleic acids (LNAs) containing one or more 2‘-O,4‘-C-methylene-linked bicyclic ribonucleoside monomers possess a number of the prerequisites of an…”
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Bis-Intercalation of a Homodimeric Thiazole Orange Dye in DNA in Symmetrical Pyrimidine-Pyrimidine-Purine-Purine Oligonucleotides by Hansen, Lene F., Jensen, Lisbeth K., Jacobsen, Jens Peter

“…One-and two-dimensional 1H NMR spectroscopy were used to characterize the binding of a homodimeric thiazole orange dye,…”
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Marriage and Migration: Comparing Gains and Losses from Migration for Couples and Singles by Jacobsen, Joyce P., Levin, Laurence M.

“…Objective. We calculate and compare the monetary returns to interstate mobility during the mid to late 1980s by sex and marital status, both overall and for…”
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Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice by TRINH, J. V, NEHRENBERG, D. L, JACOBSEN, J. P. R, CARON, M. G, WETSEL, W. C

“…Dopamine (DA) is a neurotransmitter that has been implicated in a wide variety of psychiatric disorders that include attention deficit-hyperactivity disorder…”
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Structural and Dynamic Characterization of the Heterodimeric and Homodimeric Complexes of Distamycin and 1-Methylimidazole-2-carboxamide-netropsin Bound to the Minor Groove of DNA by Geierstanger, Bernhard H, Jacobsen, Jens Peter, Mrksich, Milan, Dervan, Peter B, Wemmer, David E

“…NMR spectroscopy combined with molecular modeling was used to characterize a heterodimeric complex with Dst and 2-ImN bound in the minor groove of…”
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Monoaminergic dysregulation in glutathione-deficient mice: Possible relevance to schizophrenia? by Jacobsen, J.P.R., Rodriguiz, R.M., Mørk, A., Wetsel, W.C.

“…Several lines of research have implicated glutathione (GSH) in schizophrenia. For instance, GSH deficiency has been reported in the prefrontal cortex of…”
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NMR Studies of Fully Modified Locked Nucleic Acid (LNA) Hybrids:  Solution Structure of an LNA:RNA Hybrid and Characterization of an LNA:DNA Hybrid by Nielsen, Katrine E, Rasmussen, Jill, Kumar, Ravindra, Wengel, Jesper, Jacobsen, Jens Peter, Petersen, Michael

“…LNA is a bicyclic nucleic acid analogue that contains one or more 2‘-O,4‘-C methylene linkage(s), which effectively locks the furanose ring in a C3‘-endo…”
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Structural Studies of LNA:RNA Duplexes by NMR: Conformations and Implications for RNase H Activity by Bondensgaard, Kent, Petersen, Michael, Singh, Sanjay K., Rajwanshi, Vivek K., Kumar, Ravindra, Wengel, Jesper, Jacobsen, Jens Peter

“…We have used NMR and CD spectroscopy to study the conformations of modified oligonucleotides (locked nucleic acid, LNA) containing a conformationally…”
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Calculation of returns to job tenure revisited by Jacobsen, J. P., Levin, L. M.

“…This study considers the robustness of the effects on wages of job tenure and work experience among white adult men in the United States. The Survey of Income…”
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